Carcinoid Tumors
December 2017 Issue

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Carcinoid Tumors abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Carcinoid Tumors. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Carcinoid Tumors. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Carcinoid Tumors every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content, Inc.

1:External Validation of a Prognostic Model of Survival for Resected Typical Bronchial Carcinoids.
Authors:Cattoni M, Vallieres E, Brown LM, Sarkeshik AA, Margaritora S, Siciliani A, Imperatori A, Rotolo N, Farjah F, Wandell G, Costas K, Mann C, Hubka M, Kaplan S, Farivar AS, Aye RW, Louie BE
Institution:Division of Thoracic Surgery, Swedish Cancer Institute, Seattle, Washington. Center, Sacramento, California. Center, Sacramento, California. Italy. Italy. Seattle, Washington. Seattle, Washington. Washington. Seattle, Washington. Seattle, Washington. Electronic address:
Journal:Ann Thorac Surg. 2017 Oct;104(4):1215-1220. doi: 10.1016/j.athoracsur.2017.05.019. Epub 2017 Aug 16.

2:Adjuvant Chemotherapy Does Not Confer Superior Survival in Patients With Atypical Carcinoid Tumors.
Authors:Anderson KL Jr, Mulvihill MS, Speicher PJ, Yerokun BA, Gulack BC, Nussbaum DP, Harpole DH Jr, D'Amico TA, Berry MF, Hartwig MG
Institution:Duke University School of Medicine, Duke University Medical Center, Durham, North Carolina. Electronic address: Stanford, California. Carolina.
Journal:Ann Thorac Surg. 2017 Oct;104(4):1221-1230. doi: 10.1016/j.athoracsur.2017.05.011. Epub 2017 Jul 29.

3:Carcinoid heart disease.
Authors:Hassan SA, Banchs J, Iliescu C, Dasari A, Lopez-Mattei J, Yusuf SW
Institution:Department of Cardiology, Division of Medicine, MD Anderson Cancer Center, Houston, Texas, USA.; Department of Gastrointestinal Medical Oncology, Division of Cancer Medicine, MD Anderson Cancer Center, Houston, Texas, USA.
Journal:Heart. 2017 Oct;103(19):1488-1495. doi: 10.1136/heartjnl-2017-311261. Epub 2017 Jun 8.

4:Phase III Prospective Randomized Comparison Trial of Depot Octreotide Plus Interferon Alfa-2b Versus Depot Octreotide Plus Bevacizumab in Patients With Advanced Carcinoid Tumors: SWOG S0518.
Authors:Yao JC, Guthrie KA, Moran C, Strosberg JR, Kulke MH, Chan JA, LoConte N, McWilliams RR, Wolin EM, Mattar B, McDonough S, Chen H, Blanke CD, Hochster HS
Institution:James C. Yao and Cesar Moran, MD Anderson Cancer Center, Houston, TX; Katherine A. Guthrie and Shannon McDonough, Fred Hutchinson Cancer Research Center, Seattle, WA; Jonathan R. Strosberg, H. Lee Moffitt Cancer Center, Tampa, FL; Matthew H. Kulke and Jennifer A. Chan, Dana Farber Cancer Institute, Boston, MA; Noelle LoConte, University of Wisconsin, Carbone Cancer Center, Madison, WI; Robert R. McWilliams, Mayo Clinic College of Medicine, Rochester, MN; Edward M. Wolin, University of Kentucky, Lexington, KY; Edward M. Wolin, Montifiore Einstein Cancer Center, New York, NY; Bassam Mattar, Wichita NCORP/Cancer Center of Kansas, Wichita, KS; Helen Chen, NCI Cancer Therapy Evaluation Program, Bethesda, MD; Charles D. Blanke, Oregon Health & Science University, Portland, OR; and Howard S. Hochster, Yale Cancer Center, New Haven, CT.
Journal:J Clin Oncol. 2017 May 20;35(15):1695-1703. doi: 10.1200/JCO.2016.70.4072. Epub 2017 Apr 6.

5:National Rise of Primary Pancreatic Carcinoid Tumors: Comparison to Functional and Nonfunctional Pancreatic Neuroendocrine Tumors.
Authors:Kasumova GG, Tabatabaie O, Eskander MF, Tadikonda A, Ng SC, Tseng JF
Institution:Surgical Outcomes Analysis and Research, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA. Electronic address:
Journal:J Am Coll Surg. 2017 Jun;224(6):1057-1064. doi: 10.1016/j.jamcollsurg.2016.11.014. Epub 2016 Dec 10.

6:Advances in the Diagnosis and Management of Well-Differentiated and Intermediate-Differentiated Neuroendocrine Tumors of the Lung.
Authors:Wolin EM
Institution:Montefiore Einstein Center for Cancer Care, Bronx, NY. Electronic address:
Journal:Chest. 2017 May;151(5):1141-1146. doi: 10.1016/j.chest.2016.06.018. Epub 2016 Jun 29.

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What Our Customers Are Saying...

"The MediFocus Guidebook on Carcinoid Tumors helped me prepare for my operation. It was reassuring to be able to communicate with my surgeon and the consulting doctors having knowledge about my condition."
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