Parkinson's Disease
June 2017 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Parkinson's Disease abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Parkinson's Disease. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Parkinson's Disease. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Parkinson's Disease every 3 months. Thank you for your ongoing subscription to this publication.

Sincerely,
Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Tobacco Use, Oral Health, and Risk of Parkinson's Disease.
Authors:Liu Z, Roosaar A, Axell T, Ye W
Journal:Am J Epidemiol. 2017 Apr 1;185(7):538-545. doi: 10.1093/aje/kww146.

2:Risk factors for early psychosis in PD: insights from the Parkinson's Progression Markers Initiative.
Authors:Ffytche DH, Pereira JB, Ballard C, Chaudhuri KR, Weintraub D, Aarsland D
Institution:KCL-PARCOG Group, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK. Neuroscience, King's College London, London, UK. Stockholm, Sweden. College London, London, UK. College London, London, UK. Neuroscience Institute, King's College London, London, UK. College London, London, UK. Pennsylvania, Philadelphia, Pennsylvania, USA. Pennsylvania, Philadelphia, Pennsylvania, USA. (PADRECC and MIRECC), Philadelphia Veterans Affairs Medical Centre, Philadelphia, Pennsylvania, USA. College London, London, UK. Neuroscience, King's College London, London, UK.
Journal:J Neurol Neurosurg Psychiatry. 2017 Apr;88(4):325-331. doi: 10.1136/jnnp-2016-314832.

3:Clinical manifestations of nonmotor symptoms in 1021 Japanese Parkinson's disease patients from 35 medical centers.
Authors:Maeda T, Shimo Y, Chiu SW, Yamaguchi T, Kashihara K, Tsuboi Y, Nomoto M, Hattori N, Watanabe H, Saiki H
Institution:Division of Neurology and Gerontology, Department of Internal Medicine, School of Medicine, Iwate Medical University, 19-1 Uchimaru, Morioka, Iwate 020-8505, Japan; Department of Neurology and Movement Disorder Research, Research Institute for Brain and Blood Vessels-Akita, 6-10 Senshukubotamachi, Akita 010-0874, Japan. Electronic address: maeda@iwate-med.ac.jp. Bunkyo-ku, Tokyo 113-8431, Japan. Electronic address: yshimo@juntendo.ac.jp. Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan. Electronic address: chiu@med.tohoku.ac.jp. Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan. Electronic address: yamaguchi@med.tohoku.ac.jp. 703-8265, Japan. Electronic address: kkashi@kyokuto.or.jp. Maidashi, Higashi-ku, Fukuoka City, 812-8582, Japan. Electronic address: tsuboi@cis.fukuoka-u.ac.jp. School of Medicine, 454 Shizukawa, Tohon, Ehime 791-0295, Japan. Electronic address: nomoto@m.ehime-u.ac.jp. Bunkyo-ku, Tokyo 113-8431, Japan. Electronic address: nhattori@juntendo.ac.jp. 464-8602, Japan. Electronic address: nabe@med.nagoya-u.ac.jp. Institute, 2-4-20 Ohgimachi, Kita-ku, Osaka 530-8480, Japan. Electronic address: saiki@kuhp.kyoto-u.ac.jp.
Journal:Parkinsonism Relat Disord. 2017 May;38:54-60. doi: 10.1016/j.parkreldis.2017.02.024. Epub 2017 Feb 21.

4:Parkinson's Disease: From Pathogenesis to Pharmacogenomics.
Authors:Cacabelos R
Institution:EuroEspes Biomedical Research Center, Institute of Medical Science and Genomic Medicine, 15165-Bergondo, Corunna, Spain. rcacabelos@euroespes.com.
Journal:Int J Mol Sci. 2017 Mar 4;18(3). pii: E551. doi: 10.3390/ijms18030551.

5:A comprehensive overview of the neuropsychiatry of Parkinson's disease: A review.
Authors:Khan MA, Quadri SA, Tohid H
Institution:Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Journal:Bull Menninger Clin. 2017 Winter;81(1):53-105. doi: 10.1521/bumc.2017.81.1.53.

6:Parkinsonian gait improves with bilateral subthalamic nucleus deep brain stimulation during cognitive multi-tasking.
Authors:Chenji G, Wright ML, Chou KL, Seidler RD, Patil PG
Institution:Surgical Therapies Improving Movement Program, University of Michigan, Ann Arbor, MI, USA; Department of Neurosurgery, University of Michigan, Ann Arbor, MI, USA. MI, USA; School of Kinesiology, University of Michigan, Ann Arbor, MI, USA. MI, USA; Department of Neurology, University of Michigan, Ann Arbor, MI, USA; Department of Neurosurgery, University of Michigan, Ann Arbor, MI, USA. Kinesiology, University of Michigan, Ann Arbor, MI, USA. MI, USA; Department of Neurology, University of Michigan, Ann Arbor, MI, USA; Department of Neurosurgery, University of Michigan, Ann Arbor, MI, USA. Electronic address: pgpatil@med.umich.edu.
Journal:Parkinsonism Relat Disord. 2017 May;38:72-79. doi: 10.1016/j.parkreldis.2017.02.028. Epub 2017 Feb 24.

7:Acupuncture as Adjuvant Therapy for Sleep Disorders in Parkinson's Disease.
Authors:Aroxa FH, Gondim IT, Santos EL, Coriolano MD, Asano AG, Asano NM
Institution:Academic of Medicine graduation of Federal University of Pernambuco - Recife, Pernambuco (PE), Brazil. Recife (PE), Brazil. Recife (PE), Brazil. Recife (PE), Brazil. Recife (PE), Brazil. Brazil. Electronic address: nadjaasano@gmail.com.
Journal:J Acupunct Meridian Stud. 2017 Jan;10(1):33-38. doi: 10.1016/j.jams.2016.12.007. Epub 2017 Jan 11.

8:Timed Light Therapy for Sleep and Daytime Sleepiness Associated With Parkinson Disease: A Randomized Clinical Trial.
Authors:Videnovic A, Klerman EB, Wang W, Marconi A, Kuhta T, Zee PC
Institution:Department of Neurology, Massachusetts General Hospital, Boston 2Division of Sleep Medicine, Harvard Medical School, Boston, Massachusetts. Massachusetts3Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
Journal:JAMA Neurol. 2017 Apr 1;74(4):411-418. doi: 10.1001/jamaneurol.2016.5192.

9:Which patients discontinue? Issues on Levodopa/carbidopa intestinal gel treatment: Italian multicentre survey of 905 patients with long-term follow-up.
Authors:Sensi M, Cossu G, Mancini F, Pilleri M, Zibetti M, Modugno N, Quatrale R, Tamma F, Antonini A
Institution:Department of Neurology, Azienda Ospedaliera Universitaria Arcispedale S.Anna, Ferrara, Italy. giovannicossu@aob.it. Arcugnano, Vicenza, Italy. Turin, Italy.
Journal:Parkinsonism Relat Disord. 2017 May;38:90-92. doi: 10.1016/j.parkreldis.2017.02.020. Epub 2017 Feb 21.

10:Exploring risk factors for stuttering development in Parkinson disease after deep brain stimulation.
Authors:Picillo M, Vincos GB, Sammartino F, Lozano AM, Fasano A
Institution:Centre for Neurodegenerative Diseases (CEMAND), Department of Medicine and Surgery, Neuroscience Section, University of Salerno, Salerno, Italy. Universidad la Sabana, Bogota, Colombia. Toronto Western Hospital, University of Toronto, Canada. Toronto Western Hospital, University of Toronto, Canada; Krembil Research Institute, Toronto, Ontario, Canada. Movement Disorders Clinic, Toronto Western Hospital and Division of Neurology, University of Toronto, Toronto, Ontario, Canada; Edmond J. Safra Program in Parkinson's Disease, Toronto Western Hospital and Division of Neurology, University of Toronto, Toronto, Ontario, Canada. Electronic address: alfonso.fasano@gmail.com.
Journal:Parkinsonism Relat Disord. 2017 May;38:85-89. doi: 10.1016/j.parkreldis.2017.02.015. Epub 2017 Feb 20.

11:Opicapone for the treatment of Parkinson's disease.
Authors:Rodrigues FB, Ferreira JJ
Institution:a Laboratory of Clinical Pharmacology and Therapeutics, Faculty of Medicine , University of Lisbon , Lisboa , Portugal. Medicine , University of Lisbon , Lisbon , Portugal. , London , UK. University of Lisbon , Lisboa , Portugal. Medicine , University of Lisbon , Lisbon , Portugal.
Journal:Expert Opin Pharmacother. 2017 Mar;18(4):445-453. doi: 10.1080/14656566.2017.1294683. Epub 2017 Feb 22.

12:Reduced cognitive function in patients with Parkinson disease and obstructive sleep apnea.
Authors:Mery VP, Gros P, Lafontaine AL, Robinson A, Benedetti A, Kimoff RJ, Kaminska M
Institution:From Clinica Alemana de Santiago (V.P.M.), Facultad de Medicina, Universidad del Desarrollo, Santiago, Chile; and Respiratory Division & Sleep Laboratory (P.G., A.R., R.J.K., M.K.), Montreal Neurological Hospital (A.-L.L.), Departments of Medicine and Epidemiology, Biostatistics & Occupational Health (A.B.), and Respiratory Epidemiology and Clinical Research Unit, Research Institute (A.B., M.K.), McGill University Health Centre, Montreal, Canada. vmery@alemana.cl. Desarrollo, Santiago, Chile; and Respiratory Division & Sleep Laboratory (P.G., A.R., R.J.K., M.K.), Montreal Neurological Hospital (A.-L.L.), Departments of Medicine and Epidemiology, Biostatistics & Occupational Health (A.B.), and Respiratory Epidemiology and Clinical Research Unit, Research Institute (A.B., M.K.), McGill University Health Centre, Montreal, Canada. Desarrollo, Santiago, Chile; and Respiratory Division & Sleep Laboratory (P.G., A.R., R.J.K., M.K.), Montreal Neurological Hospital (A.-L.L.), Departments of Medicine and Epidemiology, Biostatistics & Occupational Health (A.B.), and Respiratory Epidemiology and Clinical Research Unit, Research Institute (A.B., M.K.), McGill University Health Centre, Montreal, Canada. Desarrollo, Santiago, Chile; and Respiratory Division & Sleep Laboratory (P.G., A.R., R.J.K., M.K.), Montreal Neurological Hospital (A.-L.L.), Departments of Medicine and Epidemiology, Biostatistics & Occupational Health (A.B.), and Respiratory Epidemiology and Clinical Research Unit, Research Institute (A.B., M.K.), McGill University Health Centre, Montreal, Canada. Desarrollo, Santiago, Chile; and Respiratory Division & Sleep Laboratory (P.G., A.R., R.J.K., M.K.), Montreal Neurological Hospital (A.-L.L.), Departments of Medicine and Epidemiology, Biostatistics & Occupational Health (A.B.), and Respiratory Epidemiology and Clinical Research Unit, Research Institute (A.B., M.K.), McGill University Health Centre, Montreal, Canada. Desarrollo, Santiago, Chile; and Respiratory Division & Sleep Laboratory (P.G., A.R., R.J.K., M.K.), Montreal Neurological Hospital (A.-L.L.), Departments of Medicine and Epidemiology, Biostatistics & Occupational Health (A.B.), and Respiratory Epidemiology and Clinical Research Unit, Research Institute (A.B., M.K.), McGill University Health Centre, Montreal, Canada. Desarrollo, Santiago, Chile; and Respiratory Division & Sleep Laboratory (P.G., A.R., R.J.K., M.K.), Montreal Neurological Hospital (A.-L.L.), Departments of Medicine and Epidemiology, Biostatistics & Occupational Health (A.B.), and Respiratory Epidemiology and Clinical Research Unit, Research Institute (A.B., M.K.), McGill University Health Centre, Montreal, Canada.
Journal:Neurology. 2017 Mar 21;88(12):1120-1128. doi: 10.1212/WNL.0000000000003738. Epub 2017 Feb 22.

13:Nonmotor symptoms in de novo Parkinson disease comparing to normal aging.
Authors:Bago Rozankovic P, Rozankovic M, Vucak Novosel L, Stojic M
Institution:Department of Neurology, University Hospital Dubrava, Avenija Gojka Suska 6, 10000 Zagreb, Croatia. Electronic address: petrabago@yahoo.com. 10000 Zagreb, Croatia. 10000 Zagreb, Croatia. 10000 Zagreb, Croatia.
Journal:Clin Neurol Neurosurg. 2017 Apr;155:7-11. doi: 10.1016/j.clineuro.2017.02.002. Epub 2017 Feb 11.

14:Walking on four limbs: A systematic review of Nordic Walking in Parkinson disease.
Authors:Bombieri F, Schena F, Pellegrini B, Barone P, Tinazzi M, Erro R
Institution:Department of Neuroscience, Biomedicine and Movement Sciences, Universita di Verona, Verona, Italy. Verona, Verona, Italy. Verona, Verona, Italy; CeRiSM (Research Centre of Mountain Sport and Health), University of Verona, Rovereto, Italy. Surgery, Neuroscience Section, University of Salerno, Salerno, Italy. Verona, Verona, Italy. Electronic address: michele.tinazzi@univr.it. Surgery, Neuroscience Section, University of Salerno, Salerno, Italy; Sobell Department of Motor Neuroscience and Movement Disorders, University College London (UCL) Institute of Neurology, London, United Kingdom.
Journal:Parkinsonism Relat Disord. 2017 May;38:8-12. doi: 10.1016/j.parkreldis.2017.02.004. Epub 2017 Feb 6.

15:Comorbid conditions associated with Parkinson's disease: A longitudinal and comparative study with Alzheimer disease and control subjects.
Authors:Santos Garcia D, Suarez Castro E, Exposito I, de Deus T, Tunas C, Aneiros A, Lopez Fernandez M, Nunez Arias D, Bermudez Torres M
Institution:Section of Neurology, Complejo Hospitalario Universitario de Ferrol (CHUF), Hospital A. Marcide, Ferrol, A Coruna, Spain. Electronic address: diegosangar@yahoo.es. Hospital A. Marcide, Ferrol, A Coruna, Spain. Hospital A. Marcide, Ferrol, A Coruna, Spain. Hospital A. Marcide, Ferrol, A Coruna, Spain. Hospital A. Marcide, Ferrol, A Coruna, Spain. Hospital A. Marcide, Ferrol, A Coruna, Spain. Hospital A. Marcide, Ferrol, A Coruna, Spain. Hospital Naval, Ferrol, A Coruna, Spain. (CHUF), Ferrol, A Coruna, Spain.
Journal:J Neurol Sci. 2017 Feb 15;373:210-215. doi: 10.1016/j.jns.2016.12.046. Epub 2016 Dec 29.

16:Neuropsychiatric symptoms, behavioural disorders, and quality of life in Parkinson's disease.
Authors:Balestrino R, Martinez-Martin P
Institution:Department of Neuroscience "Rita Levi Montalcini", University of Turin, Via Cherasco 15, 10124 Torino, Italy. Madrid, Spain. Electronic address: pmartinez@isciii.es.
Journal:J Neurol Sci. 2017 Feb 15;373:173-178. doi: 10.1016/j.jns.2016.12.060. Epub 2016 Dec 28.

17:Conversion to carbidopa and levodopa extended-release (IPX066) followed by its extended use in patients previously taking controlled-release carbidopa-levodopa for advanced Parkinson's disease.
Authors:Tetrud J, Nausieda P, Kreitzman D, Liang GS, Nieves A, Duker AP, Hauser RA, Farbman ES, Ellenbogen A, Hsu A, Kell S, Khanna S, Rubens R, Gupta S
Institution:The Parkinson's Institute and Clinical Center, 675 Almanor Ave, Sunnyvale, CA 94085, USA. Electronic address: jtetrud@stanford.edu. WI 53233, USA. Electronic address: nausiedamd@parkcent.com. Rd, Commack, NY 11725, USA. Electronic address: PDMDCLI@aol.com. 94085, USA. Electronic address: graceliangmd@gmail.com. Electronic address: Anette_Nieves@munroeregional.com. address: dukeraa@ucmail.uc.edu. address: rhauser@health.usf.edu. 89102, USA. Electronic address: efarbman@medicine.nevada.edu. USA. Electronic address: aellenbogen@comcast.net. address: annhsu@aol.com. address: skell@impaxlabs.com. address: skhanna@impaxlabs.com. address: rrubens@impaxlabs.com. address: sgupta@impaxlabs.com.
Journal:J Neurol Sci. 2017 Feb 15;373:116-123. doi: 10.1016/j.jns.2016.11.047. Epub 2016 Nov 23.

18:Spotlight on opicapone as an adjunct to levodopa in Parkinson's disease: design, development and potential place in therapy.
Authors:Annus A, Vecsei L
Institution:Department of Neurology, Faculty of Medicine, Albert Szent-Gyorgyi Clinical Center, University of Szeged. Center, University of Szeged; MTA-SZTE Neuroscience Research Group, Szeged, Hungary.
Journal:Drug Des Devel Ther. 2017 Jan 9;11:143-151. doi: 10.2147/DDDT.S104227. eCollection 2017.

19:Natural course of mild cognitive impairment in Parkinson disease: A 5-year population-based study.
Authors:Pedersen KF, Larsen JP, Tysnes OB, Alves G
Institution:From the Norwegian Centre for Movement Disorders (K.F.P., G.A.); Department of Neurology (K.F.P., G.A.) and Memory Clinic (K.F.P., G.A.), Stavanger University Hospital; Network for Medical Sciences (J.P.L.), University of Stavanger; and Department of Neurology (O.-B.T.), Haukeland University Hospital, Bergen, Norway. pekf@sus.no. Neurology (K.F.P., G.A.) and Memory Clinic (K.F.P., G.A.), Stavanger University Hospital; Network for Medical Sciences (J.P.L.), University of Stavanger; and Department of Neurology (O.-B.T.), Haukeland University Hospital, Bergen, Norway. Neurology (K.F.P., G.A.) and Memory Clinic (K.F.P., G.A.), Stavanger University Hospital; Network for Medical Sciences (J.P.L.), University of Stavanger; and Department of Neurology (O.-B.T.), Haukeland University Hospital, Bergen, Norway. Neurology (K.F.P., G.A.) and Memory Clinic (K.F.P., G.A.), Stavanger University Hospital; Network for Medical Sciences (J.P.L.), University of Stavanger; and Department of Neurology (O.-B.T.), Haukeland University Hospital, Bergen, Norway.
Journal:Neurology. 2017 Feb 21;88(8):767-774. doi: 10.1212/WNL.0000000000003634. Epub 2017 Jan 20.

20:Clinical effectiveness of acupuncture on Parkinson disease: A PRISMA-compliant systematic review and meta-analysis.
Authors:Lee SH, Lim S
Institution:aDepartment of Applied Korean Medicine, College of Korean Medicine, Graduate School, Kyung Hee University bResearch Group of Pain and Neuroscience, WHO Collaborating Center for Traditional Medicine, East-West Medical Research Institute cDepartment of Meridian and Acupoint, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.
Journal:Medicine (Baltimore). 2017 Jan;96(3):e5836. doi: 10.1097/MD.0000000000005836.

21:Preclinical and Potential Applications of Common Western Herbal Supplements as Complementary Treatment in Parkinson's Disease.
Authors:Morgan LA, Grundmann O
Institution:a Department of Medicinal Chemistry , College of Pharmacy, University of Florida , Gainesville , FL , USA. , Gainesville , FL , USA.
Journal:J Diet Suppl. 2017 Jul 4;14(4):453-466. doi: 10.1080/19390211.2016.1263710. Epub 2017 Jan 17.

22:Opicapone as Adjunct to Levodopa Therapy in Patients With Parkinson Disease and Motor Fluctuations: A Randomized Clinical Trial.
Authors:Lees AJ, Ferreira J, Rascol O, Poewe W, Rocha JF, McCrory M, Soares-da-Silva P
Institution:Reta Lila Weston Institute, University College London, London, England. Recherche Medicale (INSERM) and University Hospital of Toulouse, Toulouse, France4Department of Neurosciences, INSERM and University Hospital of Toulouse, Toulouse, France. Coronado, Portugal. Coronado, Portugal8Department of Pharmacology and Therapeutics, University Porto, Porto, Portugal.
Journal:JAMA Neurol. 2017 Feb 1;74(2):197-206. doi: 10.1001/jamaneurol.2016.4703.

23:Assessment of Safety and Efficacy of Safinamide as a Levodopa Adjunct in Patients With Parkinson Disease and Motor Fluctuations: A Randomized Clinical Trial.
Authors:Schapira AH, Fox SH, Hauser RA, Jankovic J, Jost WH, Kenney C, Kulisevsky J, Pahwa R, Poewe W, Anand R
Institution:Department of Clinical Neurosciences, University College London Institute of Neurology, London, United Kingdom. University of Toronto, Toronto, Ontario, Canada. Universitat Oberta de Catalunya, Barcelona, Spain.
Journal:JAMA Neurol. 2017 Feb 1;74(2):216-224. doi: 10.1001/jamaneurol.2016.4467.

24:The efficacy and safety of coenzyme Q10 in Parkinson's disease: a meta-analysis of randomized controlled trials.
Authors:Zhu ZG, Sun MX, Zhang WL, Wang WW, Jin YM, Xie CL
Institution:Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, China. University, Wenzhou, 35000, China. University, Wenzhou, 325000, China. Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325027, China. Children's Hospital of Wenzhou Medical University, Wenzhou, 325027, China. 69365560@qq.com. University, Wenzhou, 325000, China. xiechenglong1987@sina.com.
Journal:Neurol Sci. 2017 Feb;38(2):215-224. doi: 10.1007/s10072-016-2757-9. Epub 2016 Nov 9.

25:Cognitive Effects of Rasagiline in Mild-to-Moderate Stage Parkinson's Disease Without Dementia.
Authors:Frakey LL, Friedman JH
Institution:From the Memorial Hospital of Rhode Island-Medical Rehabilitation, Pawtucket, R.I. (LLF); and the Alpert Medical School of Brown University, Providence, R.I. (JHF). R.I. (LLF); and the Alpert Medical School of Brown University, Providence, R.I. (JHF).
Journal:J Neuropsychiatry Clin Neurosci. 2017 Winter;29(1):22-25. doi: 10.1176/appi.neuropsych.15050118. Epub 2016 Nov 10.

26:Osteopathic manipulation as a complementary approach to Parkinson's disease: A controlled pilot study.
Authors:DiFrancisco-Donoghue J, Apoznanski T, de Vries K, Jung MK, Mancini J, Yao S
Institution:Department of Osteopathic Medicine, College of Osteopathic Medicine, New York Institute of Technology (NYITCOM), Old Westbury, NY, USA. Westbury, NY, USA. Westbury, NY, USA. USA. Institute of Technology (NYITCOM), Old Westbury, NY, USA. Institute of Technology (NYITCOM), Old Westbury, NY, USA.
Journal:NeuroRehabilitation. 2017;40(1):145-151. doi: 10.3233/NRE-161400.

27:Dance therapy improves motor and cognitive functions in patients with Parkinson's disease.
Authors:de Natale ER, Paulus KS, Aiello E, Sanna B, Manca A, Sotgiu G, Leali PT, Deriu F
Institution:Department of Biomedical Sciences, University of Sassari, Sassari, Italy. Italy. Sassari, Italy. Sassari, Italy. Sassari, Italy.
Journal:NeuroRehabilitation. 2017;40(1):141-144. doi: 10.3233/NRE-161399.

28:Impulse control behaviors and subthalamic deep brain stimulation in Parkinson disease.
Authors:Merola A, Romagnolo A, Rizzi L, Rizzone MG, Zibetti M, Lanotte M, Mandybur G, Duker AP, Espay AJ, Lopiano L
Institution:Department of Neurology, Gardner Family Center for Parkinson's Disease and Movement Disorders, University of Cincinnati (UC), 260 Stetson Street, Suite 4244, Cincinnati, OH, 45219, USA. merolaae@ucmail.uc.edu. Cherasco 15, 10124, Turin, Italy. Cherasco 15, 10124, Turin, Italy. Cherasco 15, 10124, Turin, Italy. Cherasco 15, 10124, Turin, Italy. Cherasco 15, 10124, Turin, Italy. University of Cincinnati (UC), Cincinnati, OH, USA. Movement Disorders, University of Cincinnati (UC), 260 Stetson Street, Suite 4244, Cincinnati, OH, 45219, USA. Movement Disorders, University of Cincinnati (UC), 260 Stetson Street, Suite 4244, Cincinnati, OH, 45219, USA. Cherasco 15, 10124, Turin, Italy.
Journal:J Neurol. 2017 Jan;264(1):40-48. doi: 10.1007/s00415-016-8314-x. Epub 2016 Oct 19.

29:Benefits of Exercise on the Executive Functions in People with Parkinson Disease: A Controlled Clinical Trial.
Authors:de Oliveira RT, Felippe LA, Bucken Gobbi LT, Barbieri FA, Christofoletti G
Institution:From the Graduate Program in Health and Development, Universidade Federal de Mato Grosso do Sul, UFMS, Campo Grande, Mato Grosso do Sul (RTO, LAF, GC); Universidade Estadual Paulista, UNESP, Rio Claro (LTBG, FAB); and Universidade Estadual Paulista, UNESP, Bauru, Sao Paulo, Brazil (FAB).
Journal:Am J Phys Med Rehabil. 2017 May;96(5):301-306. doi: 10.1097/PHM.0000000000000612.

30:Management of Parkinson's disease in Ayurveda: Medicinal plants and adjuvant measures.
Authors:Pathak-Gandhi N, Vaidya AD
Institution:Medical Research Centre - Kasturba Health Society, 17 K Desai Road, Mumbai, India. Electronic address: namyata@gmail.com. India. Electronic address: ashokdbv@gmail.com.
Journal:J Ethnopharmacol. 2017 Feb 2;197:46-51. doi: 10.1016/j.jep.2016.08.020. Epub 2016 Aug 17.

31:Deep Brain Stimulation Target Selection for Parkinson's Disease.
Authors:Honey CR, Hamani C, Kalia SK, Sankar T, Picillo M, Munhoz RP, Fasano A, Panisset M
Institution:1Division of Neurosurgery,University of British Columbia,Vancouver,British Columbia. of Alberta,Edmonton,Alberta. Program in Parkinson's Disease,Toronto Western Hospital,University Health Network,Toronto,Ontario. Program in Parkinson's Disease,Toronto Western Hospital,University Health Network,Toronto,Ontario. Program in Parkinson's Disease,Toronto Western Hospital,University Health Network,Toronto,Ontario. Montreal Health Centre,Montreal,Quebec,Canada.
Journal:Can J Neurol Sci. 2017 Jan;44(1):3-8. doi: 10.1017/cjn.2016.22. Epub 2016 Mar 15.

32:Minimally invasive motor cortex stimulation for Parkinson's disease.
Authors:Lavano A, Guzzi G, DE Rose M, Romano M, Della Torre A, Vescio G, Deodato F, Lavano F, Volpentesta G
Institution:Department of Neurosurgery, "Magna Graecia" University, Catanzaro, Italy - lavano@unicz.it.
Journal:J Neurosurg Sci. 2017 Feb;61(1):77-87. Epub 2015 Apr 17.

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Russelsheim, Germany


"I found your Guidebook on Parkinson's to be very informative for me, the patient, and for my husband. I am in the process of changing my medication and the book explained more to me than the doctor attempted to. I am now more aware of what to expect. It also offered valuable advice for the caregiver. Thank you."
M.N.
Palm Spring, California


"The Medifocus Guide to Parkinson's Disease was useful, informative, and allowed me to grasp the current fundamentals of treatment. I have recommended it to two of my ex-patients whom I know will find it readable and helpful to their needs."
G.B.
Research Triangle Park, NC



  
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