Ductal Carcinoma in Situ of the Breast
January 2017 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Ductal Carcinoma in Situ of the Breast abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Ductal Carcinoma in Situ of the Breast. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Ductal Carcinoma in Situ of the Breast. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Ductal Carcinoma in Situ of the Breast every 3 months. Thank you for your ongoing subscription to this publication.

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Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Trends in Health-Related Quality of Life After a Diagnosis of Ductal Carcinoma In Situ.
Authors:Hart V, Sprague BL, Lakoski SG, Hampton JM, Newcomb PA, Gangnon RE, Trentham-Dietz A
Institution:Vicki Hart, Brian L. Sprague, and Susan G. Lakoski, University of Vermont; Brian L. Sprague and Susan G. Lakoski, University of Vermont Cancer Center, Burlington, VT; John M. Hampton, Ronald E. Gangnon, and Amy Trentham-Dietz, University of Wisconsin, Madison, WI; and Polly A. Newcomb, Fred Hutchinson Cancer Research Center, Seattle, WA. victoria.hart@uvm.edu.
Journal:J Clin Oncol. 2016 Apr 20;34(12):1323-9. doi: 10.1200/JCO.2015.62.7281. Epub 2016 Feb 16.

2:Genetic predisposition to ductal carcinoma in situ of the breast.
Authors:Petridis C, Brook MN, Shah V, Kohut K, Gorman P, Caneppele M, Levi D, Papouli E, Orr N, Cox A, Cross SS, Dos-Santos-Silva I, Peto J, Swerdlow A, Schoemaker MJ, Bolla MK, Wang Q, Dennis J, Michailidou K, Benitez J, Gonzalez-Neira A, Tessier DC, Vincent D, Li J, Figueroa J, Kristensen V, Borresen-Dale AL, Soucy P, Simard J, Milne RL, Giles GG, Margolin S, Lindblom A, Bruning T, Brauch H, Southey MC, Hopper JL, Dork T, Bogdanova NV, Kabisch M, Hamann U, Schmutzler RK, Meindl A, Brenner H, Arndt V, Winqvist R, Pylkas K, Fasching PA, Beckmann MW, Lubinski J, Jakubowska A, Mulligan AM, Andrulis IL, Tollenaar RA, Devilee P, Le Marchand L, Haiman CA, Mannermaa A, Kosma VM, Radice P, Peterlongo P, Marme F, Burwinkel B, van Deurzen CH, Hollestelle A, Miller N, Kerin MJ, Lambrechts D, Floris G, Wesseling J, Flyger H, Bojesen SE, Yao S, Ambrosone CB, Chenevix-Trench G, Truong T, Guenel P, Rudolph A, Chang-Claude J, Nevanlinna H, Blomqvist C, Czene K, Brand JS, Olson JE, Couch FJ, Dunning AM, Hall P, Easton DF, Pharoah PD, Pinder SE, Schmidt MK, Tomlinson I, Roylance R, Garcia-Closas M, Sawyer EJ
Institution:Research Oncology, Guy's Hospital, King's College London, London, UK. christos.petridis@kcl.ac.uk.; Medical and Molecular Genetics, Guy's Hospital, King's College London, London, UK. christos.petridis@kcl.ac.uk.; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK. Mark.Brook@icr.ac.uk.; Research Oncology, Guy's Hospital, King's College London, London, UK. vandna.shah@kcl.ac.uk.; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK. kohut.kelly@gmail.com.
Journal:Breast Cancer Res. 2016 Feb 17;18(1):22. doi: 10.1186/s13058-016-0675-7.

3:Characteristics of second breast events among women treated with breast-conserving surgery for DCIS in the community.
Authors:Hassett MJ, Jiang W, Habel LA, Nekhlyudov L, Achacoso N, Acton L, Schnitt SJ, Schrag D, Punglia RS
Institution:Division of Population Sciences, Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA, 02215-5450, USA. michael_hassett@dfci.harvard.edu. wjiang3@partners.org. larissa_nekhlyudov@harvardpilgrim.org. larissa_nekhlyudov@harvardpilgrim.org. ninah.s.achacoso@nsmtp.kp.org. sschnitt@caregroup.harvard.edu. Cancer Institute, 450 Brookline Avenue, Boston, MA, 02215-5450, USA. deb_schrag@dfci.harvard.edu. rpunglia@lroc.harvard.edu.
Journal:Breast Cancer Res Treat. 2016 Feb;155(3):541-9. doi: 10.1007/s10549-016-3692-4. Epub 2016 Feb 3.

4:Ductal carcinoma in situ of the breast: the importance of morphologic and molecular interactions.
Authors:Mardekian SK, Bombonati A, Palazzo JP
Institution:Department of Pathology, Thomas Jefferson University, Philadelphia, PA 19107. Electronic address: Stacey.Mardekian@jefferson.edu. Electronic address: BombonaA@einstein.edu. Electronic address: Juan.Palazzo@jefferson.edu.
Journal:Hum Pathol. 2016 Mar;49:114-23. doi: 10.1016/j.humpath.2015.11.003. Epub 2015 Nov 17.

5:Tamoxifen Initiation After Ductal Carcinoma In Situ.
Authors:Nichols HB, Bowles EJ, Islam J, Madziwa L, Sturmer T, Tran DT, Buist DS
Institution:Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, Chapel Hill, North Carolina, USA hazel.nichols@unc.edu. of North Carolina, Chapel Hill, Chapel Hill, North Carolina, USA. of North Carolina, Chapel Hill, Chapel Hill, North Carolina, USA.
Journal:Oncologist. 2016 Feb;21(2):134-40. doi: 10.1634/theoncologist.2015-0310. Epub 2016 Jan 14.

6:Ductal carcinoma in situ - update on risk assessment and management.
Authors:Pang JM, Gorringe KL, Fox SB
Institution:Department of Pathology, Peter MacCallum Cancer Centre, East Melbourne, Vic., Australia. Vic., Australia. Australia. Australia. Vic., Australia.
Journal:Histopathology. 2016 Jan;68(1):96-109. doi: 10.1111/his.12796.

7:Updates in the treatment of ductal carcinoma in situ of the breast.
Authors:Lebeau A, Kuhn T
Institution:aInstitut fur Pathologie, Universitatsklinikum Hamburg-Eppendorf, Hamburg bGemeinschaftspraxis fur Pathologie, Lubeck cKlinik fur Frauenheilkunde und Geburtshilfe, Klinikum Esslingen, Esslingen, Germany.
Journal:Curr Opin Obstet Gynecol. 2016 Feb;28(1):49-58. doi: 10.1097/GCO.0000000000000237.

8:Ductal carcinoma in situ (DCIS) treated by mastectomy, or local excision with or without radiotherapy: A monocentric, retrospective study of 608 women.
Authors:Frank S, Dupont A, Teixeira L, Porcher R, De Roquancourt A, Giacchetti S, Espie M, Cuvier C
Institution:Breast Disease Centre, Hopital Saint Louis, 1 Avenue Claude Vellefaux, 75010 Paris, France. Electronic address: sophie.frank01@gmail.com.; Clinical Epidemiology, Hotel Dieu, 1 Parvis Notre-Dame - Place Jean-Paul II, 75004 Paris, France.; Breast Disease Centre, Hopital Saint Louis, 1 Avenue Claude Vellefaux, 75010 Paris, France; University Paris Diderot, 5 rue Thomas-Mann, 75013 Paris, France.
Journal:Breast. 2016 Feb;25:51-6. doi: 10.1016/j.breast.2015.10.008. Epub 2015 Nov 10.

9:Targeted Intraoperative Radiotherapy for the Management of Ductal Carcinoma In Situ of the Breast.
Authors:Rivera R, Banks A, Casillas-Lopez A, Rashtian A, Lewinsky B, Sheth P, Hovannesian-Larsen L, Brousseau D, Iyengar G, Holmes DR
Institution:University of California, Los Angeles - David Geffen School of Medicine, Los Angeles, California. Angeles, California. Angeles, California. Angeles, California. Angeles, California. Angeles, California. Angeles, California. Angeles, California.
Journal:Breast J. 2016 Jan-Feb;22(1):63-74. doi: 10.1111/tbj.12516. Epub 2015 Nov 3.

10:Microcalcifications in 1657 Patients with Pure Ductal Carcinoma in Situ of the Breast: Correlation with Clinical, Histopathologic, Biologic Features, and Local Recurrence.
Authors:Rauch GM, Hobbs BP, Kuerer HM, Scoggins ME, Benveniste AP, Park YM, Caudle AS, Fox PS, Smith BD, Adrada BE, Krishnamurthy S, Yang WT
Institution:Department of Diagnostic Radiology, Unit 1473, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. gmrauch@mdanderson.org. Cancer Center, Houston, TX, USA. Cancer Center, Houston, TX, USA. Anderson Cancer Center, Houston, TX, USA. Cancer Center, Houston, TX, USA. Cancer Center, Houston, TX, USA. Cancer Center, Houston, TX, USA. Cancer Center, Houston, TX, USA. Cancer Center, Houston, TX, USA. Anderson Cancer Center, Houston, TX, USA. Anderson Cancer Center, Houston, TX, USA. Anderson Cancer Center, Houston, TX, USA.
Journal:Ann Surg Oncol. 2016 Feb;23(2):482-9. doi: 10.1245/s10434-015-4876-6. Epub 2015 Sep 28.

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