Peripheral Neuropathy
May 2020 Issue

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Peripheral Neuropathy abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Peripheral Neuropathy. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Peripheral Neuropathy. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Peripheral Neuropathy every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content, Inc.

1:A systematic review and meta-analysis of the efficacy of acupuncture and electroacupuncture against chemotherapy-induced peripheral neuropathy.
Authors:Hwang MS, Lee HY, Choi TY, Lee JH, Ko YS, Jo DC, Do K, Lee JH, Park TY
Institution:3rd Division of Clinical Medicine, School of Korean Medicine, Pusan National University, Yangsan. Institute for Integrative Medicine, Catholic Kwandong University International St. Mary's Hospital, Incheon, Republic of Korea.
Journal:Medicine (Baltimore). 2020 Apr;99(17):e19837. doi: 10.1097/MD.0000000000019837.

2:Acupuncture as adjuvant therapy for diabetic foot: A protocol for systematic review.
Authors:Lee M, Li H, Liu D
Institution:Guangzhou University of Chinese Medicine, University Town of Guangzhou, Panyu District, Guangzhou City. Department of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, Futian District, Shenzhen City, Guangdong Province, China.
Journal:Medicine (Baltimore). 2020 Mar;99(12):e19502. doi: 10.1097/MD.0000000000019502.

3:The utility of a single simple question in the evaluation of patients with nondiabetic polyneuropathy.
Authors:Abraham A, Lovblom LE, Bril V
Institution:Neuromuscular Diseases Unit of the Department of Neurology, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. Ellen and Martin Prosserman Centre for Neuromuscular Diseases, Division of Neurology, Department of Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada.
Journal:Muscle Nerve. 2020 Apr;61(4):526-529. doi: 10.1002/mus.26802. Epub 2020 Jan 13.

4:Effect of serotonin-norepinephrine reuptake inhibitors for patients with chemotherapy-induced painful peripheral neuropathy: A meta-analysis.
Authors:Song SY, Ko YB, Kim H, Lee GW, Yang JB, Chang HK, Kwak SM, Jung J, Lee S, Lee SY, Yoo HJ
Institution:Department of Obstetrics & Gynecology, Chungnam National University School of Medicine, Daejeon.
Journal:Medicine (Baltimore). 2020 Jan;99(1):e18653. doi: 10.1097/MD.0000000000018653.

5:A population-based study of long-term outcome in treated chronic inflammatory demyelinating polyneuropathy.
Authors:Al-Zuhairy A, Sindrup SH, Andersen H, Jakobsen J
Institution:Department of Neurology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Journal:Muscle Nerve. 2020 Mar;61(3):316-324. doi: 10.1002/mus.26772. Epub 2020 Jan 1.

6:Prevention of chemotherapy-induced peripheral neuropathy: A review of recent findings.
Authors:Ibrahim EY, Ehrlich BE
Institution:Departments of Pharmacology and Cellular and Molecular Physiology, Yale University, New Haven, CT, 06510, USA. Electronic address: Departments of Pharmacology and Cellular and Molecular Physiology, Yale University, New Haven, CT, 06510, USA. Electronic address:
Journal:Crit Rev Oncol Hematol. 2020 Jan;145:102831. doi: 10.1016/j.critrevonc.2019.102831. Epub 2019 Nov 13.

7:A simple method of quantifying chemotherapy-induced peripheral neuropathy using PainVision PS-2100(®).
Authors:Saito M, Odajima S, Yokomizo R, Tabata J, Iida Y, Ueda K, Yanaihara N, Yamada K, Okamoto A
Institution:Department of Obstetrics and Gynecology, The Jikei University School of Medicine, Tokyo, Japan.
Journal:Asia Pac J Clin Oncol. 2020 Feb;16(1):80-85. doi: 10.1111/ajco.13293. Epub 2019 Nov 26.

8:The Biomechanics of Diabetes Mellitus and Limb Preservation.
Authors:Labovitz JM, Day D
Institution:Clinical Education and Graduate Services, College of Podiatric Medicine, Western University of Health Sciences, 309 East Second Street, Pomona, CA 91766, USA. Electronic address: College of Podiatric Medicine, Western University of Health Sciences, 309 East Second Street, Pomona, CA 91766, USA; Chino Valley Medical Center, Chino, CA 91710, USA.
Journal:Clin Podiatr Med Surg. 2020 Jan;37(1):151-169. doi: 10.1016/j.cpm.2019.08.011. Epub 2019 Oct 21.

9:Utility of electrodiagnostic studies in patients referred with a diagnosis of polyneuropathy.
Authors:Ginsberg MR, Morren JA
Institution:Neuromuscular Center, Neurological Institute-Cleveland Clinic, Cleveland, Ohio.
Journal:Muscle Nerve. 2020 Mar;61(3):288-292. doi: 10.1002/mus.26746. Epub 2019 Dec 11.

10:Bone and soft tissue infections in patients with diabetic foot.
Authors:Leone A, Vitiello C, Gullì C, Sikora AK, Macagnino S, Colosimo C
Institution:Fondazione Policlinico Universitario A. Gemelli, IRCCS, Universita Cattolica del Sacro Cuore (AL, CC), Largo A. Gemelli 1, 00168, Rome, Italy.
Journal:Radiol Med. 2020 Feb;125(2):177-187. doi: 10.1007/s11547-019-01096-8. Epub 2019 Oct 24.

11:Incidence and Risk Factors Associated With Ulcer Recurrence Among Patients With Diabetic Foot Ulcers Treated in a Multidisciplinary Setting.
Authors:Hicks CW, Canner JK, Mathioudakis N, Lippincott C, Sherman RL, Abularrage CJ
Institution:Diabetic Foot and Wound Service, The Johns Hopkins Hospital, Baltimore, Maryland; Division of Vascular Surgery and Endovascular Therapy, Department of Surgery, The Johns Hopkins Hospital, Baltimore, Ma
Journal:J Surg Res. 2020 Feb;246:243-250. doi: 10.1016/j.jss.2019.09.025. Epub 2019 Oct 11.

12:Nerve dysfunction leads to muscle morphological abnormalities in chronic inflammatory demyelinating polyneuropathy assessed by MRI.
Authors:Gilmore KJ, Fanous J, Doherty TJ, Kimpinski K, Rice CL
Institution:School of Kinesiology, Faculty of Health Science, London, Ontario, Canada.
Journal:Clin Anat. 2020 Jan;33(1):77-84. doi: 10.1002/ca.23473. Epub 2019 Oct 30.

13:Topical Recombinant Human Epidermal Growth Factor for Diabetic Foot Ulcers: A Meta-Analysis of Randomized Controlled Clinical Trials.
Authors:Yang Q, Zhang Y, Yin H, Lu Y
Institution:Trauma, Department of Orthopedics, The Second Hospital of Shanxi Medical University, Taiyuan, China.
Journal:Ann Vasc Surg. 2020 Jan;62:442-451. doi: 10.1016/j.avsg.2019.05.041. Epub 2019 Aug 5.

14:Clinical Utility of the Ankle-Brachial Index and Toe Brachial Index in Patients with Diabetic Foot Ulcers.
Authors:Ababneh M, Al Ayed MY, Robert AA, Al Dawish MA
Institution:Department of Endocrinology and Diabetes, Diabetes Treatment Center, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.
Journal:Curr Diabetes Rev. 2020;16(3):270-277. doi: 10.2174/1573399815666190531093238.

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What Our Customers Are Saying...

"This is the BEST informational and reference book pertaining to my long-time ailment 'Peripheral Neuropathy'. I have researched this relatively obscure subject for seven years. The MediFocus Guidebook on Peripheral Neuropathy is easy reading, concise, and contains great references."
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Midland, Texas

"I recently purchased your MediFocus Guidebook on Peripheral Neuropathy and found the information quite helpful in making decisions about the direction I wanted to take in dealing with my condition. Even after meeting with a Neurologist and being tested, I had many questions that he was unable to answer. We all have to take control of our own health care and the MediFocus Guidebook is a great tool for doing that."
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