Atrial Fibrillation
October 2017 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Atrial Fibrillation abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Atrial Fibrillation. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Atrial Fibrillation. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Atrial Fibrillation every 3 months. Thank you for your ongoing subscription to this publication.

Sincerely,
Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Availability of patient decision aids for stroke prevention in atrial fibrillation: A systematic review.
Authors:O'Neill ES, Grande SW, Sherman A, Elwyn G, Coylewright M
Institution:Section of Cardiovascular Medicine, Heart and Vascular Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH.; Section of Cardiovascular Medicine, Heart and Vascular Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH; The Preference Laboratory, The Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, NH. Electronic address: megan.coylewright@dartmouth.edu.
Journal:Am Heart J. 2017 Sep;191:1-11. doi: 10.1016/j.ahj.2017.05.014. Epub 2017 Jun 3.

2:Effect of Dietary Intake of Saturated Fatty Acids on the Development of Atrial Fibrillation and the Effect of Replacement of Saturated With Monounsaturated and Polyunsaturated Fatty Acids.
Authors:Dinesen PT, Joensen AM, Rix TA, Tjonneland A, Schmidt EB, Lundbye-Christensen S, Overvad K
Institution:Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark; Aalborg AF Study Group, Aalborg University Hospital, Aalborg, Denmark. Electronic address: p.dinesen@rn.dk. Copenhagen, Denmark. of Clinical Medicine, Aalborg University, Aalborg, Denmark. Clinical Biostatistics, Aalborg University, Aalborg, Denmark. AF Study Group, Aalborg University Hospital, Aalborg, Denmark; Department of Public Health, Section for Epidemiology, Aarhus University, Aarhus, Denmark.
Journal:Am J Cardiol. 2017 Oct 1;120(7):1129-1132. doi: 10.1016/j.amjcard.2017.06.053. Epub 2017 Jul 14.

3:Modifiable Risk Factors and Atrial Fibrillation.
Authors:Lau DH, Nattel S, Kalman JM, Sanders P
Institution:From: Centre for Heart Rhythm Disorders, South Australian Health and Medical Research Institute, University of Adelaide and Royal Adelaide Hospital, (D.H.L., P.S.); Department of Medicine, Universite de Montreal, Research Center, Montreal Heart Institute, Quebec, Canada (S.N.); Institute of Pharmacology, West German Heart and Vascular Center, Faculty of Medicine, University Duisburg-Essen, Germany (S.N.); and Department of Cardiology, Royal Melbourne Hospital and the Department of Medicine, University of Melbourne, Victoria, Australia (J.M.K.). prash.sanders@adelaide.edu.au.
Journal:Circulation. 2017 Aug 8;136(6):583-596. doi: 10.1161/CIRCULATIONAHA.116.023163.

4:Changes in Oral Anticoagulant Prescribing for Stroke Prevention in Patients With Atrial Fibrillation.
Authors:Admassie E, Chalmers L, Bereznicki LR
Institution:Division of Pharmacy, School of Medicine, University of Tasmania, Tasmania, Australia. Electronic address: Endalkachew.alamneh@utas.edu.au. Australia.
Journal:Am J Cardiol. 2017 Oct 1;120(7):1133-1138. doi: 10.1016/j.amjcard.2017.06.055. Epub 2017 Jul 14.

5:Guideline-Adherent Antithrombotic Treatment Improves Outcomes in Patients With Atrial Fibrillation: Insights From the Community-Based Darlington Atrial Fibrillation Registry.
Authors:Mazurek M, Shantsila E, Lane DA, Wolff A, Proietti M, Lip GYH
Institution:Institute for Cardiovascular Sciences, University of Birmingham, Birmingham, UK; Department of Cardiology, Congenital Heart Diseases and Electrotherapy, Silesian Centre for Heart Diseases, Zabrze, Poland. Columbia, Canada. Electronic address: g.y.h.lip@bham.ac.uk.
Journal:Mayo Clin Proc. 2017 Aug;92(8):1203-1213. doi: 10.1016/j.mayocp.2017.05.023.

6:Should We Perform Catheter Ablation for Asymptomatic Atrial Fibrillation?
Authors:Kalman JM, Sanders P, Rosso R, Calkins H
Institution:From Department of Cardiology, Royal Melbourne Hospital, Parkville, Australia (J.M.K.); Faculty of Medicine, Dentistry, and Health Sciences, University of Melbourne, Australia (J.M.K.); Centre for Heart Rhythm Disorders, South Australian Health and Medical Research Institute, University of Adelaide and Royal Adelaide Hospital, Australia (P.S.); Department of Cardiology, Tel Aviv Sourasky Medical Center, Sackler School of Medicine, Tel Aviv University, Israel (R.S.); and Department of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, MD (H.C.). jon.kalman@mh.org.au.
Journal:Circulation. 2017 Aug 1;136(5):490-499. doi: 10.1161/CIRCULATIONAHA.116.024926.

7:Contemporary Atrial Fibrillation Management: A Comparison of the Current AHA/ACC/HRS, CCS, and ESC Guidelines.
Authors:Andrade JG, Macle L, Nattel S, Verma A, Cairns J
Institution:University of British Columbia, Vancouver, British Columbia, Canada; Montreal Heart Institute, Universite de Montreal, Montreal, Quebec, Canada. Electronic address: Jason.guy.andrade@umontreal.ca.
Journal:Can J Cardiol. 2017 Aug;33(8):965-976. doi: 10.1016/j.cjca.2017.06.002. Epub 2017 Jun 9.

8:Compliance in weight control reduces atrial fibrillation worsening: A retrospective cohort study.
Authors:Fioravanti F, Brisinda D, Sorbo AR, Lombardi G, La Brocca L, Fenici R
Institution:Biomagnetism and Clinical Physiology International Center (BACPIC), Catholic University of the Sacred Heart, Rome, Italy. Electronic address: feniciri@rm.unicatt.it.
Journal:Nutr Metab Cardiovasc Dis. 2017 Aug;27(8):711-716. doi: 10.1016/j.numecd.2017.04.007. Epub 2017 Apr 27.

9:Non-vitamin K antagonist oral anticoagulants: impact of non-adherence and discontinuation.
Authors:Rivera-Caravaca JM, Esteve-Pastor MA, Roldan V, Marin F, Lip GYH
Institution:a Institute of Cardiovascular Sciences , University of Birmingham , Birmingham , UK. Morales Meseguer, Instituto Murciano de Investigacion Biosanitaria (IMIB-Arrixaca) , Murcia , Spain. UK. Arrixaca, Instituto Murciano de Investigacion Biosanitaria (IMIB-Arrixaca), CIBER-CV , Murcia , Spain. Morales Meseguer, Instituto Murciano de Investigacion Biosanitaria (IMIB-Arrixaca) , Murcia , Spain. Arrixaca, Instituto Murciano de Investigacion Biosanitaria (IMIB-Arrixaca), CIBER-CV , Murcia , Spain. UK. University , Aalborg , Denmark.
Journal:Expert Opin Drug Saf. 2017 Sep;16(9):1051-1062. doi: 10.1080/14740338.2017.1351542. Epub 2017 Jul 12.

10:Surgical Ablation of Atrial Fibrillation in the United States: Trends and Propensity Matched Outcomes.
Authors:Badhwar V, Rankin JS, Ad N, Grau-Sepulveda M, Damiano RJ, Gillinov AM, McCarthy PM, Thourani VH, Suri RM, Jacobs JP, Cox JL
Institution:Department of Cardiovascular and Thoracic Surgery, West Virginia University, Morgantown, West Virginia. Electronic address: vinay.badhwar@wvumedicine.org. Morgantown, West Virginia. Morgantown, West Virginia. Ohio. Chicago, Illinois. Ohio. Baltimore, Maryland. Chicago, Illinois.
Journal:Ann Thorac Surg. 2017 Aug;104(2):493-500. doi: 10.1016/j.athoracsur.2017.05.016. Epub 2017 Jun 29.

11:Modifiable Risk Factors in Atrial Fibrillation: The Role of Alcohol, Obesity, and Sleep Apnea.
Authors:Sidhu K, Tang A
Institution:Department of Cardiology, Western University, London, Ontario, Canada. Electronic address: kdsidhu26@gmail.com.
Journal:Can J Cardiol. 2017 Jul;33(7):947-949. doi: 10.1016/j.cjca.2017.04.006. Epub 2017 Apr 21.

12:Risk of ischemic stroke after atrial fibrillation diagnosis: A national sample cohort.
Authors:Son MK, Lim NK, Kim HW, Park HY
Institution:Division of Cardiovascular and Rare Diseases, Center for Biomedical Science, Korea National Institute of Health, Chungcheongbuk-do, Republic of Korea.
Journal:PLoS One. 2017 Jun 21;12(6):e0179687. doi: 10.1371/journal.pone.0179687. eCollection 2017.

13:Efficacy and safety of traditional Chinese medicine on thromboembolic events in patients with atrial fibrillation: A systematic review and meta-analysis.
Authors:Wang Z, Tang Z, Zhu W, Ge L, Ge J
Institution:Department of Cardiology, The Fifth People's Hospital of Shanghai, Fudan University, 801, Heqing Rd, Minhang District, Shanghai 200240, China. Electronic address: linerzhiqiu@126.com. China. Electronic address: 13211020018@fudan.edu.cn. Zhongshan Hospital, Fudan University, 180, fenglin Road, Xuhui District, Shanghai 200032, China. Electronic address: zhu.wenqing@zs-hospital.sh.cn. Zhongshan Hospital, Fudan University, 180, fenglin Road, Xuhui District, Shanghai 200032, China. Electronic address: ge.lei@zs-hospital.sh.cn. Zhongshan Hospital, Fudan University, 180, fenglin Road, Xuhui District, Shanghai 200032, China. Electronic address: ge.junbo@zs-hospital.sh.cn.
Journal:Complement Ther Med. 2017 Jun;32:1-10. doi: 10.1016/j.ctim.2017.03.006. Epub 2017 Mar 19.

14:Antithrombotic Therapy and First Myocardial Infarction in Patients With Atrial Fibrillation.
Authors:Lee CJ, Pallisgaard JL, Olesen JB, Carlson N, Lamberts M, Gislason GH, Torp-Pedersen C, Brandes A, Husted SE, Johnsen SP, Hansen ML
Institution:Department of Health Science and Technology, Aalborg University, and Department of Clinical Epidemiology and Cardiology, Aalborg University Hospital, Aalborg, Denmark; Department of Cardiology, Copenhagen University Hospital Gentofte, Hellerup, Denmark. Electronic address: cjilee@outlook.com. Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. Denmark. Denmark; Danish Heart Foundation, Copenhagen, Denmark; Department of Internal Medicine, Holbaek Hospital, Holbaek, Denmark. Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Danish Heart Foundation, Copenhagen, Denmark. of Clinical Epidemiology and Cardiology, Aalborg University Hospital, Aalborg, Denmark. Denmark; Heart Centre, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark; Department of Cardiology, Zealand University Hospital, Roskilde, Denmark.
Journal:J Am Coll Cardiol. 2017 Jun 20;69(24):2901-2909. doi: 10.1016/j.jacc.2017.04.033.

15:Statin Adherence Is Associated With Reduced Recurrent Stroke Risk in Patients With or Without Atrial Fibrillation.
Authors:Flint AC, Conell C, Ren X, Kamel H, Chan SL, Rao VA, Johnston SC
Institution:From the Division of Research, Kaiser Permanente Northern California, Oakland, (A.C.F., C.C.); Department of Neuroscience (A.C.F., S.L.C., V.A.R.) and Department of Cardiology (X.R.), Kaiser Permanente, Redwood City, CA; Department of Neurology, Cornell University, New York, NY (H.K.); and Department of Neurology, University of Texas at Austin (S.C.J.). alexander.c.flint@kp.org.
Journal:Stroke. 2017 Jul;48(7):1788-1794. doi: 10.1161/STROKEAHA.117.017343. Epub 2017 Jun 8.

16:Chocolate intake and risk of clinically apparent atrial fibrillation: the Danish Diet, Cancer, and Health Study.
Authors:Mostofsky E, Berg Johansen M, Tjonneland A, Chahal HS, Mittleman MA, Overvad K
Institution:Cardiovascular Epidemiology Research Unit, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA. Massachusetts, USA. Dentistry, Western University, London, Ontario, Canada. Boston, Massachusetts, USA. Massachusetts, USA. Denmark.
Journal:Heart. 2017 Aug;103(15):1163-1167. doi: 10.1136/heartjnl-2016-310357. Epub 2017 May 23.

17:Lean Body Mass Is the Predominant Anthropometric Risk Factor for Atrial Fibrillation.
Authors:Fenger-Gron M, Overvad K, Tjonneland A, Frost L
Institution:Research Unit for General Practice and Section for General Medical Practice, Department of Public Health, Aarhus University, Aarhus, Denmark. Electronic address: mfgr@ph.au.dk. Denmark; Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark.
Journal:J Am Coll Cardiol. 2017 May 23;69(20):2488-2497. doi: 10.1016/j.jacc.2017.03.558.

18:Renal Function Considerations for Stroke Prevention in Atrial Fibrillation.
Authors:Fanikos J, Burnett AE, Mahan CE, Dobesh PP
Institution:Department of Pharmacy, Brigham and Women's Hospital, Boston, Mass. Electronic address: jfanikos@partners.org. Albuquerque. Presbyterian Healthcare Services, Albuquerque.
Journal:Am J Med. 2017 Sep;130(9):1015-1023. doi: 10.1016/j.amjmed.2017.04.015. Epub 2017 May 11.

19:Thromboembolic and bleeding risks in patients undergoing atrial fibrillation ablation: oral anticoagulation perspectives.
Authors:Briceno DF, Madan N, Romero J, Londono A, Villablanca PA, Natale A, Di Biase L
Institution:a Division of Cardiovascular Disease , Montefiore Medical Center, Albert Einstein College of Medicine , Bronx , NY , USA.; b Texas Cardiac Arrhythmia Institute, Heart & Vascular Department , St. David's Medical Center , Austin , TX , USA.
Journal:Expert Opin Drug Saf. 2017 Jul;16(7):769-777. doi: 10.1080/14740338.2017.1325867. Epub 2017 Jun 15.

20:Left Atrial Appendage Closure Device in Atrial Fibrillation.
Authors:Giudici MC, Bhave PD
Institution:Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA. Electronic address: michael-c-giudici@uiowa.edu.
Journal:Cardiol Clin. 2017 May;35(2):297-300. doi: 10.1016/j.ccl.2016.12.011.

21:Management of Major Bleeding in Patients With Atrial Fibrillation Treated With Non-Vitamin K Antagonist Oral Anticoagulants Compared With Warfarin in Clinical Practice (from Phase II of the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation [ORBIT-AF II]).
Authors:Steinberg BA, Simon DN, Thomas L, Ansell J, Fonarow GC, Gersh BJ, Kowey PR, Mahaffey KW, Peterson ED, Piccini JP
Institution:Division of Cardiovascular Medicine, University of Utah Health Sciences Center, Salt Lake City, Utah; Department of Medicine, Duke University Medical Center, Durham, North Carolina; Duke Clinical Research Institute, Durham, North Carolina. Electronic address: benjamin.steinberg@hsc.utah.edu. California. California. Duke Clinical Research Institute, Durham, North Carolina. Duke Clinical Research Institute, Durham, North Carolina.
Journal:Am J Cardiol. 2017 May 15;119(10):1590-1595. doi: 10.1016/j.amjcard.2017.02.015. Epub 2017 Mar 28.

22:Intracranial hemorrhage in patients with atrial fibrillation receiving anticoagulation therapy.
Authors:Lopes RD, Guimaraes PO, Kolls BJ, Wojdyla DM, Bushnell CD, Hanna M, Easton JD, Thomas L, Wallentin L, Al-Khatib SM, Held C, Gabriel Melo de Barros E Silva P, Alexander JH, Granger CB, Diener HC
Institution:Duke Clinical Research Institute, Duke Health, Durham, NC. Germany.
Journal:Blood. 2017 Jun 1;129(22):2980-2987. doi: 10.1182/blood-2016-08-731638. Epub 2017 Mar 29.

23:Viewpoint: Stroke Prevention in Recent Guidelines for the Management of Patients with Atrial Fibrillation: An Appraisal.
Authors:Potpara TS, Lip GYH, Blomstrom-Lundqvist C, Chiang CE, Camm AJ
Institution:School of Medicine, Belgrade University, Serbia; Cardiology Clinic, Clinical Center of Serbia, Belgrade. Sciences, University of Birmingham, United Kingdom; Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Denmark. Electronic address: g.y.h.lip@bham.ac.uk. Sweden. General Hospital and National Yang-Ming University, Taiwan. Kingdom.
Journal:Am J Med. 2017 Jul;130(7):773-779. doi: 10.1016/j.amjmed.2017.02.026. Epub 2017 Mar 24.

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