Peripheral Neuropathy
August 2017 Issue

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Peripheral Neuropathy abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Peripheral Neuropathy. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Peripheral Neuropathy. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Peripheral Neuropathy every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content, Inc.

1:Effect of omega-3 supplementation on neuropathy in type 1 diabetes: A 12-month pilot trial.
Authors:Lewis EJH, Perkins BA, Lovblom LE, Bazinet RP, Wolever TMS, Bril V
Institution:From the Department of Nutritional Sciences (E.J.H.L., R.P.B., T.M.S.W.), Faculty of Medicine, University of Toronto; Leadership Sinai Centre for Diabetes (B.A.P., L.E.L.), Mount Sinai Hospital, Toronto; and Ellen and Martin Prosserman Centre for Neuromuscular Diseases (V.B.), Division of Neurology, University Health Network, Toronto, Canada.
Journal:Neurology. 2017 Jun 13;88(24):2294-2301. doi: 10.1212/WNL.0000000000004033. Epub 2017 May 17.

2:Chemotherapy-induced peripheral neuropathy: A current review.
Authors:Staff NP, Grisold A, Grisold W, Windebank AJ
Institution:Department of Neurology, Mayo Clinic, Rochester, MN. Austria.
Journal:Ann Neurol. 2017 Jun;81(6):772-781. doi: 10.1002/ana.24951. Epub 2017 Jun 5.

3:Update on Chemotherapy-Induced Peripheral Neuropathy.
Authors:Cioroiu C, Weimer LH
Institution:Neurological Institute of New York, Columbia University Medical Center, 710 W168th Street, New York, NY, 10032, USA. W168th Street, New York, NY, 10032, USA.
Journal:Curr Neurol Neurosci Rep. 2017 Jun;17(6):47. doi: 10.1007/s11910-017-0757-7.

4:Pharmacotherapy for diabetic peripheral neuropathy pain and quality of life: A systematic review.
Authors:Waldfogel JM, Nesbit SA, Dy SM, Sharma R, Zhang A, Wilson LM, Bennett WL, Yeh HC, Chelladurai Y, Feldman D, Robinson KA
Institution:From the Department of Pharmacy (J.M.W., S.A.N.), The Johns Hopkins Hospital; Department of Health Policy & Management (S.M.D., R.S., A.Z., L.M.W.), Johns Hopkins Bloomberg School of Public Health; Division of General Internal Medicine (W.L.B., K.A.R.) and Department of Physical Medicine & Rehabilitation (D.F.), Johns Hopkins University School of Medicine; Departments of Medicine, Epidemiology, and Oncology (H.-C.Y.), Division of General Internal Medicine, Johns Hopkins University, Baltimore, MD; and Department of Internal Medicine (Y.C.), Morehouse School of Medicine, Atlanta, GA.
Journal:Neurology. 2017 May 16;88(20):1958-1967. doi: 10.1212/WNL.0000000000003882. Epub 2017 Mar 24.

5:Prevalence of Peripheral Neuropathy and associated factors in HIV-infected patients.
Authors:Benevides ML, Filho SB, Debona R, Bergamaschi EN, Nunes JC
Institution:Division of Neuropathology, Universidade Federal de Santa Catarina (UFSC), Rua Professora Maria Flora Pausewang, Trindade, Florianopolis, Santa Catarina (SC), Brazil. Catarina (SC), Brazil. Florianopolis, Brazil. Florianopolis, Brazil. Professora Maria Flora Pausewang, Trindade, Florianopolis, Santa Catarina (SC), Brazil; Neurodiagnostic Brasil-Diagnosticos em Neuropatologia, Rua Santos Saraiva, Estreito, Florianopolis, Santa Catarina (SC), Brazil. Electronic address:
Journal:J Neurol Sci. 2017 Apr 15;375:316-320. doi: 10.1016/j.jns.2017.02.011. Epub 2017 Feb 8.

6:Potential application of the Kampo medicine goshajinkigan for prevention of chemotherapy-induced peripheral neuropathy.
Authors:Cascella M, Muzio MR
Institution:Division of Anesthesia, Department of Anesthesia and Pain Medicine, Istituto Nazionale Tumori "Fondazione G. Pascale"-IRCCS, via Mariano Semmola, Naples 80131, Italy. SUD, Torre del Greco, via Marconi, Naples 80059, Italy.
Journal:J Integr Med. 2017 Mar;15(2):77-87. doi: 10.1016/S2095-4964(17)60313-3.

7:Use of an alpha lipoic, methylsulfonylmethane and bromelain dietary supplement (Opera(R)) for chemotherapy-induced peripheral neuropathy management, a prospective study.
Authors:Desideri I, Francolini G, Becherini C, Terziani F, Delli Paoli C, Olmetto E, Loi M, Perna M, Meattini I, Scotti V, Greto D, Bonomo P, Sulprizio S, Livi L
Institution:Department of Clinical and Experimental Biomedical Sciences, University of Florence, Viale Morgagni 85, 50134, Florence, Italy.; Department of Radiation Oncology, Azienda Ospedaliero-Universitaria Careggi, University of Florence, Florence, Italy.
Journal:Med Oncol. 2017 Mar;34(3):46. doi: 10.1007/s12032-017-0907-4. Epub 2017 Feb 15.

8:Acupuncture for the Treatment of Peripheral Neuropathy: A Systematic Review and Meta-Analysis.
Authors:Dimitrova A, Murchison C, Oken B
Institution:Department of Neurology, Oregon Health and Science University , Portland, OR.
Journal:J Altern Complement Med. 2017 Mar;23(3):164-179. doi: 10.1089/acm.2016.0155. Epub 2017 Jan 23.

9:Clinical effectiveness of low-level laser treatment on peripheral somatosensory neuropathy.
Authors:Fallah A, Mirzaei A, Gutknecht N, Demneh AS
Institution:AALZ, Aachen, Germany.
Journal:Lasers Med Sci. 2017 Apr;32(3):721-728. doi: 10.1007/s10103-016-2137-y. Epub 2017 Jan 10.

10:Perceived Physical Activity Decline as a Mediator in the Relationship Between Pain Catastrophizing, Disability, and Quality of Life in Patients with Painful Diabetic Neuropathy.
Authors:Geelen CC, Kindermans HP, van den Bergh JP, Verbunt JA
Institution:Adelante Centre of Expertise in Rehabilitation and Audiology, Hoensbroek, The Netherlands. University, Maastricht, The Netherlands. University, Maastricht, The Netherlands. Maastricht, The Netherlands. Netherlands. University, Maastricht, The Netherlands.
Journal:Pain Pract. 2017 Mar;17(3):320-328. doi: 10.1111/papr.12449. Epub 2016 Mar 23.

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