Chronic Pancreatitis
October 2020 Issue

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Chronic Pancreatitis abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Chronic Pancreatitis. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Chronic Pancreatitis. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Chronic Pancreatitis every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content, Inc.

1:Chronic pancreatitis.
Authors:Beyer G, Habtezion A, Werner J, Lerch MM, Mayerle J
Institution:Medical Department II, University Hospital, LMU Munich, Munich, Germany. Electronic address:
Journal:Lancet. 2020 Aug 15;396(10249):499-512. doi: 10.1016/S0140-6736(20)31318-0.

2:High-Dose Prednisone for Treatment of Autoimmune Pancreatitis in a Patient with Coronavirus Disease 2019 (COVID-19) due to Infection with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
Authors:Liaquat H, Shupp B, Kapoor S, Matin A
Institution:Department of Gastroenterology, St. Luke's University Health Network, Bethlehem, PA, USA.
Journal:Am J Case Rep. 2020 Jul 21;21:e926475. doi: 10.12659/AJCR.926475.

3:Frequency of Care Fragmentation and Its Impact on Outcomes in Acute and Chronic Pancreatitis in a Nationally Representative Sample.
Authors:Qayed E, Mulki R
Institution:From the Department of Medicine, Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia.
Journal:South Med J. 2020 May;113(5):254-260. doi: 10.14423/SMJ.0000000000001094.

4:Laparoscopic Beger procedure for the treatment of chronic pancreatitis: a single-centre first experience.
Authors:Cai H, Cai Y, Wang X, Peng B
Institution:Department of Pancreatic Surgery, West China Hospital, Sichuan University, No. 37, Guo Xue Xiang, Chengdu, 610041, Sichuan, China.
Journal:BMC Surg. 2020 Apr 29;20(1):84. doi: 10.1186/s12893-020-00750-7.

5:The use of pancreatic enzyme replacement therapy in patients with a diagnosis of chronic pancreatitis and pancreatic cancer in the US is infrequent and inconsistent.
Authors:Forsmark CE, Tang G, Xu H, Tuft M, Hughes SJ, Yadav D
Institution:Division of Gastroenterology, Hepatology, and Nutrition, University of Florida, Gainesville, FL, USA. Division of Gastroenterology and Hepatology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Journal:Aliment Pharmacol Ther. 2020 May;51(10):958-967. doi: 10.1111/apt.15698. Epub 2020 Apr 6.

6:Standards for reporting on surgery for chronic pancreatitis: a report from the International Study Group for Pancreatic Surgery (ISGPS).
Authors:Siriwardena AK, Windsor J, Zyromski N, Marchegiani G, Radenkovic D, Morgan C, Passas I, Olah A, Conlon KC, Smith M, Busch O, Baltatzis M, Besselink MG, Vollmer C, Castillo CF, Friess H, Garcea G, Burmeister S, Hackert T, Lillemoe KD, Schulick R, Shrikhande SV, Smith A, Gianotti L, Falconi M, Adams D, Adham M, Andersson R, Del Chiaro M, Devar J, Jegatheeswaran S, van Santvoort H, Khatkov I, Izbicki J, B├╝chler M, Neoptolemos JP, Bassi C, Dervenis C
Institution:Department of Surgery, Regional Hepato-Pancreato-Biliary Unit, Manchester Royal Infirmary, United Kingdom. Electronic address: Department of Surgery, Metropolitan Hospital, Athens, Greece.
Journal:Surgery. 2020 Jul;168(1):101-105. doi: 10.1016/j.surg.2020.02.007. Epub 2020 Mar 14.

7:CT and MR features that can help to differentiate between focal chronic pancreatitis and pancreatic cancer.
Authors:Srisajjakul S, Prapaisilp P, Bangchokdee S
Institution:Division of Diagnostic Radiology, Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkoknoi, Bangkok, 10700, Thailand. Department of Internal Medicine, Pathum Thani Hospital, 7 Ladlumkaew-Patumthani Road, Muang District, Pathum Thani, 12000, Thailand.
Journal:Radiol Med. 2020 Apr;125(4):356-364. doi: 10.1007/s11547-019-01132-7. Epub 2020 Jan 13.

8:30-Day outcomes and predictors of complications after Puestow procedure.
Authors:Napolitano M, Brody F, Lee KB, Rosenfeld E, Chen S, Murillo-Berlioz AE, Amdur R
Institution:Department of Surgery, Washington D.C. Veterans Affairs Medical Center, Washington D.C., USA; Department of Surgery, George Washington University Hospital, Washington D.C., USA.
Journal:Am J Surg. 2020 Aug;220(2):372-375. doi: 10.1016/j.amjsurg.2019.12.024. Epub 2019 Dec 25.

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