Abdominal Aortic Aneurysm
January 2017 Issue

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Abdominal Aortic Aneurysm abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Abdominal Aortic Aneurysm. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Abdominal Aortic Aneurysm. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Abdominal Aortic Aneurysm every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.

1:Endovascular vs. Open Repair for Ruptured Abdominal Aortic Aneurysm.
Authors:Patelis N, Moris D, Karaolanis G, Georgopoulos S
Institution:Vascular Unit, First Department of Surgery, Laiko General Hospital, Medical School, National & Kapodistrian University of Athens, Athens, Greece.; Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.
Journal:Med Sci Monit Basic Res. 2016 Apr 19;22:34-44. doi: 10.12659/MSMBR.897601.

2:The association between body mass index and abdominal aortic aneurysm growth: a systematic review.
Authors:Takagi H, Umemoto T
Institution:1 Department of Cardiovascular Surgery, Shizuoka Medical Center, Shizuoka, Japan.
Journal:Vasa. 2016;45(2):119-24. doi: 10.1024/0301-1526/a000505.

3:Type II endoleaks: challenges and solutions.
Authors:Brown A, Saggu GK, Bown MJ, Sayers RD, Sidloff DA
Institution:Department of Vascular Surgery, Queens Medical Centre, University of Nottingham, Nottingham, UK.; Department of Vascular Surgery, Queens Medical Centre, University of Nottingham, Nottingham, UK; Department of Cardiovascular Sciences, National Institute for Health Research Leicester Cardiovascular Biomedical Research Unit, University of Leicester, Leicester, UK.
Journal:Vasc Health Risk Manag. 2016 Mar 2;12:53-63. doi: 10.2147/VHRM.S81275. eCollection 2016.

4:Endovascular repair of ruptured abdominal aortic aneurysms does not reduce later mortality compared with open repair.
Authors:Robinson WP, Schanzer A, Aiello FA, Flahive J, Simons JP, Doucet DR, Arous E, Messina LM
Institution:Division of Vascular and Endovascular Surgery, University of Massachusetts Medical School, Worcester, Mass. Electronic address: wprobins3@gmail.com.; Center for Outcomes Research, Department of Surgery, University of Massachusetts Medical School, Worcester, Mass.
Journal:J Vasc Surg. 2016 Mar;63(3):617-24. doi: 10.1016/j.jvs.2015.09.057.

5:Screening for abdominal aortic aneurysms.
Authors:Kostun ZW, Malik RK
Institution:Department of Vascular Surgery, Washington Hospital Center, 110 Irving St NW, Washington, DC 20010. Washington, DC 20010. Electronic address: rajesh.k.malikmd@medstar.net.
Journal:Clin Imaging. 2016 Mar-Apr;40(2):321-4. doi: 10.1016/j.clinimag.2015.12.009. Epub 2015 Dec 30.

6:Rupture of Abdominal Aortic Aneurysms in Patients Under Screening Age and Elective Repair Threshold.
Authors:Laine MT, Vanttinen T, Kantonen I, Halmesmaki K, Weselius EM, Laukontaus S, Salenius J, Aho PS, Venermo M
Institution:Department of Vascular Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. Electronic address: matti.laine@hus.fi.; Division of Vascular Surgery, Department of Surgery, Tampere University Hospital and University of Tampere, Tampere, Finland.
Journal:Eur J Vasc Endovasc Surg. 2016 Apr;51(4):511-6. doi: 10.1016/j.ejvs.2015.12.011. Epub 2016 Feb 4.

7:Predictors of 1-Year Survival After Endovascular Aneurysm Repair.
Authors:Fitridge RA, Boult M, de Loryn T, Cowled P, Barnes M
Institution:Discipline of Surgery, The University of Adelaide, Royal Adelaide Hospital and The Queen Elizabeth Hospital, Woodville, South Australia 5011, Australia. Electronic address: robert.fitridge@adelaide.edu.au.; CSIRO, Adelaide, South Australia 5000, Australia.
Journal:Eur J Vasc Endovasc Surg. 2016 Apr;51(4):528-34. doi: 10.1016/j.ejvs.2015.12.019. Epub 2016 Jan 28.

8:The ovation abdominal stent graft for the treatment of abdominal aortic aneurysms: current evidence and future perspectives.
Authors:Georgakarakos E, Ioannou CV, Georgiadis GS, Storck M, Trellopoulos G, Koutsias S, Lazarides MK
Institution:a Department of Vascular Surgery , 'Democritus' University of Thrace, University Hospital of Alexandroupolis , Alexandroupolis , Greece. Crete , Greece. Hospital of Alexandroupolis , Alexandroupolis , Greece. Karlsruhe , Germany. , Greece. Thessaly Medical School , Larissa , Greece. Hospital of Alexandroupolis , Alexandroupolis , Greece.
Journal:Expert Rev Med Devices. 2016;13(3):253-62. doi: 10.1586/17434440.2016.1147949. Epub 2016 Feb 16.

9:Indications for and outcome of open AAA repair in the endovascular era.
Authors:Wieker CM, Spazier M, Bockler D
Institution:Department of Vascular and Endovascular Surgery, Ruprecht-Karls University, Heidelberg, Germany - dittmar.boeckler@med.uni-heidelberg.de.
Journal:J Cardiovasc Surg (Torino). 2016 Apr;57(2):185-90. Epub 2016 Jan 28.

10:Risk factors and consequences of persistent type II endoleaks.
Authors:Lo RC, Buck DB, Herrmann J, Hamdan AD, Wyers M, Patel VI, Fillinger M, Schermerhorn ML
Institution:Division of Vascular and Endovascular Surgery, Beth Israel Deaconess Medical Center, Boston, Mass. Center, Boston, Mass. Center, Boston, Mass. Center, Boston, Mass. Center, Boston, Mass. Boston, Mass. Center, Boston, Mass. Electronic address: mscherme@bidmc.harvard.edu.
Journal:J Vasc Surg. 2016 Apr;63(4):895-901. doi: 10.1016/j.jvs.2015.10.088. Epub 2016 Jan 12.

11:New developments in the treatment of ruptured AAA.
Authors:Tsilimparis N, Saleptsis V, Rohlffs F, Wipper S, Debus ES, Kolbel T
Institution:German Aortic Center, University Heart Center, University Hospital Hamburg-Eppendorf, Hamburg Germany - n.tsilimparis@uke.de.
Journal:J Cardiovasc Surg (Torino). 2016 Apr;57(2):233-41. Epub 2016 Jan 19.

12:Abdominal aortic aneurysm.
Authors:Setacci F, Galzerano G, De Donato G, Benevento D, Guerrieri MW, Ruzzi U, Borrelli MP, Setacci C
Institution:"P. Valdoni" Department of Surgery, Sapienza University of Rome, Policlinico Umberto I, Rome, Italy - carlo.setacci@unisi.it.
Journal:J Cardiovasc Surg (Torino). 2016 Feb;57(1):72-85.

13:Abdominal aortic aneurysms in women.
Authors:Lo RC, Schermerhorn ML
Institution:Beth Israel Deaconess Medical Center, Boston, Mass. mscherme@bidmc.harvard.edu.
Journal:J Vasc Surg. 2016 Mar;63(3):839-44. doi: 10.1016/j.jvs.2015.10.087. Epub 2015 Dec 30.

14:Risk assessment and risk scores in the management of aortic aneurysms.
Authors:Von Meijenfeldt GC, Van Der Laan MJ, Zeebregts CJ, Balm R, Verhagen HJ
Institution:Division of Vascular Surgery, Department of Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands - h.verhagen@erasmusmc.nl.
Journal:J Cardiovasc Surg (Torino). 2016 Apr;57(2):162-71. Epub 2015 Dec 23.

15:Thirty-Day Outcomes after Elective Percutaneous or Open Endovascular Repair of Abdominal Aortic Aneurysms.
Authors:Kauvar DS, Martin ED, Givens MD
Institution:Department of Surgery, Dwight D. Eisenhower Army Medical Center, Fort Gordon, GA; Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD. Electronic address: davekauvar@gmail.com. GA.
Journal:Ann Vasc Surg. 2016 Feb;31:46-51. doi: 10.1016/j.avsg.2015.10.009. Epub 2015 Nov 30.

16:Prognostic and predictive biomarkers of abdominal aortic aneurysm growth rate.
Authors:Deeg MA, Meijer CA, Chan LS, Shen L, Lindeman JH
Institution:a a Lilly Research Laboratories, Eli Lilly & Co. , Indianapolis , IN , USA. The Netherlands. The Netherlands.
Journal:Curr Med Res Opin. 2016;32(3):509-17. doi: 10.1185/03007995.2015.1128406. Epub 2016 Jan 14.

17:Systematic Review and Meta-analysis of Factors Influencing Survival Following Abdominal Aortic Aneurysm Repair.
Authors:Khashram M, Williman JA, Hider PN, Jones GT, Roake JA
Institution:Department of Surgery, University of Otago, Christchurch, New Zealand; Department of Vascular Endovascular & Transplant Surgery Christchurch Hospital, New Zealand. Electronic address: manar.khashram@gmail.com. New Zealand. of Vascular Endovascular & Transplant Surgery Christchurch Hospital, New Zealand.
Journal:Eur J Vasc Endovasc Surg. 2016 Feb;51(2):203-15. doi: 10.1016/j.ejvs.2015.09.007. Epub 2015 Oct 23.

18:Life expectancy and causes of death after repair of intact and ruptured abdominal aortic aneurysms.
Authors:Bastos Goncalves F, Ultee KH, Hoeks SE, Stolker RJ, Verhagen HJ
Institution:Department of Vascular Surgery, Erasmus University Medical Centre, Rotterdam, The Netherlands; Department of Vascular Surgery, Hospital de Santa Marta, CHLC, NOVA Medical School, Lisbon, Portugal. Electronic address: f.bastosgoncalves@erasmusmc.nl. Netherlands. Netherlands. Netherlands. Netherlands.
Journal:J Vasc Surg. 2016 Mar;63(3):610-6. doi: 10.1016/j.jvs.2015.09.030. Epub 2015 Nov 6.

19:Endovascular grafts for abdominal aortic aneurysm.
Authors:Steuer J, Lachat M, Veith FJ, Wanhainen A
Institution:Clinic for Cardiovascular Surgery, University Hospital, Zurich, Switzerland Department of Surgery, Stockholm South Hospital, SE-118 83 Stockholm, Sweden joste@live.se. Division of Vascular Surgery, Department of Surgery, New York University, New York, NY, USA Division of Vascular Surgery, The Cleveland Clinic, Cleveland, OH, USA. Sweden.
Journal:Eur Heart J. 2016 Jan 7;37(2):145-51. doi: 10.1093/eurheartj/ehv593. Epub 2015 Nov 4.

20:Abdominal Aortic Aneurysms and Risk Factors for Adverse Events.
Authors:Ahmed R, Ghoorah K, Kunadian V
Institution:From the *Faculty of Medical Sciences, Newcastle University Medical School, Newcastle, UK; daggerCardiothoracic Centre, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundations Trust, Newcastle, UK; and double daggerFaculty of Medical Sciences, Institute of Cellular Medicine, Newcastle University, Newcastle, UK.
Journal:Cardiol Rev. 2016 Mar-Apr;24(2):88-93. doi: 10.1097/CRD.0000000000000052.

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What Our Customers Are Saying...

"Ten years ago I was diagnosed as having an abdominal aortic aneurysm while undergoing a routine ultrasound. While I was told of the possible fatal consequences of a rupture, I received no guidance from any of my physicians. The MediFocus Guidebook on Abdominal Aortic Aneurysm is the only source that provided me with the information that gave me confidence that I can find expert help should I need elective surgery. I could never have located all of the detailed, valuable information contained in the Guidebook. Having access to it has given me a level of confidence that I have the latest and most important information concerning this condition."
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