Polycystic Kidney Disease
January 2017 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Polycystic Kidney Disease abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Polycystic Kidney Disease. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Polycystic Kidney Disease. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Polycystic Kidney Disease every 3 months. Thank you for your ongoing subscription to this publication.

Sincerely,
Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Copeptin levels and kidney function in ADPKD: case-control study.
Authors:Corradi V, Martino F, Gastaldon F, Scalzotto E, Caprara C, Fortunato A, Pinaffo G, Marchetti C, Fabbi F, Giavarina D, Ferrari F, Rosner MH, Ronco C
Journal:Clin Nephrol. 2016 Sep;86(9):147-53. doi: 10.5414/CN108894.

2:Clinical Outcome of Simultaneous Native Nephrectomy and Kidney Transplantation in Patients With Autosomal Dominant Polycystic Kidney Disease.
Authors:Kim JH, Chae SY, Bae HJ, Kim JI, Moon IS, Choi BS, Park CW, Yang CW, Kim YS, Chung BH
Institution:Transplant Research Center, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea; Division of Nephrology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. Electronic address: chungbh@catholic.ac.kr.; Transplant Research Center, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea; Department of Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Journal:Transplant Proc. 2016 Apr;48(3):840-3. doi: 10.1016/j.transproceed.2015.08.047.

3:Screening for Unruptured Intracranial Aneurysms in Autosomal Dominant Polycystic Kidney Disease: A Survey of 420 Nephrologists.
Authors:Flahault A, Trystram D, Fouchard M, Knebelmann B, Nataf F, Joly D
Institution:Universite Paris-Descartes; Faculte de Medecine; AP-HP; Service de Nephrologie, Hopital Necker-Enfants Malades, Paris, France. Hospitalier Sainte-Anne, Paris, France. Hopital Necker-Enfants Malades, Paris, France. Hopital Necker-Enfants Malades, Paris, France. Hospitalier Sainte-Anne, Paris, France. Hopital Necker-Enfants Malades, Paris, France.
Journal:PLoS One. 2016 Apr 7;11(4):e0153176. doi: 10.1371/journal.pone.0153176. eCollection 2016.

4:Recommendations for the use of tolvaptan in autosomal dominant polycystic kidney disease: a position statement on behalf of the ERA-EDTA Working Groups on Inherited Kidney Disorders and European Renal Best Practice.
Authors:Gansevoort RT, Arici M, Benzing T, Birn H, Capasso G, Covic A, Devuyst O, Drechsler C, Eckardt KU, Emma F, Knebelmann B, Le Meur Y, Massy ZA, Ong AC, Ortiz A, Schaefer F, Torra R, Vanholder R, Wiecek A, Zoccali C, Van Biesen W
Institution:Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.; Department of Nephrology, Hacettepe University Faculty of Medicine, Ankara, Turkey.; Department II of Internal Medicine and Centre for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.; Department of Renal Medicine, Aarhus University Hospital, Aarhus, Denmark Department of Biomedicine, Aarhus University, Aarhus, Denmark.; Department of Nephrology, Second University of Naples, Naples, Italy.
Journal:Nephrol Dial Transplant. 2016 Mar;31(3):337-48. doi: 10.1093/ndt/gfv456. Epub 2016 Jan 29.

5:Kidney Disease Progression in Autosomal Recessive Polycystic Kidney Disease.
Authors:Dell KM, Matheson M, Hartung EA, Warady BA, Furth SL
Institution:Center for Pediatric Nephrology, Cleveland Clinic Children's, Department of Pediatrics, Case Western Reserve University, Cleveland, OH. Electronic address: Katherine.Dell@case.edu.
Journal:J Pediatr. 2016 Apr;171:196-201.e1. doi: 10.1016/j.jpeds.2015.12.079. Epub 2016 Jan 28.

6:Long-term functional results of aspiration and sclerotherapy with ethanol in patients with autosomal dominant polycystic kidney disease: a non-randomized pilot clinical study.
Authors:Kucuk EV, Tahra A, Bindayi A, Suceken FY, Onol FF, Boylu U
Institution:Clinic of Urology, Umraniye Training and Research Hospital, Adem Yavuz cd. No. 1, 34766, Istanbul, Turkey. eyupveli@gmail.com.
Journal:Int Urol Nephrol. 2016 Apr;48(4):457-63. doi: 10.1007/s11255-015-1211-x. Epub 2016 Jan 12.

7:Endovascular Treatment of Intracranial Aneurysms in Patients With Autosomal Dominant Polycystic Kidney Disease.
Authors:Jung SC, Kim CH, Ahn JH, Cho YD, Kang HS, Cho WS, Kim JE, Ahn C, Han MH
Institution:*Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea; double daggerDepartment of Neurology, Myongji Hospital, Goyang, Republic of Korea; section signDepartment of Neurosurgery, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Republic of Korea; paragraph signDepartments of Radiology, ||Neurosurgery, and #Internal Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Journal:Neurosurgery. 2016 Mar;78(3):429-35; discussion 435. doi: 10.1227/NEU.0000000000001068.

8:The PROPKD Score: A New Algorithm to Predict Renal Survival in Autosomal Dominant Polycystic Kidney Disease.
Authors:Cornec-Le Gall E, Audrezet MP, Rousseau A, Hourmant M, Renaudineau E, Charasse C, Morin MP, Moal MC, Dantal J, Wehbe B, Perrichot R, Frouget T, Vigneau C, Potier J, Jousset P, Guillodo MP, Siohan P, Terki N, Sawadogo T, Legrand D, Menoyo-Calonge V, Benarbia S, Besnier D, Longuet H, Ferec C, Le Meur Y
Institution:Department of Nephrology, University Hospital, Brest, France; European University of Brittany, Brest, France; National Institute of Health and Medical Sciences, INSERM U1078, Brest, France; Department of Molecular Genetics, University Hospital, Brest, France; Medical Sciences, INSERM U1078, Brest, France; Department of Molecular Genetics, University Hospital, Brest, France; EFS Bretagne, Brest, France. of Brittany, Brest, France; yannick.lemeur@chu-brest.fr.
Journal:J Am Soc Nephrol. 2016 Mar;27(3):942-51. doi: 10.1681/ASN.2015010016. Epub 2015 Jul 6.

9:Pregnancy outcomes in autosomal dominant polycystic kidney disease: a case-control study.
Authors:Wu M, Wang D, Zand L, Harris PC, White WM, Garovic VD, Kermott CA
Institution:a Department of Cardiovascular Diseases , Guang`anmen Hospital, China Academy of Chinese Medical Sciences , Beijing , People's Republic of China .
Journal:J Matern Fetal Neonatal Med. 2016 Mar;29(5):807-12. doi: 10.3109/14767058.2015.1019458. Epub 2015 Mar 10.

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What Our Customers Are Saying...

"Last year my brother and his daughter were diagnosed with PKD. We had no idea what this disease was, if there was a cure, or how it would affect my family. There seemed to be very little information about PKD. Then I found the MediFocus Guidebook on Polycystic Kidney Disease. What a tremendous help! It has answered many questions and has given us some hope. Thank you."
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