Ductal Carcinoma in Situ of the Breast
July 2019 Issue

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Ductal Carcinoma in Situ of the Breast abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Ductal Carcinoma in Situ of the Breast. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Ductal Carcinoma in Situ of the Breast. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Ductal Carcinoma in Situ of the Breast every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.

1:The Latissimus Dorsi Myocutaneous Flap Is a Safe and Effective Method of Partial Breast Reconstruction in the Setting of Breast-Conserving Therapy.
Authors:Mericli AF, Szpalski C, Schaverien MV, Selber JC, Adelman DM, Garvey PB, Villa MT, Robb G, Baumann DP
Institution:Houston, Texas From the Department of Plastic Surgery, University of Texas M. D. Anderson Cancer Center.
Journal:Plast Reconstr Surg. 2019 May;143(5):927e-935e. doi: 10.1097/PRS.0000000000005577.

2:Evaluating the relationship between ductal carcinoma in situ, calcifications, and margin status in patients undergoing breast conserving surgery.
Authors:Bruenderman EH, Bhutiani N, Mercer MK, McMasters KM, Sanders MAG, Ajkay NL
Institution:Division of Surgical Oncology, Department of Surgery, University of Louisville, Louisville, Kentucky.
Journal:J Surg Oncol. 2019 May;119(6):694-699. doi: 10.1002/jso.25388. Epub 2019 Feb 11.

3:Influence of ductal carcinoma in situ on the outcome of invasive breast cancer. A prospective cohort study.
Authors:Lopez Gordo S, Blanch Falp J, Lopez-Gordo E, Just Roig E, Encinas Mendez J, Seco Calvo J
Institution:Mammary Pathology Unit of "Consorci Sanitari del Garraf" and the "Consorci Sanitari de l'Alt Penedes", Ronda Sant Camil s/n, 00810, San Pere de Ribes, Barcelona, Spain. Electronic address: slopezg@csg.cat. Sanitari de l'Alt Penedes", Ronda Sant Camil s/n, 00810, San Pere de Ribes, Barcelona, Spain. Electronic address: jblanch@csg.cat. Avenue, 10029, New York city, USA. Electronic address: estrella.lopezgordo@mssm.edu. Sanitari de l'Alt Penedes", Ronda Sant Camil s/n, 00810, San Pere de Ribes, Barcelona, Spain. Electronic address: ejust@csg.cat. Sanitari de l'Alt Penedes", Ronda Sant Camil s/n, 00810, San Pere de Ribes, Barcelona, Spain. Electronic address: xencinas@gmail.com. Researcher of Basque Country University, Campus de Vegazana, 24071, Leon, Spain. Electronic address: jesus.seco@unileon.es.
Journal:Int J Surg. 2019 Mar;63:98-106. doi: 10.1016/j.ijsu.2019.01.016. Epub 2019 Feb 6.

4:Predicting underestimation of ductal carcinoma in situ: a comparison between radiomics and conventional approaches.
Authors:Li J, Song Y, Xu S, Wang J, Huang H, Ma W, Jiang X, Wu Y, Cai H, Li L
Institution:Department of Medical Imaging, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangzhou, People's Republic of China. li2@mail.sysu.edu.cn.; School of Computer Science and Engineering, South China University of Technology, Guangzhou, Guangdong, People's Republic of China.; Department of Medical Imaging Center, Shenzhen Hospital of Southern Medical University, Shenzhen, Guangdong, People's Republic of China.
Journal:Int J Comput Assist Radiol Surg. 2019 Apr;14(4):709-721. doi: 10.1007/s11548-018-1900-x. Epub 2018 Dec 19.

5:Microinvasive breast carcinoma: An analysis from ten Senonetwork Italia breast centres.
Authors:Costarelli L, Cianchetti E, Corsi F, Friedman D, Ghilli M, Lacaria M, Menghini L, Murgo R, Ponti A, Rinaldi S, Del Turco MR, Taffurelli M, Tinterri C, Tomatis M, Fortunato L
Institution:Breast Unit, San Giovanni-Addolorata Hospital, Rome, Italy. Electronic address: lcostarelli@hsangiovanni.roma.it.; Breast Centre Asl02 Abruzzo, P.O. G. Bernabeo, Ortona, Italy. Electronic address: cianchet@unich.it.; Surgery Department, Breast Unit, ICS Maugeri S.p.A, Pavia, Italy; Department of Biomedical and Clinical Sciences 'L. Sacco', University of Milan, Milan, Italy. Electronic address: fabio.corsi@unimi.it.; UO Chirurgia Senologica, Ospedale Policlinico San Martino, Genova, Italy. Electronic address: friedman@unige.it.; Breast Cancer Center, University Hospital of Pisa, Italy. Electronic address: matteo.ghilli@gmail.com.
Journal:Eur J Surg Oncol. 2019 Feb;45(2):147-152. doi: 10.1016/j.ejso.2018.09.024. Epub 2018 Oct 16.

6:Adjuvant radiation therapy in small ductal carcinoma in situ.
Authors:Cho WK, Choi DH, Kim H, Noh JM, Park W, Cha H
Institution:Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address: doho.choi@samsung.com.
Journal:Breast. 2019 Feb;43:55-58. doi: 10.1016/j.breast.2018.11.004. Epub 2018 Nov 9.

7:Regional Market Competition and the Use of Immediate Breast Reconstruction After Mastectomy.
Authors:Wright JD, Chen L, Accordino M, Taback B, Ananth CV, Neugut AI, Hershman DL
Institution:Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons, 161 Fort Washington Avenue, 4th Floor, New York, USA. jw2459@columbia.edu.; Herbert Irving Comprehensive Cancer Center, Columbia University College of Physicians and Surgeons, New York, USA. jw2459@columbia.edu.; New York Presbyterian Hospital, New York, USA. jw2459@columbia.edu.; Mailman School of Public Health, Columbia University, New York, USA.
Journal:Ann Surg Oncol. 2019 Jan;26(1):62-70. doi: 10.1245/s10434-018-6825-7. Epub 2018 Oct 16.

8:Comparison of Clinical and Pathologic Characteristics of Ductal Carcinoma in Situ Detected on Mammography versus Ultrasound Only in Asymptomatic Patients.
Authors:Moon HJ, Kim EK, Kim MJ, Yoon JH, Park VY
Institution:Department of Radiology, Research Institute of Radiologic Science, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. Electronic address: artemis4u@yuhs.ac.
Journal:Ultrasound Med Biol. 2019 Jan;45(1):68-77. doi: 10.1016/j.ultrasmedbio.2018.09.003. Epub 2018 Oct 12.

9:Progression of ductal carcinoma in situ to invasive breast cancer: comparative genomic sequencing.
Authors:Doebar SC, Krol NM, van Marion R, Brouwer RWW, van Ijcken WFJ, Martens JM, Dinjens WNM, van Deurzen CHM
Institution:Department of Pathology, Erasmus MC Cancer Institute, Rotterdam, Netherlands. s.doebar@erasmusmc.nl. s.doebar@erasmusmc.nl. Institute, Rotterdam, Netherlands.
Journal:Virchows Arch. 2019 Feb;474(2):247-251. doi: 10.1007/s00428-018-2463-5. Epub 2018 Oct 4.

10:Predictors of Invasive Breast Cancer in Patients With Ductal Carcinoma In Situ in Ultrasound-Guided Core Needle Biopsy.
Authors:Shin YJ, Kim SM, Yun B, Jang M, Kim B, Lee SH
Institution:Department of Radiology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam-si, Korea.
Journal:J Ultrasound Med. 2019 Feb;38(2):481-488. doi: 10.1002/jum.14722. Epub 2018 Aug 1.

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