| | Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.
Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Atrial Fibrillation abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Atrial Fibrillation. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Atrial Fibrillation. You can access the summaries of each article referenced below by simply clicking on the article Title.
We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Atrial Fibrillation every 3 months. Thank you for your ongoing subscription to this publication.
Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.
| Authors: | Zhang H, Xue Z, Yi D, Li X, Tan Y, Li J |
| Institution: | Department of Cardiovascular Medicine, Xiangdong Hospital Hunan normal University. | | Journal: | Int Heart J. 2020 Mar 28;61(2):231-238. doi: 10.1536/ihj.19-202. Epub 2020 Mar 14. |
| Authors: | Bo M, Giannecchini F, Papurello M, Brunetti E |
| Institution: | Section of Geriatrics, Departement of Medical Sciences, University of Turin, Citta della Salute e della Scienza, Molinette Hospital, Turin. mario.bo@unito.it. | | Journal: | Monaldi Arch Chest Dis. 2020 Mar 9;90(1). doi: 10.4081/monaldi.2020.1252. |
| Authors: | Hsieh HL, Hsu SC, Cheng HS, Chen CY, Huang WC, Sue YM, Lin FY, Shih CM, Chen JW, Lin SJ, Huang PH, Liu CT |
| Institution: | Division of Nephrology, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan. | | Journal: | PLoS One. 2020 Jan 30;15(1):e0228405. doi: 10.1371/journal.pone.0228405. eCollection 2020. |
| Authors: | Tseng CH, Chung WJ, Li CY, Tsai TH, Lee CH, Hsueh SK, Wu CC, Cheng CI |
| Institution: | Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital Kaohsiung Branch, Kaohsiung. | | Journal: | Medicine (Baltimore). 2020 Jan;99(2):e18517. doi: 10.1097/MD.0000000000018517. |
| Authors: | Garcia DA, Fisher DA, Mulder H, Wruck L, De Caterina R, Halvorsen S, Granger CB, Held C, Wallentin L, Alexander JH, Lopes RD |
| Institution: | Division of Hematology, University of Washington School of Medicine, Seattle, WA. Duke Clinical Research Institute, Durham, NC; Division of Cardiology, Department of Medicine, Duke University School of Medicine, Durham, NC. Electronic address: renato.lopes@duke.edu. | | Journal: | Am Heart J. 2020 Mar;221:1-8. doi: 10.1016/j.ahj.2019.10.013. Epub 2019 Oct 31. |
| Authors: | Voskoboinik A, Kalman JM, De Silva A, Nicholls T, Costello B, Nanayakkara S, Prabhu S, Stub D, Azzopardi S, Vizi D, Wong G, Nalliah C, Sugumar H, Wong M, Kotschet E, Kaye D, Taylor AJ, Kistler PM |
| Institution: | From the Heart Center, Alfred Hospital (A.V., T.N., B.C., S.N., S.P., D.S., S.A., D.V., H.S., D.K., A.J.T., P.M.K.), the Baker Heart and Diabetes Institute (A.V., B.C., S.P., D.S., H.S., A.J.T., P.M.K. | | Journal: | N Engl J Med. 2020 Jan 2;382(1):20-28. doi: 10.1056/NEJMoa1817591. |
| Authors: | Reiffel JA, Verma A, Kowey PR, Halperin JL, Gersh BJ, Elkind MSV, Ziegler PD, Kaplon RE, Sherfesee L, Wachter R |
| Institution: | Department of Medicine, Division of Cardiology, Vagelos College of Physicians and Surgeons, Columbia University, 630 West 168th Street, New York, NY. Electronic address: jar2@columbia.edu. Clinic and Policlinic for Cardiology, University Hospital Leipzig, Liebigstrae 20, Leipzig, Germany. Electronic address: Rolf.Wachter@medizin.uni-leipzig.de. | | Journal: | Am Heart J. 2020 Jan;219:128-136. doi: 10.1016/j.ahj.2019.07.016. |
| Authors: | Godino C, Melillo F, Bellini B, Mazzucca M, Pivato CA, Rubino F, Figini F, Mazzone P, Della Bella P, Margonato A, Colombo A, Montorfano M |
| Institution: | Cardiology Unit, San Raffaele Hospital, Milan, Italy. | | Journal: | EuroIntervention. 2020 Apr 17;15(17):1548-1554. doi: 10.4244/EIJ-D-19-00507. |
| Authors: | Ravi V, Pulipati P, Vij A, Kodumuri V |
| Institution: | Division of Cardiology, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois. Division of Cardiology, Department of Internal Medicine, Ascension All Saints Hospital, Racine, Wisconsin. Electronic address: vamsiko@yahoo.com. | | Journal: | Am J Cardiol. 2020 Jan 1;125(1):19-28. doi: 10.1016/j.amjcard.2019.09.045. Epub 2019 Oct 11. |
| Authors: | Pokorney SD, Holmes DN, Shrader P, Thomas L, Fonarow GC, Mahaffey KW, Gersh BJ, Kowey PR, Naccarelli GV, Freeman JV, Singer DE, Washam JB, Peterson ED, Piccini JP, Reiffel JA |
| Institution: | Duke University Medical Center, Durham, NC; Duke Clinical Research Institute, Durham, NC. Electronic address: sean.pokorney@duke.edu. Columbia University Medical Center, New York, NY. | | Journal: | Am Heart J. 2020 Feb;220:145-154. doi: 10.1016/j.ahj.2019.09.017. Epub 2019 Oct 23. |
| Authors: | Sutter JS, Lokhnygina Y, Daubert JP, Bahnson T, Jackson K, Koontz JI, Sun AY, Hegland DD, Thomas KL, Jackson L, Lewis R, Granger C, Piccini JP, Atwater BD |
| Institution: | Duke University Medical Center, Durham, NC. Electronic address: jsw44@duke.edu. Duke University Medical Center, Durham, NC; Duke Center for Atrial Fibrillation, Durham, NC. | | Journal: | Am Heart J. 2020 Feb;220:89-96. doi: 10.1016/j.ahj.2019.11.010. Epub 2019 Nov 22. |
| Authors: | Lee KJ, Kim BJ, Han MK, Kim JT, Choi KH, Shin DI, Yeo MJ, Cha JK, Kim DH, Nah HW, Kim DE, Ryu WS, Park JM, Kang K, Lee SJ, Kim JG, Oh MS, Yu KH, Lee BC, Hong KS, Cho YJ, Choi JC, Park TH, Park SS, Kwon JH, Kim WJ, Lee J, Lee JS, Lee J, Gorelick PB, Bae HJ |
| Institution: | From the Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (K.-J.L., B.J.K., M.-K.H., H.-J.B.). | | Journal: | Stroke. 2020 Jan;51(1):162-169. doi: 10.1161/STROKEAHA.119.026847. Epub 2019 Dec 4. |
| Authors: | Makani A, Saba S, Jain SK, Bhonsale A, Sharbaugh MS, Thoma F, Wang Y, Marroquin OC, Lee JS, Estes NAM, Mulukutla SR |
| Institution: | Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania. Electronic address: mulukutlasr@upmc.edu. | | Journal: | Am J Cardiol. 2020 Jan 15;125(2):210-214. doi: 10.1016/j.amjcard.2019.10.033. Epub 2019 Nov 1. |
| Authors: | Wingerter R, Steiger N, Burrows A, Estes NAM 3rd |
| Institution: | College of Medicine at University of Central Florida, Orlando, Florida. University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania. | | Journal: | Am J Cardiol. 2020 Jan 15;125(2):289-297. doi: 10.1016/j.amjcard.2019.10.018. Epub 2019 Oct 26. |
| Authors: | Obeidat M, Burgess M, Lip GYH |
| Institution: | Department of Cardiology, Aintree Hospital, Liverpool, UK. Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart and Chest Hospital, Liverpool, UK; Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg Un | | Journal: | Heart Fail Clin. 2020 Jan;16(1):107-120. doi: 10.1016/j.hfc.2019.08.007. |
| Authors: | Loring Z, Shrader P, Allen LA, Blanco R, Chan PS, Ezekowitz MD, Fonarow GC, Freeman JV, Gersh BJ, Mahaffey KW, Naccarelli GV, Pieper K, Reiffel JA, Singer DE, Steinberg BA, Thomas LE, Peterson ED, Piccini JP |
| Institution: | Division of Cardiology, Duke University Medical Center, Durham, NC; Duke Clinical Research Institute, Durham, NC. Electronic address: zak.loring@duke.edu. | | Journal: | Am Heart J. 2020 Jan;219:21-30. doi: 10.1016/j.ahj.2019.10.008. Epub 2019 Nov 8. |
| Authors: | Diederichsen SZ, Haugan KJ, Brandes A, Graff C, Krieger D, Kronborg C, Holst AG, Nielsen JB, Køber L, Højberg S, Svendsen JH |
| Institution: | Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, Copenhagen, Denmark. Electronic address: Soeren.Zoega.Diederichsen@regionh.dk. Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, Copenhagen, Denmark; Laboratory for Molecular Cardiology, Department of Cardiology, Rigshospitalet, Copenhagen U | | Journal: | Am Heart J. 2020 Jan;219:117-127. doi: 10.1016/j.ahj.2019.09.009. Epub 2019 Oct 20. |
| Authors: | Karamchandani K, Khanna AK, Bose S, Fernando RJ, Walkey AJ |
| Institution: | From the Department of Anesthesiology & Perioperative Medicine, Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania. Evans Center for Implementation and Improvement Sciences, Department of Medicine and the Pulmonary Center, Boston University School of Medicine, Boston, Massachusetts. | | Journal: | Anesth Analg. 2020 Jan;130(1):2-13. doi: 10.1213/ANE.0000000000004474. |
| Authors: | Lapenna E, De Bonis M, Giambuzzi I, Del Forno B, Ruggeri S, Cireddu M, Gulletta S, Castiglioni A, Alfieri O, Della Bella P, Benussi S |
| Institution: | Department of Cardiac Surgery, IRCCS San Raffaele Hospital, Vita-Salute San Raffaele University, Milan, Italy. Electronic address: lapenna.elisabetta@hsr.it. Department of Cardiac Surgery, Spedali Civili di Brescia, University Hospital, Brescia, Italy. | | Journal: | Ann Thorac Surg. 2020 Jan;109(1):124-131. doi: 10.1016/j.athoracsur.2019.05.061. Epub 2019 Jul 17. |
| Authors: | Saito Y, Kobayashi Y |
| Institution: | Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8677, Japan. saitoyuichi1984@gmail.com. | | Journal: | Cardiovasc Interv Ther. 2020 Jan;35(1):44-51. doi: 10.1007/s12928-019-00600-1. Epub 2019 Jul 8. |
| Authors: | Anguita Sánchez M, Bertomeu Martínez V, Ruiz Ortiz M, Cequier Fillat Á, Roldán Rabadán I, Muñiz García J, Badimón Maestro L, Esteve Pastor MA, Marín Ortuño F |
| Institution: | Servicio de Cardiologia, Hospital Universitario Reina Sofia, Cordoba, Spain. Electronic address: manuelanguita@secardiologi-a.es. Servicio de Cardiologia, Hospital Universitario Virgen de la Arrixaca, IMIB-Arrixaca, CIBERCV, EL Palmar, Murcia, Spain. | | Journal: | Rev Esp Cardiol (Engl Ed). 2020 Jan;73(1):14-20. doi: 10.1016/j.rec.2019.02.021. Epub 2019 May 31. |
| Authors: | Cruz-González I, Ince H, Kische S, Schmitz T, Schmidt B, Gori T, Foley D, de Potter T, Tschishow W, Vireca E, Stein K, Boersma LV |
| Institution: | Servicio de Cardiologia, Hospital Universitario de Salamanca, Instituto de Investigacion Biomedica de Salamanca (IBSAL), Centro de Investigacion Biomedica en Red Enfermedades Cardiovasculares (CIBER-CV Cardiologie, St Antonius Hospital, Nieuwegein, The Netherlands. | | Journal: | Rev Esp Cardiol (Engl Ed). 2020 Jan;73(1):21-27. doi: 10.1016/j.rec.2019.02.008. Epub 2019 Apr 5. |
| Authors: | Ojo A, Yandrapalli S, Veseli G, Karim M, Aronow WS, Sharma M, Frishman WH, Naidu SS, Jacobson JT, Iwai S |
| Institution: | From the Division of Cardiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA. Division of Cardiology, New York Medical College/Westchester Medical Center, Valhalla, NY. | | Journal: | Cardiol Rev. 2020 Jan/Feb;28(1):42-51. doi: 10.1097/CRD.0000000000000240. |
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What Our Customers Are Saying... "The MediFocus Guidebook on Atrial Fibrillation has enhanced and clearly explained this condition for me. It has also enabled me to make choices with confidence regarding my treatment. The references in the medical literature section has put me in touch with the research base in this country. Many thanks."
E.B.
Seaford, East Sussex
"I found the MediFocus Guidebook on Atrial Fibrillation extremely informative and very easy to understand. As a result of the information in the Guidebook, I'm able to discuss my problem with my doctor in a more informed manner and make better decisions regarding treatment."
J.T.F.
Agoura Hills, California
"The Medifocus Guidebook on Atrial Fibrillation gave me far more information than was available from my doctor and helped me understand my condition."
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Rancho Santa Fe, California
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