Chronic Pancreatitis
March 2022 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Chronic Pancreatitis abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Chronic Pancreatitis. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Chronic Pancreatitis. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Chronic Pancreatitis every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:The features and clinical outcomes of inflammatory bowel disease associated with autoimmune pancreatitis: A greater awareness is needed.
Authors:Conti Bellocchi MC, Marconato E, Lamonaca L, Cattani Mottes M, Ciccocioppo R, Carrara S, de Pretis N, Gabbrielli A, Crinò SF, Frulloni L
Institution:Department of Medicine, Gastroenterology and Digestive Endoscopy Unit, Pancreas Institute, University of Verona, Verona, Italy.
Journal:Medicine (Baltimore). 2022 Jan 28;101(4):e28602. doi: 10.1097/MD.0000000000028602.

2:Acute and Chronic Pancreatitis Disease Prevalence, Classification, and Comorbidities: A Cohort Study of the UK BioBank.
Authors:Spagnolo DM, Greer PJ, Ohlsen CS, Mance S, Ellison M, Breze C, Busby B, Whitcomb DC, Haupt M
Institution:Ariel Precision Medicine, Inc., Pittsburgh, Pennsylvania, USA.
Journal:Clin Transl Gastroenterol. 2022 Jan 19;13(1):e00455. doi: 10.14309/ctg.0000000000000455.

3:Predictors of Glycemic Outcomes at 1 Year Following Pediatric Total Pancreatectomy With Islet Autotransplantation.
Authors:Swauger SE, Hornung LN, Elder DA, Balamurugan AN, Vitale DS, Lin TK, Nathan JD, Abu-El-Haija M
Institution:Division of Endocrinology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH. Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH.
Journal:Diabetes Care. 2022 Feb 1;45(2):295-302. doi: 10.2337/dc21-1222.

4:Idiopathic chronic pancreatitis: Beyond antioxidants.
Authors:Mehta RM, Pandol SJ, Joshi PR
Institution:Department of Gastroenterology, Surat Institute of Digestive Science (SIDS) Hospital and Research Centre, Surat 395002, Gujarat, India. clinicalgastroenterology@gmail.com. Department of Gastroenterology and Clinical Research, SIDS Hospital and Research Centre, Surat 395002, Gujarat, India.
Journal:World J Gastroenterol. 2021 Nov 21;27(43):7423-7432. doi: 10.3748/wjg.v27.i43.7423.

5:Genetic Evaluation of Pancreatitis.
Authors:Fu Y, Lucas AL
Institution:Henry D. Janowitz Division of Gastroenterology, One Gustave L. Levy Place, Box 1069, New York, NY 10029, USA; Samuel Bronfman Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, USA. Electronic address: aimee.lucas@mssm.edu.
Journal:Gastrointest Endosc Clin N Am. 2022 Jan;32(1):27-43. doi: 10.1016/j.giec.2021.08.006.

6:Impact of genetic testing and smoking on the distribution of risk factors in patients with recurrent acute and chronic pancreatitis.
Authors:Gurakar M, Jalaly NY, Faghih M, Boortalary T, Azadi JR, Khashab MA, Fan C, Kalloo AN, Zaheer A, Singh VK, Afghani E
Institution:Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD, USA. Pancreatitis Center, Johns Hopkins Medical Institutions, Baltimore, MD, USA.
Journal:Scand J Gastroenterol. 2022 Jan;57(1):91-98. doi: 10.1080/00365521.2021.1984573. Epub 2021 Oct 18.

7:Surgery for chronic pancreatitis: the comparison of two high-volume centers reveals lack of a uniform operative management.
Authors:Surci N, Bassi C, Salvia R, Marchegiani G, Casetti L, Deiro G, Bergmann C, Tamandl D, Schindl M, Mühlbacher J, Sahora K
Institution:Department of Surgery, Vienna General Hospital, Medical University of Vienna, Vienna, Austria. Hospital, University and Hospital Trust of Verona, Verona, Italy. Hospital, University and Hospital Trust of Verona, Verona, Italy. Hospital, University and Hospital Trust of Verona, Verona, Italy. Hospital, University and Hospital Trust of Verona, Verona, Italy. Hospital, University and Hospital Trust of Verona, Verona, Italy. Hospital, University and Hospital Trust of Verona, Verona, Italy. Vienna, Austria. Vienna, Austria. Vienna, Austria.
Journal:Langenbecks Arch Surg. 2021 Dec;406(8):2669-2677. doi: 10.1007/s00423-021-02335-1. Epub 2021 Oct 1.

8:Immediate and Long-Term Outcomes of Percutaneous Radiological Interventions for Hemorrhagic Complications in Acute and Chronic Pancreatitis.
Authors:Madhusudhan KS, Gopi S, Singh AN, Agarwal L, Gunjan D, Srivastava DN, Garg PK
Institution:Department of Radiodiagnosis and Interventional Radiology, All India Institute of Medical Sciences, New Delhi, India. Electronic address: drmadhuks@gmail.com. India. Delhi, India. Delhi, India. India. Medical Sciences, New Delhi, India. India.
Journal:J Vasc Interv Radiol. 2021 Nov;32(11):1591-1600.e1. doi: 10.1016/j.jvir.2021.08.004. Epub 2021 Aug 17.

9:Efficacy and safety of rituximab in autoimmune pancreatitis type 1: our experiences and systematic review of the literature.
Authors:Nikolic S, Panic N, Hintikka ES, Dani L, Rutkowski W, Hedström A, Steiner C, Löhr JM, Vujasinovic M
Institution:Department of Medicine, Huddinge, Karolinska Institute, Stockholm, Sweden. Centre Maribor, Maribor, Slovenia. Sweden. Karolinska University Hospital, Stockholm, Sweden. Sweden. Institute, Stockholm, Sweden. Sweden. Sweden. Sweden. Institute, Stockholm, Sweden. Sweden.
Journal:Scand J Gastroenterol. 2021 Nov;56(11):1355-1362. doi: 10.1080/00365521.2021.1963837. Epub 2021 Aug 19.

10:Successful spinal cord stimulation for chronic pancreatitis and post-laminectomy pain.
Authors:Cox CJ, Wilkinson MM, Erdek MA
Institution:East Tennessee State University Quillen College of Medicine, 178 Maple Ave., Mountain Home, TN 37684, USA. Department of Anesthesiology & Critical Care Medicine, Johns Hopkins University School of Medicine, 550 N. Broadway, Suite 301, Baltimore, MD 21205, USA.
Journal:Pain Manag. 2022 Mar;12(2):123-129. doi: 10.2217/pmt-2021-0065. Epub 2021 Aug 12.

11:Current advances in the management of chronic pancreatitis.
Authors:Mann R, Boregowda U, Vyas N, Gajendran M, Umapathy CP, Sayana H, Echavarria J, Patel S, Saligram S
Institution:Department of Internal Medicine, Saint Agnes Medical Center, 1303 E Herndon Ave, Fresno, CA 93720, USA. Department of Gastroenterology and Advanced endoscopy, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA. Electronic address: drsaligram@yahoo.com.
Journal:Dis Mon. 2021 Dec;67(12):101225. doi: 10.1016/j.disamonth.2021.101225. Epub 2021 Jun 24.

12:The in situ near-total pancreatectomy (LIVOCADO procedure) for end-staged chronic pancreatitis.
Authors:Baron RD, Sheel ARG, Farooq A, Kleeff J, Contin P, Halloran CM, Neoptolemos JP
Institution:Department of Pancreato-Biliary Surgery, The Royal Liverpool University Hospital, Liverpool, UK. Liverpool, UK. University of Liverpool, Liverpool, UK. Germany. Heidelberg, Im Neuenheimer Feld 420, 69120, Heidelberg, Baden-Württemberg, Germany. Liverpool, UK. University of Liverpool, Liverpool, UK. Heidelberg, Im Neuenheimer Feld 420, 69120, Heidelberg, Baden-Württemberg, Germany. john.neoptolemos@med.uni-heidelberg.de.
Journal:Langenbecks Arch Surg. 2021 Dec;406(8):2657-2668. doi: 10.1007/s00423-021-02107-x. Epub 2021 Jun 25.

13:Prodromal Signs and Symptoms of Chronic Pancreatitis: A Systematic Review.
Authors:Thompson BS, Philcox S, Devereaux B, Metz AJ, Croagh D, Gray A, Hamarneh Z, Windsor JA, Neale RE
Institution:Department of Population Health, QIMR Berghofer Medical Research Institute. Department of Population Health, QIMR Berghofer Medical Research Institute, and School of Public Health, University of Queensland.
Journal:J Clin Gastroenterol. 2022 Jan 1;56(1):e1-e10. doi: 10.1097/MCG.0000000000001544.

14:Endoscopic management of chronic pancreatitis.
Authors:Nabi Z, Lakhtakia S
Institution:Asian Institute of Gastroenterology, Hyderabad, India.
Journal:Dig Endosc. 2021 Nov;33(7):1059-1072. doi: 10.1111/den.13968. Epub 2021 Apr 2.

15:Incidence and Risk of Pancreatic Cancer in Patients with a New Diagnosis of Chronic Pancreatitis.
Authors:Munigala S, Subramaniam DS, Subramaniam DP, Burroughs TE, Conwell DL, Sheth SG
Institution:Saint Louis University Center for Outcomes Research (SLUCOR), 3545 Lafayette Ave, Salus Center 4th Floor, SLUCOR Office, St. Louis, MO, 63104, USA. satish.munigala@slu.edu. Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Journal:Dig Dis Sci. 2022 Feb;67(2):708-715. doi: 10.1007/s10620-021-06886-7. Epub 2021 Feb 25.

16:Prevalence and Risk Factors for Osteopathy in Chronic Pancreatitis.
Authors:Tang XY, Ru N, Li Q, Qian YY, Sun H, Zhu JH, He L, Wang YC, Hu LH, Li ZS, Zou WB, Liao Z
Institution:Department of Gastroenterology, Changhai Hospital, The Second Military Medical University, Shanghai, China. The Second Military Medical University, Shanghai, China. University, Shanghai, China. China. The First People's Hospital of Taicang, Taicang, Jiangsu Province, China. University, Shanghai, China. University, Shanghai, China. University, Shanghai, China. University, Shanghai, China. China. University, Shanghai, China. University, Shanghai, China. University, Shanghai, China. China. University, Shanghai, China. China.
Journal:Dig Dis Sci. 2021 Nov;66(11):4008-4016. doi: 10.1007/s10620-020-06732-2. Epub 2021 Jan 12.

17:Efficacy of Pregabalin and Antioxidants Combination in Reducing Pain in Chronic Pancreatitis: A Double Blind Randomized Trial.
Authors:Sureshkumar S, Omang A, Anandhi A, Rajesh BS, Abdulbasith KM, Vijayakumar C, Palanivel C, Pazhanivel M, Kate V
Institution:Department of Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, 605006, India. drvikramkate@gmail.com.
Journal:Dig Dis Sci. 2021 Nov;66(11):4017-4025. doi: 10.1007/s10620-020-06711-7. Epub 2020 Nov 18.

18:Endoscopic ultrasound-guided fine needle aspiration versus biopsy for diagnosis of autoimmune pancreatitis: Systematic review and comparative meta-analysis.
Authors:Yoon SB, Moon SH, Song TJ, Kim JH, Kim MH
Institution:Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea. University College of Medicine, Anyang, South Korea. Korea. Medicine, Seoul, South Korea. University College of Medicine, Anyang, South Korea. Korea. Medicine, Seoul, South Korea.
Journal:Dig Endosc. 2021 Nov;33(7):1024-1033. doi: 10.1111/den.13866. Epub 2020 Nov 17.

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What Our Customers Are Saying...

"Thank you. Thank you. Thank you. I am a 37-year old man with chronic pancreatitis. I didn't know where to start looking for information about this condition on the Internet. Medifocus gave me a great start. The explanations of my illness were very comprehensive and now I can talk better with my doctor about my treatment options."
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Utrecht, Netherlands


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Rubinsonia, Pennsylvania


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