Parkinson's Disease
September 2018 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Parkinson's Disease abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Parkinson's Disease. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Parkinson's Disease. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Parkinson's Disease every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:The long-term efficacy of STN vs GPi deep brain stimulation for Parkinson disease: A meta-analysis.
Authors:Peng L, Fu J, Ming Y, Zeng S, He H, Chen L
Institution:Department of Neurosurgery. Luzhou, China.
Journal:Medicine (Baltimore). 2018 Aug;97(35):e12153. doi: 10.1097/MD.0000000000012153.

2:Meta-analysis of the adverse events associated with extended-release versus standard immediate-release pramipexole in Parkinson disease.
Authors:Shen Z, Kong D
Institution:Department of Pharmacy, Yongchuan Hospital, Chongqing Medical University, Chongqing, China.
Journal:Medicine (Baltimore). 2018 Aug;97(34):e11316. doi: 10.1097/MD.0000000000011316.

3:Pharmacological interventions for anxiety in Parkinson's disease sufferers.
Authors:Sawada H, Umemura A, Kohsaka M, Tomita S, Park K, Oeda T, Yamamoto K
Institution:a Department of Neurology & Clinical Research Center , Utano National Hospital , Kyoto , Japan. Kyoto , Japan. Kyoto , Japan. Kyoto , Japan. Kyoto , Japan. Kyoto , Japan. Kyoto , Japan.
Journal:Expert Opin Pharmacother. 2018 Jul;19(10):1071-1076. doi: 10.1080/14656566.2018.1485650. Epub 2018 Jun 25.

4:A noninterventional study evaluating the effectiveness of rotigotine and levodopa combination therapy in younger versus older patients with Parkinson's disease.
Authors:Woitalla D, Dunac A, Safavi A, Ceravolo MG, Gomez Esteban JC, Pavese N, Asgharnejad M, Joeres L, Schuller JC, Chaudhuri KR
Institution:a Department of Neurology , St. Joseph Hospital, Ruhr-University , Bochum , Germany. University , Ancona , Italy. Clinical Neuroscience Institute, King's College London and King's College Hospital , London , UK.
Journal:Expert Opin Pharmacother. 2018 Jun;19(9):937-945. doi: 10.1080/14656566.2018.1480721. Epub 2018 Jun 19.

5:Long-term management of Parkinson's disease using levodopa combinations.
Authors:Muller T, Mohr JD
Institution:a Department of Neurology , St. Joseph Hospital Berlin-Weissensee , Berlin , Germany. Germany.
Journal:Expert Opin Pharmacother. 2018 Jun;19(9):1003-1011. doi: 10.1080/14656566.2018.1484108. Epub 2018 Jun 18.

6:Deep Brain Stimulation for Parkinson Disease in the Philippines: Outcomes of the Philippine Movement Disorder Surgery Center.
Authors:Diestro JDB, Vesagas TS, Teleg RA, Aguilar JA, Anlacan JP, Jamora RDG
Institution:Department of Neurosciences, Philippine General Hospital, University of the Philippines Manila, Manila, Philippines. Juan City, Philippines. Juan City, Philippines; Section of Neurology, Department of Medicine, National Kidney and Transplant Institute, Quezon City, Philippines. Juan City, Philippines. Juan City, Philippines; Department of Psychiatry and Behavioral Medicine, College of Medicine, Philippine General Hospital, University of the Philippines Manila, Manila, Philippines. Juan City, Philippines; Department of Neurosciences, College of Medicine - Philippine General Hospital, University of the Philippines Manila, Manila, Philippines; Movement Disorder Service and Section of Neurology, Institute for Neurosciences, St. Luke's Medical Center, Quezon City and Global City, Philippines. Electronic address: rgjamora@up.edu.ph.
Journal:World Neurosurg. 2018 Jul;115:e650-e658. doi: 10.1016/j.wneu.2018.04.125. Epub 2018 Apr 28.

7:Increased risk of overactive bladder in patients with idiopathic Parkinson's disease: Insight from a nationwide population-based cohort study.
Authors:Lin FY, Yang YC, Lin CL, Lee LJ
Institution:Department of Neurology, China Medical University Hospital, China Medical University School of Medicine, Taichung, Taiwan. University School of Medicine, Taichung, Taiwan. Taiwan. Institutes, Miaoli, Taiwan. Health, National Taiwan University, Taipei, Taiwan. University, Kaohsiung, Taiwan.
Journal:PLoS One. 2018 Mar 2;13(3):e0193783. doi: 10.1371/journal.pone.0193783. eCollection 2018.

8:Pharmacological interventions for psychosis in Parkinson's disease patients.
Authors:Friedman JH
Institution:a Movement Disorders Program , Butler Hospital , Providence , RI , USA. Providence , RI , USA.
Journal:Expert Opin Pharmacother. 2018 Apr;19(5):499-505. doi: 10.1080/14656566.2018.1445721. Epub 2018 Mar 1.

9:Real life evaluation of safinamide effectiveness in Parkinson's disease.
Authors:Mancini F, Di Fonzo A, Lazzeri G, Borellini L, Silani V, Lacerenza M, Comi C
Institution:Department of Neurology-Stroke Unit and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy. Francesca.mancini@tin.it. Ferrari" Center, Neuroscience Section, Department of Pathophysiology and Transplantation, Universita Degli Studi di Milano, Milan, Italy. Ferrari" Center, Neuroscience Section, Department of Pathophysiology and Transplantation, Universita Degli Studi di Milano, Milan, Italy. Policlinico, Universita degli Studi di Milano, Milan, Italy. Istituto Auxologico Italiano, Milan, Italy. Ferrari" Centre - Centre for Neurotechnology and Brain Therapeutics, Department of Pathophysiology and Transplantation, Universita degli Studi di Milano, Milan, Italy. Italy.
Journal:Neurol Sci. 2018 Apr;39(4):733-739. doi: 10.1007/s10072-018-3272-y. Epub 2018 Feb 13.

10:Fatigue in Parkinson's disease: concepts and clinical approach.
Authors:Nassif DV, Pereira JS
Institution:Department of Neurology, Pedro Ernesto University Hospital, State University of Rio de Janeiro, Rio de Janeiro, Brazil. Rio de Janeiro, Rio de Janeiro, Brazil.
Journal:Psychogeriatrics. 2018 Mar;18(2):143-150. doi: 10.1111/psyg.12302. Epub 2018 Feb 6.

11:The effects of transdermal rotigotine on non-motor symptoms of Parkinson's disease: a multicentre, observational, retrospective, post-marketing study.
Authors:Valldeoriola F, Salvador A, Gomez-Arguelles JM, Marey J, Moya M, Ayuga A, Ramirez F
Institution:a Neurology Department , Hospital Clinico De Barcelona , Barcelona , Spain. Spain.
Journal:Int J Neurosci. 2018 Apr;128(4):369-375. doi: 10.1080/00207454.2017.1387111. Epub 2017 Dec 17.

12:Deep Brain Stimulation in Patients with Parkinson's Disease: Effect on Psychiatric Symptoms and Quality of Life.
Authors:Seijo Zazo E, Fernandez FS, Liebana ES, Ayala AS, Aragoneses BL, Campa JMT, Portilla PG, Vega MA
Institution:Psychiatry Department, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain. Asturias, Spain. Asturias, Spain. Asturias, Spain. Asturias, Spain.
Journal:J Neurol Surg A Cent Eur Neurosurg. 2018 Mar;79(2):130-138. doi: 10.1055/s-0037-1606354. Epub 2017 Sep 29.

13:Use of e-mail for Parkinson's disease consultations: Are answers just a clic away?
Authors:Viedma-Guiard E, Aguero P, Crespo-Araico L, Estevez-Fraga C, Sanchez-Diez G, Lopez-Sendon JL, Aviles-Olmos I, Garcia-Ribas G, Palacios Romero ML, Masjuan Vallejo J, Martinez-Castrillo JC, Alonso-Canovas A
Institution:Unidad de Trastornos del Movimiento, Servicio de Neurologia, Hospital Universitario Ramon y Cajal, IRYCIS, Universidad de Alcala, Madrid, Espana. Electronic address: elenaviedmag@gmail.com.; Direccion de Continuidad Asistencial, Hospital Universitario Ramon y Cajal, IRYCIS, Universidad de Alcala, Madrid, Espana.
Journal:Neurologia. 2018 Mar;33(2):107-111. doi: 10.1016/j.nrl.2016.05.020. Epub 2016 Jul 26.

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