Bladder Cancer
January 2017 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Bladder Cancer abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Bladder Cancer. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Bladder Cancer. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Bladder Cancer every 3 months. Thank you for your ongoing subscription to this publication.

Sincerely,
Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:New Agents for the Treatment of Advanced Bladder Cancer.
Authors:Cheetham PJ, Petrylak DP
Journal:Oncology (Williston Park). 2016 Jun;30(6):571-9, 588.

2:Natural biology and management of nonmuscle invasive bladder cancer.
Authors:Scarpato KR, Tyson MD, Clark PE
Institution:Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Journal:Curr Opin Oncol. 2016 May;28(3):210-5. doi: 10.1097/CCO.0000000000000278.

3:Experience with Sequential Intravesical Gemcitabine and Docetaxel as Salvage Therapy for Non-Muscle Invasive Bladder Cancer.
Authors:Velaer KN, Steinberg RL, Thomas LJ, O'Donnell MA, Nepple KG
Institution:Department of Urology, University of Iowa, 200 Hawkins Dr., 3 RCP, Iowa City, IA, 52242-1089, USA. 52242-1089, USA. 52242-1089, USA. 52242-1089, USA. 52242-1089, USA. kenneth-nepple@uiowa.edu.
Journal:Curr Urol Rep. 2016 May;17(5):38. doi: 10.1007/s11934-016-0594-2.

4:Cigarette smoking and bladder cancer risk: an evaluation based on a systematic review of epidemiologic evidence in the Japanese population.
Authors:Masaoka H, Matsuo K, Ito H, Wakai K, Nagata C, Nakayama T, Sadakane A, Tanaka K, Tamakoshi A, Sugawara Y, Mizoue T, Sawada N, Inoue M, Tsugane S, Sasazuki S
Institution:Division of Molecular Medicine, Aichi Cancer Center Research Institute, Nagoya Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka.; Division of Molecular Medicine, Aichi Cancer Center Research Institute, Nagoya Department of Epidemiology, Nagoya University Graduate School of Medicine, Nagoya kmatsuo@aichi-cc.jp.; Department of Epidemiology, Nagoya University Graduate School of Medicine, Nagoya Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya.; Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya.; Department of Epidemiology and Preventive Medicine, Gifu University Graduate School of Medicine, Gifu.
Journal:Jpn J Clin Oncol. 2016 Mar;46(3):273-83. doi: 10.1093/jjco/hyv188. Epub 2016 Jan 17.

5:A Review Comparing Experience and Results with Bipolar Versus Monopolar Resection for Treatment of Bladder Tumors.
Authors:Osman Y, Harraz AM
Institution:Urology and Nephrology Center, Mansoura University, 70th Gomhoria St., 35516, Mansoura, Egypt. y_osman99@yahoo.com. Mansoura, Egypt.
Journal:Curr Urol Rep. 2016 Mar;17(3):21. doi: 10.1007/s11934-016-0579-1.

6:Comparing the Efficiency and Safety of Bipolar and Monopolar Transurethral Resection for Non-Muscle Invasive Bladder Tumors: A Systematic Review and Meta-Analysis.
Authors:Cui Y, Chen H, Liu L, Chen J, Qi L, Zu X
Institution:Department of Urology, Xiangya Hospital, Central South University , Changsha, Hunan, China . Hunan, China . Hunan, China . Hunan, China . Hunan, China . Hunan, China .
Journal:J Laparoendosc Adv Surg Tech A. 2016 Mar;26(3):196-202. doi: 10.1089/lap.2015.0507. Epub 2016 Jan 22.

7:Effectiveness of Adjuvant Chemotherapy for Locally Advanced Bladder Cancer.
Authors:Galsky MD, Stensland KD, Moshier E, Sfakianos JP, McBride RB, Tsao CK, Casey M, Boffetta P, Oh WK, Mazumdar M, Wisnivesky JP
Institution:Matthew D. Galsky, Erin Moshier, Che-Kai Tsao, Martin Casey, Paolo Boffetta, and William K. Oh, Tisch Cancer Institute at Mount Sinai; Erin Moshier, John P. Sfakianos, Russell B. McBride, Paolo Boffetta, Madhu Mazumdar, and Juan P. Wisnivesky, Icahn School of Medicine at Mount Sinai, New York, NY; and Kristian D. Stensland, Lahey Clinic, Burlington, MA. matthew.galsky@mssm.edu.
Journal:J Clin Oncol. 2016 Mar 10;34(8):825-32. doi: 10.1200/JCO.2015.64.1076. Epub 2016 Jan 19.

8:Chemotherapy for Muscle-Invasive Bladder Cancer: Better Late Than Never?
Authors:Sonpavde G, Gordetsky JB, Lockhart ME, Nix JW
Institution:University of Alabama, Birmingham, School of Medicine and Veterans Affairs Medical Center, Birmingham, AL gsonpavde@uabmc.edu.
Journal:J Clin Oncol. 2016 Mar 10;34(8):780-5. doi: 10.1200/JCO.2015.65.4442. Epub 2016 Jan 19.

9:"En Bloc" Resection of Nonmuscle Invasive Bladder Cancer: A Prospective Single-center Study.
Authors:Hurle R, Lazzeri M, Colombo P, Buffi N, Morenghi E, Peschechera R, Castaldo L, Pasini L, Casale P, Seveso M, Zandegiacomo S, Taverna G, Benetti A, Lughezzani G, Fiorini G, Guazzoni G
Institution:Department of Urology, Istituto Clinico Humanitas IRCCS, Clinical and Research Hospital, Rozzano (Milan), Italy. Electronic address: massimo.lazzeri@humanitas.it.; Department of Pathology, Istituto Clinico Humanitas IRCCS, Clinical and Research Hospital, Rozzano (Milan), Italy.; Biostatistic Unit, Istituto Clinico Humanitas IRCCS, Clinical and Research Hospital, Rozzano (Milan), Italy.; Department of Urology, Istituto Clinico Humanitas IRCCS, Clinical and Research Hospital, Rozzano (Milan), Italy; Department of Pathology, Istituto Clinico Humanitas IRCCS, Clinical and Research Hospital, Rozzano (Milan), Italy; Biostatistic Unit, Istituto Clinico Humanitas IRCCS, Clinical and Research Hospital, Rozzano (Milan), Italy; Department of Urology, Humanitas Clinical and Research Center, Humanitas University, Rozzano (Milan), Italy.
Journal:Urology. 2016 Apr;90:126-30. doi: 10.1016/j.urology.2016.01.004. Epub 2016 Jan 14.

10:Treatment of muscle-invasive bladder cancer: A systematic review.
Authors:Chou R, Selph SS, Buckley DI, Gustafson KS, Griffin JC, Grusing SE, Gore JL
Institution:Department of Medical Informatics and Clinical Epidemiology, Pacific Northwest Evidence-based Practice Center, Oregon Health & Science University, Portland, Oregon.; Department of Urology, Pacific Northwest Evidence-based Practice Center, University of Washington CHASE Alliance, Seattle, Washington.
Journal:Cancer. 2016 Mar 15;122(6):842-51. doi: 10.1002/cncr.29843. Epub 2016 Jan 15.

11:The treatment of muscle-invasive bladder cancer in geriatric patients.
Authors:Grubmueller B, Seitz C, Shariat SF
Institution:aDepartment of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna General Hospital, Vienna, Austria bWeill Medical College of Cornell University, New York City, New York cUT Southwestern, Dallas, Texas, USA.
Journal:Curr Opin Urol. 2016 Mar;26(2):160-4. doi: 10.1097/MOU.0000000000000262.

12:Stapled orthotopic ileal neobladder after radical cystectomy for bladder cancer: Functional results and complications over a 20-year period.
Authors:Muto G, Collura D, Simone G, Muto GL, Rosso R, Giacobbe A, Castelli E
Institution:Department of Urology, San Giovanni Bosco Hospital, Turin, Italy. address: castelli2006@hotmail.it.
Journal:Eur J Surg Oncol. 2016 Mar;42(3):412-8. doi: 10.1016/j.ejso.2015.11.010. Epub 2015 Dec 2.

13:Systematic review and meta-analysis of non RCT's on health related quality of life after radical cystectomy using validated questionnaires: Better results with orthotopic neobladder versus ileal conduit.
Authors:Cerruto MA, D'Elia C, Siracusano S, Gedeshi X, Mariotto A, Iafrate M, Niero M, Lonardi C, Bassi P, Belgrano E, Imbimbo C, Racioppi M, Talamini R, Ciciliato S, Toffoli L, Rizzo M, Visalli F, Verze P, Artibani W
Institution:University of Verona, Urology Department, Verona, Italy. Electronic address: mariaangela.cerruto@univr.it.; University of Verona, Urology Department, Verona, Italy. Electronic address: karolinedelia@gmail.com.; Trieste University, Urology Department, Trieste, Italy. Electronic address: siracus@units.it.; University of Verona, Urology Department, Verona, Italy. Electronic address: xhoagedeschi@gmail.com.; University of Verona, Urology Department, Verona, Italy. Electronic address: arianna.mariotto@gmail.com.
Journal:Eur J Surg Oncol. 2016 Mar;42(3):343-60. doi: 10.1016/j.ejso.2015.10.001. Epub 2015 Nov 9.

14:Urine cytology in monitoring recurrence in urothelial carcinoma after radical cystectomy and urinary diversion.
Authors:Chen H, Liu L, Pambuccian SE, Barkan GA, Quek ML, Wojcik EM
Institution:Department of Pathology, Loyola University Medical Center, Maywood, Illinois.
Journal:Cancer Cytopathol. 2016 Apr;124(4):273-8. doi: 10.1002/cncy.21650. Epub 2015 Nov 13.

15:Urethral recurrence after cystectomy: current preventative measures, diagnosis and management.
Authors:Chan Y, Fisher P, Tilki D, Evans CP
Institution:Department of Urology, Medical Center, University of California, Davis, Sacramento, CA, USA. Sacramento, CA, USA. Sacramento, CA, USA. Sacramento, CA, USA.
Journal:BJU Int. 2016 Apr;117(4):563-9. doi: 10.1111/bju.13370. Epub 2015 Dec 12.

16:Repeat transurethral resection for non-muscle-invasive bladder cancer: a contemporary series.
Authors:Gendy R, Delprado W, Brenner P, Brooks A, Coombes G, Cozzi P, Nash P, Patel MI
Institution:Department of Urology, St George Hospital, Sydney, NSW, Australia. Sydney, Sydney, NSW, Australia. Sydney, Sydney, NSW, Australia.
Journal:BJU Int. 2016 Apr;117 Suppl 4:54-9. doi: 10.1111/bju.13265. Epub 2015 Oct 21.

17:Finasteride Reduces Risk of Bladder Cancer in a Large Prospective Screening Study.
Authors:Morales EE, Grill S, Svatek RS, Kaushik D, Thompson IM Jr, Ankerst DP, Liss MA
Institution:Department of Urology, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA. Electronic address: Liss@uthscsa.edu.; Life Sciences Mathematics Unit, Technische Universitaet Muenchen, Munich, Germany.
Journal:Eur Urol. 2016 Mar;69(3):407-10. doi: 10.1016/j.eururo.2015.08.029. Epub 2015 Aug 28.

18:Comparing long-term outcomes of primary and progressive carcinoma invading bladder muscle after radical cystectomy.
Authors:Moschini M, Sharma V, Dell'oglio P, Cucchiara V, Gandaglia G, Cantiello F, Zattoni F, Pellucchi F, Briganti A, Damiano R, Montorsi F, Salonia A, Colombo R
Institution:Department of Urology, Urological Research Institute, San Raffaele Scientific Institute, Vita-Salute University, Milan, Italy.; Doctorate Research Program, Magna Graecia University of Catanzaro, Catanzaro, Italy.; Department of Urology, Mayo Clinic Rochester, Rochester, MN, USA.; Department of Urology, University of Padua, Padua, Italy.; Department of Urology, Papa Giovanni XXIII Hospital, Bergamo, Italy.
Journal:BJU Int. 2016 Apr;117(4):604-10. doi: 10.1111/bju.13146. Epub 2015 Jun 3.

19:Intravesical gemcitabine in combination with mitomycin C as salvage treatment in recurrent non-muscle-invasive bladder cancer.
Authors:Cockerill PA, Knoedler JJ, Frank I, Tarrell R, Karnes RJ
Institution:Department of Urology, Mayo Clinic, Rochester, MN, USA.
Journal:BJU Int. 2016 Mar;117(3):456-62. doi: 10.1111/bju.13088. Epub 2015 May 23.

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