Trigeminal Neuralgia
October 2017 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Trigeminal Neuralgia abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Trigeminal Neuralgia. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Trigeminal Neuralgia. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Trigeminal Neuralgia every 3 months. Thank you for your ongoing subscription to this publication.

Sincerely,
Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Stereotactic Radiosurgery for Trigeminal Neuralgia Improves Patient-Reported Quality of Life and Reduces Depression.
Authors:Kotecha R, Miller JA, Modugula S, Barnett GH, Murphy ES, Reddy CA, Suh JH, Neyman G, Machado A, Nagel S, Chao ST
Institution:Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio.; Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio.; Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio; Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center, Cleveland Clinic, Cleveland, Ohio; Department of Neurosurgery, Neurological Institute, Cleveland Clinic, Cleveland, Ohio.; Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio; Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio; Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center, Cleveland Clinic, Cleveland, Ohio. Electronic address: chaos@ccf.org.; Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio; Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center, Cleveland Clinic, Cleveland, Ohio.
Journal:Int J Radiat Oncol Biol Phys. 2017 Aug 1;98(5):1078-1086. doi: 10.1016/j.ijrobp.2017.04.008. Epub 2017 Apr 11.

2:Gamma Knife Radiosurgery for Idiopathic Trigeminal Neuralgia: Does the Status of Offending Vessels Influence Pain Control or Side Effects?
Authors:Jung HH, Park CK, Jung NY, Kim M, Chang WS, Chang JW
Institution:Department of Neurosurgery, Brain Research Institute, Yonsei University College of Medicine, Seoul, Korea. Electronic address: jchang@yuhs.ac.
Journal:World Neurosurg. 2017 Aug;104:687-693. doi: 10.1016/j.wneu.2017.05.058. Epub 2017 May 19.

3:Stereotactic Radiosurgery as Initial Surgical Management for Elderly Patients with Trigeminal Neuralgia.
Authors:Cohen J, Mousavi SH, Faraji AH, Akpinar B, Monaco EA, Flickinger JC, Niranjan A, Lunsford LD
Institution:University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Journal:Stereotact Funct Neurosurg. 2017;95(3):158-165. doi: 10.1159/000468526. Epub 2017 May 13.

4:Computed Tomography in the Diagnosis of Classical Trigeminal Neuralgia.
Authors:Baliazin VA, Baliazina EV, Aksenov DP
Institution:From the *Department of Nervous Diseases and Neurosurgery, Rostov State Medical University, Rostov-on-Don, Russia; and daggerResearch Institute, NorthShore University HealthSystem, Evanston, IL.
Journal:J Comput Assist Tomogr. 2017 Jul/Aug;41(4):521-527. doi: 10.1097/RCT.0000000000000567.

5:Frameless Stereotactic Radiosurgery for Treatment of Multiple Sclerosis-Related Trigeminal Neuralgia.
Authors:Conti A, Pontoriero A, Iati G, Esposito F, Siniscalchi EN, Crimi S, Vinci S, Brogna A, De Ponte F, Germano A, Pergolizzi S, Tomasello F
Institution:Unit of Neurosurgery, Department of Biomedical and Dental Sciences and Morpho-Functional Imaging, University of Messina, Messina, Italy. Electronic address: alfredo.conti@unime.it.; Unit of Radiation Oncology, Department of Biomedical and Dental Sciences and Morpho-Functional Imaging, University of Messina, Messina, Italy.; Unit of Maxillo-Facial Surgery, Department of Biomedical and Dental Sciences and Morpho-Functional Imaging, University of Messina, Messina, Italy.; Unit of Neuroradiology, Department of Biomedical and Dental Sciences and Morpho-Functional Imaging, University of Messina, Messina, Italy.; Unit of Medical Physics, Department of Biomedical and Dental Sciences and Morpho-Functional Imaging, University of Messina, Messina, Italy.
Journal:World Neurosurg. 2017 Jul;103:702-712. doi: 10.1016/j.wneu.2017.04.102. Epub 2017 Apr 26.

6:Meta-Analysis on Safety and Efficacy of Microsurgical and Radiosurgical Treatment of Trigeminal Neuralgia.
Authors:Gubian A, Rosahl SK
Institution:Department of Neurosurgery, HELIOS Klinikum Erfurt, Erfurt, Germany. Electronic address: arthur.gubian@yahoo.com.
Journal:World Neurosurg. 2017 Jul;103:757-767. doi: 10.1016/j.wneu.2017.04.085. Epub 2017 Apr 20.

7:Safety of Superior Petrosal Vein Sacrifice During Microvascular Decompression of the Trigeminal Nerve.
Authors:Pathmanaban ON, O'Brien F, Al-Tamimi YZ, Hammerbeck-Ward CL, Rutherford SA, King AT
Institution:Manchester Skull Base Unit, Department of Neurosurgery, Manchester Centre for Clinical Neuroscience, Salford Royal Hospital, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom. Electronic address: omar.pathmanaban@manchester.ac.uk.
Journal:World Neurosurg. 2017 Jul;103:84-87. doi: 10.1016/j.wneu.2017.03.117. Epub 2017 Apr 2.

8:Trigeminal Neuralgia: Toward a Multimodal Approach.
Authors:Spina A, Mortini P, Alemanno F, Houdayer E, Iannaccone S
Institution:Department of Neurosurgery and Gamma Knife Radiosurgery, San Raffaele Scientific Institute, Vita-Salute University, Milan, Italy. Electronic address: spina.alfio@hsr.it.; Department of Clinical Neuroscience, Specialistic Neurorehabilitation of Neurological, Cognitive and Motor Disorders, San Raffaele Scientific Institute, Milan, Italy.
Journal:World Neurosurg. 2017 Jul;103:220-230. doi: 10.1016/j.wneu.2017.03.126. Epub 2017 Apr 2.

9:Trigeminal Neuralgia Completely Relieved After Stent-Assisted Coiling of a Superior Cerebellar Artery Aneurysm.
Authors:Di Stefano G, Limbucci N, Cruccu G, Renieri L, Truini A, Mangiafico S
Institution:Department of Neurology and Psychiatry, Sapienza University of Rome, Rome, Italy. Electronic address: andrea.truini@uniroma1.it.
Journal:World Neurosurg. 2017 May;101:812.e5-812.e9. doi: 10.1016/j.wneu.2017.03.082. Epub 2017 Mar 25.

10:Botulinum neurotoxin type A for the treatment of pain: not just in migraine and trigeminal neuralgia.
Authors:Sandrini G, De Icco R, Tassorelli C, Smania N, Tamburin S
Institution:C. Mondino National Institute of Neurology Foundation, IRCCS, Pavia, Italy. Verona, Piazzale Scuro 10, I-37134, Verona, Italy. Verona, Italy.
Journal:J Headache Pain. 2017 Dec;18(1):38. doi: 10.1186/s10194-017-0744-z. Epub 2017 Mar 21.

11:Linac-based stereotactic radiosurgery (SRS) in the treatment of refractory trigeminal neuralgia: Detailed description of SRS procedure and reported clinical outcomes.
Authors:Pokhrel D, Sood S, McClinton C, Saleh H, Badkul R, Jiang H, Stepp T, Camarata P, Wang F
Institution:Department of Radiation Oncology, The University of Kansas Cancer Center, Kansas City, KS, USA.; Department of Neurosurgery, The University of Kansas Cancer Center, Kansas City, KS, USA.
Journal:J Appl Clin Med Phys. 2017 Mar;18(2):136-143. doi: 10.1002/acm2.12057. Epub 2017 Feb 28.

12:Safety and efficacy of a Nav1.7 selective sodium channel blocker in patients with trigeminal neuralgia: a double-blind, placebo-controlled, randomised withdrawal phase 2a trial.
Authors:Zakrzewska JM, Palmer J, Morisset V, Giblin GM, Obermann M, Ettlin DA, Cruccu G, Bendtsen L, Estacion M, Derjean D, Waxman SG, Layton G, Gunn K, Tate S
Institution:Facial Pain Unit, Division of Diagnostic, Surgical and Medical Sciences, Eastman Dental Hospital, University College London Hospitals NHS Foundation Trust/University College London, London, UK. Electronic address: j.zakrzewska@ucl.ac.uk. Essen, Germany; Center for Neurology, Asklepios Hospitals Schildautal, Seesen, Germany. University of Zurich, Zurich, Switzerland. University of Copenhagen, Nordre Ringvej 67, 2600 Glostrup, Denmark. Yale University School of Medicine, and Veterans Affairs Medical Center, West Haven, CT, USA. Yale University School of Medicine, and Veterans Affairs Medical Center, West Haven, CT, USA.
Journal:Lancet Neurol. 2017 Apr;16(4):291-300. doi: 10.1016/S1474-4422(17)30005-4. Epub 2017 Feb 17.

13:Diagnosis and management for trigeminal neuralgia caused solely by venous compression.
Authors:Inoue T, Hirai H, Shima A, Suzuki F, Fukushima T, Matsuda M
Institution:Department of Neurosurgery, Subarukai Kotoh Kinen Hospital, 2-1 Hiramatsu-cho, Higashiohmi-shi, Shiga, 527-0134, Japan. takuro39@gmail.com.; Division of Neurosurgery, Duke University Medical Center, Durham, NC, USA.
Journal:Acta Neurochir (Wien). 2017 Apr;159(4):681-688. doi: 10.1007/s00701-017-3085-4. Epub 2017 Jan 20.

14:Delayed Development of Aneurysms Following Gamma Knife Surgery for Trigeminal Neuralgia: Report of 2 Cases.
Authors:Uchikawa H, Nishi T, Kaku Y, Goto T, Kuratsu JI, Yano S
Institution:Division of Neurosurgery, Saiseikai Kumamoto Hospital, Kumamoto, Japan. Electronic address: h.uchikawa.1223@gmail.com.
Journal:World Neurosurg. 2017 Mar;99:813.e13-813.e19. doi: 10.1016/j.wneu.2016.11.069. Epub 2016 Nov 24.

15:Trigeminal neuralgia due to venous neurovascular conflicts: outcome after microvascular decompression in a series of 55 consecutive patients.
Authors:Dumot C, Brinzeu A, Berthiller J, Sindou M
Institution:Neurosurgical Department, Hospital Pierre Wertheimer, University Lyon 1, Lyon, France. France. andrei.brinzeu@chu-lyon.fr. andrei.brinzeu@chu-lyon.fr. Neurochirurgie A, 59 Bd. Pinel, 69500, Bron, France. andrei.brinzeu@chu-lyon.fr. France. France.
Journal:Acta Neurochir (Wien). 2017 Feb;159(2):237-249. doi: 10.1007/s00701-016-2994-y. Epub 2016 Nov 5.

16:Radiosurgery for Secondary Trigeminal Neuralgia: Revisiting the Treatment Paradigm.
Authors:Chivukula S, Kim W, Zhuo X, Tenn S, Kaprealian T, DeSalles A, Pouratian N
Institution:Department of Neurological Surgery, University of California, Los Angeles, Los Angeles, California, USA. Electronic address: schivukula@mednet.ucla.edu. Angeles, California, USA. Angeles, California, USA. Angeles, California, USA. Angeles, California, USA. Angeles, California, USA. Angeles, California, USA; Department of Radiation Oncology, University of California, Los Angeles, Los Angeles, California, USA; Interdepartmental Program in Neuroscience, University of California, Los Angeles, Los Angeles, California, USA; Department of Bioengineering, University of California, Los Angeles, Los Angeles, California, USA; Brain Research Institute, University of California, Los Angeles, Los Angeles, California, USA.
Journal:World Neurosurg. 2017 Mar;99:288-294. doi: 10.1016/j.wneu.2016.09.087. Epub 2016 Oct 1.

17:Migraine-tic syndrome: Two further case reports.
Authors:Hinze S, Davies P, Astbury T, Lane R
Institution:1 Department of Neurology, Great Western Hospital, Swindon, UK. Northampton, UK. Northampton, UK.
Journal:Cephalalgia. 2017 Mar;37(3):290-293. doi: 10.1177/0333102416644436. Epub 2016 Jul 11.

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