Chronic Pancreatitis
March 2019 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Chronic Pancreatitis abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Chronic Pancreatitis. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Chronic Pancreatitis. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Chronic Pancreatitis every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Autoantibody detection is not recommended for chronic pancreatitis: a cross-sectional Study of 557 patients.
Authors:Zeng XP, Liu TT, Hao L, Xin L, Wang T, He L, Pan J, Wang D, Bi YW, Ji JT, Liao Z, Du TT, Lin JH, Zhang D, Guo HL, Chen H, Zou WB, Li BR, Cong ZJ, Wang LS, Xu ZL, Xie T, Liu MH, Deng AM, Li ZS, Hu LH
Institution:Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China. zhaoshen-li@hotmail.com.; Department of Gastroenterology, Changhai Hospital, The Second Military Medical University, Shanghai, China. zhaoshen-li@hotmail.com.; Department of Laboratory Medicine, Changhai Hospital, The Second Military Medical University, Shanghai, China. amdeng70@163.com.; Department of Gastroenterology, Hainan Branch of Chinese PLA General Hospital, Sanya, China.; Digestive Endoscopy Center, Changhai Hospital, The Second Military Medical University, Shanghai, China. zhaoshen-li@hotmail.com.
Journal:BMC Gastroenterol. 2019 Feb 14;19(1):31. doi: 10.1186/s12876-019-0947-7.

2:Mechanism-based pain management in chronic pancreatitis - is it time for a paradigm shift?
Authors:Kuhlmann L, Olesen SS, Olesen AE, Arendt-Nielsen L, Drewes AM
Institution:a Centre for Pancreatic Diseases and Mech-Sense, Department of Gastroenterology and Hepatology , Aalborg University Hospital , Aalborg , Denmark. Denmark. and Hepatology , Aalborg University Hospital , Aalborg , Denmark. and Hepatology , Aalborg University Hospital , Aalborg , Denmark. Aalborg , Denmark. and Hepatology , Aalborg University Hospital , Aalborg , Denmark.
Journal:Expert Rev Clin Pharmacol. 2019 Mar;12(3):249-258. doi: 10.1080/17512433.2019.1571409. Epub 2019 Feb 5.

3:Risk factor for steatorrhea in pediatric chronic pancreatitis patients.
Authors:Hao L, Wang T, He L, Bi YW, Zhang D, Zeng XP, Xin L, Pan J, Wang D, Ji JT, Du TT, Lin JH, Wang LS, Zou WB, Chen H, Xie T, Guo HL, Li BR, Liao Z, Xu ZL, Li ZS, Hu LH
Institution:Department of Gastroenterology, Hainan Branch of Chinese PLA General Hospital, Hainan, China.; Department of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China. zhaoshen-li@hotmail.com.; Department of Gastroenterology, Changhai Hospital, The Second Military Medical University, Shanghai, China. zhaoshen-li@hotmail.com.; Department of Gastroenterology, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, Guangdong, China. 78249073@qq.com.; Department of Gastroenterology, Zhongda Hospital, Southeast University, Nanjing, China.
Journal:BMC Gastroenterol. 2018 Dec 5;18(1):182. doi: 10.1186/s12876-018-0902-z.

4:Risk factors and prediction score for chronic pancreatitis: A nationwide population-based cohort study.
Authors:Lin YC, Kor CT, Su WW, Hsu YC
Institution:Division of Gastroenterology, Department of Internal Medicine, Changhua Christian Hospital, Changhua 50006, Taiwan. 144315@cch.org.tw. Taiwan. Hospital, Changhua 50006, Taiwan. Hospital, Changhua 50006, Taiwan.
Journal:World J Gastroenterol. 2018 Nov 28;24(44):5034-5045. doi: 10.3748/wjg.v24.i44.5034.

5:The Management of Chronic Pancreatitis.
Authors:Patel V, Willingham F
Institution:Division of Digestive Diseases, Department of Medicine, Emory University School of Medicine, 1365 Clifton Road, Northeast, Building B, Suite 1200, Atlanta, GA 30322, USA. Hospital, Children's Healthcare of Atlanta, Emory University School of Medicine, 1365 Clifton Road, Northeast, Building B, Suite 1200, Atlanta, GA 30322, USA. Electronic address: field.willingham@emory.edu.
Journal:Med Clin North Am. 2019 Jan;103(1):153-162. doi: 10.1016/j.mcna.2018.08.012.

6:Combination of longitudinal pancreaticojejunostomy with coring-out of the pancreatic head (Frey procedure) and distal pancreatectomy for chronic pancreatitis.
Authors:Sato H, Ishida M, Motoi F, Sakata N, Aoki T, Suzuki H, Yamamura A, Karasawa H, Hata T, Ohtsuka H, Mizuma M, Morikawa T, Hayashi H, Nakagawa K, Kamei T, Naitoh T, Egawa S, Unno M
Institution:Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan. Japan. mishida@surg.med.tohoku.ac.jp. Japan. Fukuoka University, Fukuoka, Japan. Japan. Japan. Japan. Japan. Japan. Japan. Japan. Japan. Japan. Japan. Japan. Japan. Research Institute of Disaster Science, Tohoku University, Sendai, Japan. Japan.
Journal:Surg Today. 2019 Feb;49(2):137-142. doi: 10.1007/s00595-018-1720-1. Epub 2018 Sep 26.

7:Pancreatitis.
Authors:Hammad AY, Ditillo M, Castanon L
Institution:Department of Surgery, Allegheny General Hospital, 320 East North Avenue, Pittsburgh, PA 15212, USA. Pittsburgh, PA 15212, USA. Pittsburgh, PA 15212, USA. Electronic address: lourdes.castanon@ahn.org.
Journal:Surg Clin North Am. 2018 Oct;98(5):895-913. doi: 10.1016/j.suc.2018.06.001. Epub 2018 Jul 17.

8:Fecal fat and energy loss in pancreas exocrine insufficiency: the role of pancreas enzyme replacement therapy.
Authors:Erchinger F, Ovre AKN, Aarseth MM, Engjom T, Bronstad I, Dimcevski G, Gudbrandsen OA, Tjora E
Institution:a Department of Medicine , Voss Hospital, Haukeland University Hospital , Voss , Norway. Hospital , Bergen , Norway. Hospital , Bergen , Norway.
Journal:Scand J Gastroenterol. 2018 Sep;53(9):1132-1138. doi: 10.1080/00365521.2018.1499801. Epub 2018 Sep 7.

9:Guidelines for the Diagnostic Cross Sectional Imaging and Severity Scoring of Chronic Pancreatitis.
Authors:Frokjaer JB, Akisik F, Farooq A, Akpinar B, Dasyam A, Drewes AM, Haldorsen IS, Morana G, Neoptolemos JP, Olesen SS, Petrone MC, Sheel A, Shimosoegawa T, Whitcomb DC
Institution:Department of Radiology, Aalborg University Hospital, Denmark; Department of Clinical Medicine, Aalborg University, Denmark. Electronic address: jebf@rn.dk.; Department of Radiology, Indiana University, Indianapolis, USA.; Department of Radiology, Royal Liverpool University Hospital, Liverpool, United Kingdom.; Department of Radiology, Koc University School of Medicine, Istanbul, Turkey.; Department of Radiology, University of Pittsburgh and UPMC, Pittsburgh, PA, USA.
Journal:Pancreatology. 2018 Oct;18(7):764-773. doi: 10.1016/j.pan.2018.08.012. Epub 2018 Aug 28.

10:Endoscopic Islet Autotransplantation Into Gastric Submucosa-1000-Day Follow-up of Patients.
Authors:Wszola M, Berman A, Gorski L, Ostaszewska A, Serwanska-Swietek M, Krajewska M, Lipinska A, Chmura A, Kwiatkowski A
Institution:Foundation of Research and Science Development, Otwock, Poland. Electronic address: michal.wszola@medispace.pl. Warsaw, Poland. Warsaw, Poland. University, Warsaw, Poland. Warsaw, Poland. Warsaw, Poland. General and Transplantation Surgery, Warsaw Medical University, Warsaw, Poland.
Journal:Transplant Proc. 2018 Sep;50(7):2119-2123. doi: 10.1016/j.transproceed.2018.02.138. Epub 2018 Mar 14.

11:Pancreatitis-Associated Genes and Pancreatic Cancer Risk: A Systematic Review and Meta-analysis.
Authors:Cazacu IM, Farkas N, Garami A, Balasko M, Mosdosi B, Alizadeh H, Gyongyi Z, Rakonczay Z Jr, Vigh E, Habon T, Czopf L, Lazarescu MA, Eross B, Sahin-Toth M, Hegyi P
Institution:Institute of Bioanalysis. Pecs, Hungary. Pecs, Hungary. Medicine, Boston University, Boston, MA.
Journal:Pancreas. 2018 Oct;47(9):1078-1086. doi: 10.1097/MPA.0000000000001145.

12:The diagnostic value of Rosemont and Japanese diagnostic criteria for 'indeterminate', 'suggestive', 'possible' and 'early' chronic pancreatitis.
Authors:Sheel ARG, Baron RD, Sarantitis I, Ramesh J, Ghaneh P, Raraty MGT, Yip V, Sutton R, Goulden MR, Campbell F, Farooq A, Healey P, Jackson R, Halloran CM, Neoptolemos JP
Institution:Department of Clinical Cancer Medicine, Institute of Translational Medicine, The University of Liverpool, UK. Liverpool, UK. University of Liverpool, UK. Liverpool, UK. University of Liverpool, UK. Liverpool, UK. Liverpool, UK. University of Liverpool, UK. University Hospital, Liverpool, UK. UK. Liverpool, UK. University of Liverpool, UK. Electronic address: halloran@liv.ac.uk.
Journal:Pancreatology. 2018 Oct;18(7):774-784. doi: 10.1016/j.pan.2018.08.002. Epub 2018 Aug 7.

13:Chronic pancreatitis correlates with increased risk of herpes zoster in a population-based retrospective cohort study.
Authors:Lai SW, Lin CL, Liao KF
Institution:College of Medicine, China Medical University, Taichung, Taiwan. Taiwan. Taiwan. Chi General Hospital, No. 66, Sec. 1, Fongsing Road, Tanzi District, Taichung 427, Taiwan.
Journal:J Hepatobiliary Pancreat Sci. 2018 Sep;25(9):412-417. doi: 10.1002/jhbp.575. Epub 2018 Sep 6.

14:Exocrine Pancreatic Insufficiency and Malnutrition in Chronic Pancreatitis: Identification, Treatment, and Consequences.
Authors:Min M, Patel B, Han S, Bocelli L, Kheder J, Vaze A, Wassef W
Institution:Division of Gastroenterology, UC Denver School of Medicine, Denver, CO. Worcester, MA.
Journal:Pancreas. 2018 Sep;47(8):1015-1018. doi: 10.1097/MPA.0000000000001137.

15:Improving nutritional status assessment in patients with chronic pancreatitis.
Authors:Hintaran AD, Chenault MN, Verhaegh BPM, Reijven PLM, Masclee AAM, Keulemans YCA
Institution:Maastricht University Medical Centre, Department of Gastroenterology, Maastricht, The Netherlands. Electronic address: a.hintaran@student.maastrichtuniversity.nl. Netherlands. The Netherlands. Netherlands. The Netherlands.
Journal:Pancreatology. 2018 Oct;18(7):785-791. doi: 10.1016/j.pan.2017.08.010. Epub 2017 Aug 30.

16:Impact of Obesity on Pediatric Acute Recurrent and Chronic Pancreatitis.
Authors:Uc A, Zimmerman MB, Wilschanski M, Werlin SL, Troendle D, Shah U, Schwarzenberg SJ, Rhee S, Pohl JF, Perito ER, Palermo JJ, Ooi CY, Liu Q, Lin TK, Morinville VD, McFerron BA, Husain SZ, Himes R, Heyman MB, Gonska T, Giefer MJ, Gariepy CE, Freedman SD, Fishman DS, Bellin MD, Barth B, Abu-El-Haija M, Lowe ME
Institution:Department of Biostatistics, University of Iowa, Iowa City, IA. Dallas, TX. Medical School, Boston, MA. Minneapolis, MN. CA. CA. Cincinnati, OH. University of New South Wales and Sydney Children's Hospital, Randwick Sydney, Australia. Cincinnati, OH. Montreal, Quebec, Canada. of Medicine, Indianapolis, IN. CA. Minneapolis, MN. Dallas, TX. Cincinnati, OH.
Journal:Pancreas. 2018 Sep;47(8):967-973. doi: 10.1097/MPA.0000000000001120.

17:Incidence and Predictors of 30-Day Readmission Among Patients Hospitalized for Chronic Pancreatitis.
Authors:Garg SK, Sarvepalli S, Campbell JP, Anugwom C, Singh D, Wadhwa V, Singh R, Sanaka MR
Institution:Department of Hospital Medicine, Medicine Institute, Cleveland Clinic, Cleveland, OH. Institute, Cleveland Clinic, Cleveland, OH.
Journal:Pancreas. 2018 Sep;47(8):1008-1014. doi: 10.1097/MPA.0000000000001113.

18:Patient and Procedural Factors Associated With Increased Islet Cell Yield in Total Pancreatectomy With Islet Autotransplantation.
Authors:Trinh KV, Smith KD, Gardner TB
Institution:From the Sections of Gastroenterology and Hepatology and.
Journal:Pancreas. 2018 Sep;47(8):985-989. doi: 10.1097/MPA.0000000000001116.

19:Lateral Pancreaticojejunostomy for Chronic Pancreatitis and Pancreatic Ductal Dilation in Children.
Authors:Shah AA, Petrosyan M, Kane TD
Institution:1 Department of Surgery, Howard University Hospital and College of Medicine , Washington, District of Columbia.; 2 Department of Pediatric Surgery, Children's National Medical Center , George Washington University School of Medicine, Washington, District of Columbia.
Journal:J Laparoendosc Adv Surg Tech A. 2018 Nov;28(11):1397-1402. doi: 10.1089/lap.2018.0136. Epub 2018 Jun 6.

20:Expression and clinical significance of EGF and TGF-alpha in chronic pancreatitis and pancreatic cancer.
Authors:Hao C, Li Z, Zhang X, Zhang H, Shang H, Bao J, Wang H
Institution:Department of Hepatobiliary and Pancreatic Surgery, Tianjin Nankai Hospital, Tianjin, China.; Department of Hepatobiliary and Pancreatic Surgery, Tianjin Nankai Hospital, Tianjin, China - lizhonglian2016@163.com.
Journal:Minerva Endocrinol. 2018 Sep;43(3):253-258. doi: 10.23736/S0391-1977.17.02721-3. Epub 2017 Nov 10.

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