Trigeminal Neuralgia
August 2017 Issue

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Trigeminal Neuralgia abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Trigeminal Neuralgia. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Trigeminal Neuralgia. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Trigeminal Neuralgia every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content, Inc.

1:Botulinum neurotoxin type A for the treatment of pain: not just in migraine and trigeminal neuralgia.
Authors:Sandrini G, De Icco R, Tassorelli C, Smania N, Tamburin S
Institution:C. Mondino National Institute of Neurology Foundation, IRCCS, Pavia, Italy. Verona, Piazzale Scuro 10, I-37134, Verona, Italy. Verona, Italy.
Journal:J Headache Pain. 2017 Dec;18(1):38. doi: 10.1186/s10194-017-0744-z. Epub 2017 Mar 21.

2:Safety and efficacy of a Nav1.7 selective sodium channel blocker in patients with trigeminal neuralgia: a double-blind, placebo-controlled, randomised withdrawal phase 2a trial.
Authors:Zakrzewska JM, Palmer J, Morisset V, Giblin GM, Obermann M, Ettlin DA, Cruccu G, Bendtsen L, Estacion M, Derjean D, Waxman SG, Layton G, Gunn K, Tate S
Institution:Facial Pain Unit, Division of Diagnostic, Surgical and Medical Sciences, Eastman Dental Hospital, University College London Hospitals NHS Foundation Trust/University College London, London, UK. Electronic address: Essen, Germany; Center for Neurology, Asklepios Hospitals Schildautal, Seesen, Germany. University of Zurich, Zurich, Switzerland. University of Copenhagen, Nordre Ringvej 67, 2600 Glostrup, Denmark. Yale University School of Medicine, and Veterans Affairs Medical Center, West Haven, CT, USA. Yale University School of Medicine, and Veterans Affairs Medical Center, West Haven, CT, USA.
Journal:Lancet Neurol. 2017 Apr;16(4):291-300. doi: 10.1016/S1474-4422(17)30005-4. Epub 2017 Feb 17.

3:Trigeminal nerve block with alcohol for medically intractable classic trigeminal neuralgia: long-term clinical effectiveness on pain.
Authors:Han KR, Chae YJ, Lee JD, Kim C
Institution:Kichan Pain Clinic, Suwon, Korea.
Journal:Int J Med Sci. 2017 Jan 1;14(1):29-36. doi: 10.7150/ijms.16964. eCollection 2017.

4:Topical Review: Potential Use of Botulinum Toxin in the Management of Painful Posttraumatic Trigeminal Neuropathy.
Authors:Moreau N, Dieb W, Descroix V, Svensson P, Ernberg M, Boucher Y
Journal:J Oral Facial Pain Headache. 2017 Winter;31(1):7-18. doi: 10.11607/ofph.1753.

5:Options in treating trigeminal neuralgia: Experience with 195 patients.
Authors:Hitchon PW, Holland M, Noeller J, Smith MC, Moritani T, Jerath N, He W
Institution:Department of Neurosurgery, University of Iowa Carver College of Medicine, Iowa City, IA, United States. Electronic address: City, IA, United States. City, IA, United States. Iowa City, IA, United States. City, IA, United States. City, IA, United States. Newark, NJ, United States.
Journal:Clin Neurol Neurosurg. 2016 Oct;149:166-70. doi: 10.1016/j.clineuro.2016.08.016. Epub 2016 Aug 17.

Authors:ul Haq N, Ali M, Khan HM, Ishaq M, Khattak MI
Journal:J Ayub Med Coll Abbottabad. 2016 Jan-Mar;28(1):52-5.

7:Microvascular decompression for elderly patients with trigeminal neuralgia.
Authors:Phan K, Rao PJ, Dexter M
Institution:Department of Neurosurgery, Westmead Hospital, Hawkesbury Road, Westmead, NSW 2145, Australia; Faculty of Medicine, University of Sydney, Sydney, NSW, Australia. Electronic address:; Department of Neurosurgery, Westmead Hospital, Hawkesbury Road, Westmead, NSW 2145, Australia; Department of Surgery, University of New South Wales, Sydney, NSW, Australia.
Journal:J Clin Neurosci. 2016 Jul;29:7-14. doi: 10.1016/j.jocn.2015.11.027. Epub 2016 Mar 2.

8:Trigeminal neuralgia (part II): Factors affecting early pharmacotherapeutic outcome.
Authors:Benoliel R, Zini A, Khan J, Almoznino G, Sharav Y, Haviv Y
Institution:Rutgers School of Dental Medicine, Rutgers State University of New Jersey, USA University-Hadassah, Israel. University-Hadassah, Israel Department of Oral Medicine, Oral and Maxillofacial Center, Medical Corps, Israel Defense Forces, Israel. University-Hadassah, Israel. University-Hadassah, Israel.
Journal:Cephalalgia. 2016 Jul;36(8):747-59. doi: 10.1177/0333102415611406. Epub 2015 Oct 9.

9:Repeat Gamma-Knife Radiosurgery for Refractory or Recurrent Trigeminal Neuralgia with Consideration About the Optimal Second Dose.
Authors:Park SC, Kwon do H, Lee do H, Lee JK
Institution:Department of Neurosurgery, Asan Medical Center, Seoul, Korea.; Department of Neurosurgery, Asan Medical Center, Seoul, Korea; Department of Neurosurgery, College of Medicine, University of Ulsan, Seoul, Korea. Electronic address:
Journal:World Neurosurg. 2016 Feb;86:371-83. doi: 10.1016/j.wneu.2015.08.056. Epub 2015 Sep 2.

For a FREE PREVIEW of the Medifocus Guidebook on Trigeminal Neuralgia click here

To purchase a copy of the COMPLETE Medifocus Guidebook on Trigeminal Neuralgia click here

To subscribe to additional FREE Medifocus Digest Alert on other disease/condition areas click here

Get the Medifocus Guidebook on Trigeminal Neuralgia...
at a Special 20% Discount

Medifocus Guidebook on Trigeminal Neuralgia

Updated: June 23, 2017
124 Pages

This one of a kind Guidebook offers:

  • Answers to your critical health questions including the latest treatments, clinical trials, and expert research.
  • High Quality, Professional level information you can trust and understand culled from the latest peer-reviewed journals.
  • Timely, up to date content with free guidebook updates for 1 year.
  • A unique resource to find leading experts, institutions, and support organizations including contact information and hyperlinks.
  • Over 130,000 Guidebooks Sold
  • 100% Risk Free Money Back Guarantee


The Medifocus Guidebook on Trigeminal Neuralgia is available in the following two convenient formats:


Soft-cover book that is available for immediate shipping via either U.S. Priority Mail or International AirMail (outside the U.S.).

  • Regular List Price = $36.95
  • Less 20% Discount = - $7.40
  • Discounted Price = $29.55(excluding shipping & handling)

Order the Printed Guidebook


Available for immediate download as a PDF document.

  • Regular List Price = $27.95
  • Less 20% Discount = - $5.60
  • Discounted Price = $22.35

Order the Digital Guidebook

Order by Phone

Call Toll Free in the U.S.

From Outside the U.S.

You can also receive a 20% discount when you order your Guidebook by phone.

To receive your 20% discount, simply mention the Discount Coupon Code below to the customer service representative taking your order.

Discount Coupon Code for
Phone Orders


Coupon Expires: October 25, 2017

What Our Customers Are Saying...

"My 19 year old daughter is suffering from Trigeminal Neuralgia. The TN Guidebook was very informative - especially in pinpointing the symptoms and giving us resources on where to go for additional information and help from doctors. Thanks for putting all this information in one place and making it easy to read and use."
Milwaukee, Wisconsin

"I spent numerous hours in the library and on the Internet looking for information on trigeminal neuralgia. The MediFocus Guidebook on Trigeminal Neuralgia I purchased was the BEST and most detailed of the all the information I could find. I have referred to the Guidebook many times...thank you for offering it."
Phoenix, Arizona

"The MediFocus Guidebook on Trigeminal Neuralgia was very helpful and full of legitimate resources. The Guidebook described the various approaches to treatment in a detailed but very readable manner. It has provided me with the ammunition I needed to engage my doctor in a detailed discussion about my treatment options."
Birmingham, Alabama

Medifocus Digest Alert is published monthly by Medifocus, Inc.
6810 Park Heights Avenue, Suite C5, Baltimore, MD 21215 USA
Copyright © 2013 Medifocus, Inc. All rights reserved.