Chronic Pancreatitis
August 2017 Issue

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Chronic Pancreatitis abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Chronic Pancreatitis. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Chronic Pancreatitis. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Chronic Pancreatitis every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content, Inc.

1:Novel and Experimental Therapies in Chronic Pancreatitis.
Authors:Jagannath S, Garg PK
Institution:Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India. Delhi, India.
Journal:Dig Dis Sci. 2017 Jul;62(7):1751-1761. doi: 10.1007/s10620-017-4604-0. Epub 2017 May 27.

2:Genetic Risk in Chronic Pancreatitis: The Trypsin-Dependent Pathway.
Authors:Hegyi E, Sahin-Toth M
Institution:Center for Exocrine Disorders, Department of Molecular and Cell Biology, Boston University Henry M. Goldman School of Dental Medicine, 72 East Concord Street, Evans-433, Boston, MA, 02118, USA.
Journal:Dig Dis Sci. 2017 Jul;62(7):1692-1701. doi: 10.1007/s10620-017-4601-3. Epub 2017 May 23.

3:Medical Management of Pain in Chronic Pancreatitis.
Authors:Singh VK, Drewes AM
Institution:Pancreatitis Center, Division of Gastroenterology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Hepatology, Aalborg University Hospital, Molleparkvej, 9000, Aalborg, Denmark.
Journal:Dig Dis Sci. 2017 Jul;62(7):1721-1728. doi: 10.1007/s10620-017-4605-z. Epub 2017 May 18.

4:Chronic Pancreatitis: Current Status and Challenges for Prevention and Treatment.
Authors:Lew D, Afghani E, Pandol S
Institution:Cedars-Sinai Medical Center, 8700 Beverly Blvd., Los Angeles, CA, 90048, USA.
Journal:Dig Dis Sci. 2017 Jul;62(7):1702-1712. doi: 10.1007/s10620-017-4602-2. Epub 2017 May 13.

5:Complications of Chronic Pancreatitis.
Authors:Ramsey ML, Conwell DL, Hart PA
Institution:Section of Pancreatic Disorders, Division of Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, 410 West Tenth Avenue, Columbus, OH, 3210, USA.
Journal:Dig Dis Sci. 2017 Jul;62(7):1745-1750. doi: 10.1007/s10620-017-4518-x. Epub 2017 Mar 9.

6:Surgical Approaches to Chronic Pancreatitis: Indications and Techniques.
Authors:Dua MM, Visser BC
Institution:Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA.
Journal:Dig Dis Sci. 2017 Jul;62(7):1738-1744. doi: 10.1007/s10620-017-4526-x. Epub 2017 Mar 9.

7:Endoscopic Therapies for Chronic Pancreatitis.
Authors:Adler JM, Gardner TB
Institution:Section of Gastroenterology and Hepatology, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH, 03756, USA.
Journal:Dig Dis Sci. 2017 Jul;62(7):1729-1737. doi: 10.1007/s10620-017-4502-5. Epub 2017 Mar 3.

8:Surgical strategies in the treatment of chronic pancreatitis: An updated systematic review and meta-analysis of randomized controlled trials.
Authors:Zhao X, Cui N, Wang X, Cui Y
Institution:aDepartment of Surgery, Tianjin Nankai Hospital, Tianjin, China bNankai Clinical College, Tianjin Medical University, Tianjin, China.
Journal:Medicine (Baltimore). 2017 Mar;96(9):e6220. doi: 10.1097/MD.0000000000006220.

9:Quality of Life in Chronic Pancreatitis is Determined by Constant Pain, Disability/Unemployment, Current Smoking, and Associated Co-Morbidities.
Authors:Machicado JD, Amann ST, Anderson MA, Abberbock J, Sherman S, Conwell DL, Cote GA, Singh VK, Lewis MD, Alkaade S, Sandhu BS, Guda NM, Muniraj T, Tang G, Baillie J, Brand RE, Gardner TB, Gelrud A, Forsmark CE, Banks PA, Slivka A, Wilcox CM, Whitcomb DC, Yadav D
Institution:University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Journal:Am J Gastroenterol. 2017 Apr;112(4):633-642. doi: 10.1038/ajg.2017.42. Epub 2017 Feb 28.

10:Comparative Efficacy of Bilateral Thoracoscopic Splanchnicectomy for Intractable Pain Secondary to Pancreatic Cancer vs Chronic Pancreatitis.
Authors:Bhutiani N, Cheadle GA, Bahr MH, Vitale GC
Institution:Department of Surgery, University of Louisville, Louisville, KY. address:
Journal:J Am Coll Surg. 2017 Apr;224(4):566-571. doi: 10.1016/j.jamcollsurg.2016.12.048. Epub 2017 Jan 29.

11:Early Experience with Laparoscopic Frey Procedure for Chronic Pancreatitis: a Case Series and Review of Literature.
Authors:Kilburn DJ, Chiow AKH, Leung U, Siriwardhane M, Cavallucci DJ, Bryant R, O'Rourke NA
Institution:Hepatopancreatobiliary Unit, Department of Surgery, Royal Brisbane Hospital, Brisbane, Queensland, 4029, Australia. Singapore, Singapore. Brisbane, Queensland, 4029, Australia. Brisbane, Queensland, 4029, Australia. Brisbane, Queensland, 4029, Australia. Brisbane, Queensland, 4029, Australia. Brisbane, Queensland, 4029, Australia. Queensland, 4066, Australia.
Journal:J Gastrointest Surg. 2017 May;21(5):904-909. doi: 10.1007/s11605-016-3343-4. Epub 2016 Dec 26.

12:Telephone-Based Mindfulness Therapy Intervention for Patients with Chronic Pancreatitis.
Authors:Aivaliotis VI, Lee Y, Zia J, Wassef W, Abramson M, Park W
Institution:Department of Medicine, Stanford Hospital, Stanford, CA, USA. WA, USA.
Journal:Dig Dis Sci. 2017 Feb;62(2):502-509. doi: 10.1007/s10620-016-4389-6. Epub 2016 Dec 8.

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