Carcinoid Tumors
April 2018 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Carcinoid Tumors abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Carcinoid Tumors. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Carcinoid Tumors. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Carcinoid Tumors every 3 months. Thank you for your ongoing subscription to this publication.

Sincerely,
Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Subcutaneous metastasis of a pulmonary carcinoid tumor: A case report.
Authors:Linhas R, Tente D, China N, Conde S, Barroso A
Institution:Department of Pulmonology. Gaia/Espinho, Vila Nova de Gaia, Portugal. Gaia/Espinho, Vila Nova de Gaia, Portugal.
Journal:Medicine (Baltimore). 2018 Jan;97(2):e9415. doi: 10.1097/MD.0000000000009415.

2:Extent of Resection and Lymph Node Assessment for Clinical Stage T1aN0M0 Typical Carcinoid Tumors.
Authors:Brown LM, Cooke DT, Jett JR, David EA
Institution:Section of General Thoracic Surgery, University of California, Davis Health, Sacramento, California. Electronic address: lmbrown@ucdavis.edu. Sacramento, California. Sacramento, California; Heart Lung Vascular Center, David Grant Medical Center, Travis AFB, California.
Journal:Ann Thorac Surg. 2018 Jan;105(1):207-213. doi: 10.1016/j.athoracsur.2017.07.049. Epub 2017 Nov 11.

3:Efficacy and safety of long-acting pasireotide or everolimus alone or in combination in patients with advanced carcinoids of the lung and thymus (LUNA): an open-label, multicentre, randomised, phase 2 trial.
Authors:Ferolla P, Brizzi MP, Meyer T, Mansoor W, Mazieres J, Do Cao C, Lena H, Berruti A, Damiano V, Buikhuisen W, Gronbaek H, Lombard-Bohas C, Grohe C, Minotti V, Tiseo M, De Castro J, Reed N, Gislimberti G, Singh N, Stankovic M, Oberg K, Baudin E
Institution:Department of Medical Oncology, Multidisciplinary NET Group, Umbria Regional Cancer Network and University of Perugia, Perugia, Italy. Electronic address: pferolla@gmail.com. London, London, UK. UK. Netherlands. Denmark. France.
Journal:Lancet Oncol. 2017 Dec;18(12):1652-1664. doi: 10.1016/S1470-2045(17)30681-2. Epub 2017 Oct 23.

4:Telotristat ethyl: proof of principle and the first oral agent in the management of well-differentiated metastatic neuroendocrine tumor and carcinoid syndrome diarrhea.
Authors:Masab M, Saif MW
Institution:Albert Einstein Medical Center, Philadelphia, PA, USA. Experimental Therapeutics, Tufts Medical Center, Tufts University School of Medicine, 800 Washington Street, Boston, MA, 02111, USA. wsaif@tuftsmedicalcenter.org.
Journal:Cancer Chemother Pharmacol. 2017 Dec;80(6):1055-1062. doi: 10.1007/s00280-017-3462-y. Epub 2017 Oct 19.

5:Histologically Proven Myocardial Carcinoid Metastases: The Value of Multimodality Imaging.
Authors:Studer Bruengger AA, Wechalekar K, Khattar R, Rosen SD, Robertus JL, Chau I, Morganstein D, Rosendahl U, Lyon A, Mohiaddin R
Institution:NIHR Cardiovascular Biomedical Research Unit, Royal Brompton and Harefield NHS Trust, London, UK; Department of Cardiology, City Hospital Triemli, Zurich, Switzerland.; NIHR Cardiovascular Biomedical Research Unit, Royal Brompton and Harefield NHS Trust, London, UK; Imperial College London, National Heart and Lung Institute, London, UK. Electronic address: r.mohiaddin@rbht.nhs.uk.; Imperial College London, National Heart and Lung Institute, London, UK; Department of Pathology, Royal Brompton and Harefield NHS Trust, London, UK.; Department of Medicine, Royal Marsden NHS Foundation Trust, London, UK.; Imperial College London, National Heart and Lung Institute, London, UK; Department of Medicine, Royal Marsden NHS Foundation Trust, London, UK; Department of Endocrinology, Chelsea and Westminster NHS Trust, London, UK.
Journal:Can J Cardiol. 2017 Oct;33(10):1336.e9-1336.e12. doi: 10.1016/j.cjca.2017.06.007. Epub 2017 Jun 16.

6:Carcinoid heart disease.
Authors:Hassan SA, Banchs J, Iliescu C, Dasari A, Lopez-Mattei J, Yusuf SW
Institution:Department of Cardiology, Division of Medicine, MD Anderson Cancer Center, Houston, Texas, USA.; Department of Gastrointestinal Medical Oncology, Division of Cancer Medicine, MD Anderson Cancer Center, Houston, Texas, USA.
Journal:Heart. 2017 Oct;103(19):1488-1495. doi: 10.1136/heartjnl-2017-311261. Epub 2017 Jun 8.

7:Investigation on Computed Tomography Features of Primary Thymic Atypical Carcinoid Tumors.
Authors:Kan X, Wang P, Gong Z, Gao F, Zhang Y, Ge Y
Institution:From the Departments of *Radiology and daggerPathology, Zhengzhou University People's Hospital, Zhengzhou, China.
Journal:J Comput Assist Tomogr. 2017 Nov/Dec;41(6):990-994. doi: 10.1097/RCT.0000000000000615.

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What Our Customers Are Saying...

"The MediFocus Guidebook on Carcinoid Tumors helped me prepare for my operation. It was reassuring to be able to communicate with my surgeon and the consulting doctors having knowledge about my condition."
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