Ductal Carcinoma in Situ of the Breast
October 2017 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Ductal Carcinoma in Situ of the Breast abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Ductal Carcinoma in Situ of the Breast. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Ductal Carcinoma in Situ of the Breast. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Ductal Carcinoma in Situ of the Breast every 3 months. Thank you for your ongoing subscription to this publication.

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Elliot Jacob, Ph.D.
Vice-President - Content
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1:Detection of Ductal Carcinoma In Situ by Ultrasound and Mammography: Size-dependent Inaccuracy.
Authors:Eichler C, Abrar S, Puppe J, Arndt M, Ohlinger R, Hahn M, Warm M
Institution:Breast Center, Municipal Hospital Holweide, Cologne, Germany ceichler@gmail.com eichlerc@kliniken-koeln.de. Germany. Germany. Germany.
Journal:Anticancer Res. 2017 Sep;37(9):5065-5070.

2:Risk of death from breast cancer after treatment for ductal carcinoma in situ.
Authors:Wadsten C, Garmo H, Fredriksson I, Sund M, Warnberg F
Institution:Department of Surgery, Sundsvall Hospital, Sundsvall, Sweden. Sweden. Population Health, King's College, London, UK. Sweden. Stockholm, Sweden.
Journal:Br J Surg. 2017 Oct;104(11):1506-1513. doi: 10.1002/bjs.10589. Epub 2017 Aug 22.

3:Oncologic Safety of Nipple-Sparing Mastectomy in Women with Breast Cancer.
Authors:Smith BL, Tang R, Rai U, Plichta JK, Colwell AS, Gadd MA, Specht MC, Austen WG Jr, Coopey SB
Institution:Division of Surgical Oncology, Massachusetts General Hospital, Boston, MA. Electronic address: blsmith1@mgh.harvard.edu. Boston, MA. Boston, MA.
Journal:J Am Coll Surg. 2017 Sep;225(3):361-365. doi: 10.1016/j.jamcollsurg.2017.06.013. Epub 2017 Jul 17.

4:NRG Oncology-Radiation Therapy Oncology Group Study 1014: 1-Year Toxicity Report From a Phase 2 Study of Repeat Breast-Preserving Surgery and 3-Dimensional Conformal Partial-Breast Reirradiation for In-Breast Recurrence.
Authors:Arthur DW, Winter KA, Kuerer HM, Haffty BG, Cuttino LW, Todor DA, Simone NL, Hayes SB, Woodward WA, McCormick B, Cohen RJ, Sahijdak WM, Canaday DJ, Brown DR, Currey AD, Fisher CM, Jagsi R, White J
Institution:Department of Radiation Oncology, Virginia Commonwealth University, Richmond, Virginia. Electronic address: douglas.arthur@vcuhealth.org. Cancer Center, Houston, Texas. Brunswick, New Jersey. Virginia. Virginia. Philadelphia, Pennsylvania. Pennsylvania. of Texas MD Anderson Cancer Center, Houston, Texas. York, New York. Baltimore, Maryland. Clinical Oncology Program, Ann Arbor, Michigan. North Carolina. Wisconsin. Colorado. Arbor, Michigan.
Journal:Int J Radiat Oncol Biol Phys. 2017 Aug 1;98(5):1028-1035. doi: 10.1016/j.ijrobp.2017.03.016. Epub 2017 Mar 18.

5:Maximizing the Clinical Benefit of Anthracyclines in Addition to Taxanes in the Adjuvant Treatment of Early Breast Cancer.
Authors:Curigliano G, Criscitiello C
Institution:Giuseppe Curigliano and Carmen Criscitiello, Istituto Europeo di Oncologia, Milano, Italy. Milano, Italy.
Journal:J Clin Oncol. 2017 Aug 10;35(23):2600-2603. doi: 10.1200/JCO.2017.72.5960. Epub 2017 Jun 29.

6:The diagnostic challenge of low-grade ductal carcinoma in situ.
Authors:Onega T, Weaver DL, Frederick PD, Allison KH, Tosteson ANA, Carney PA, Geller BM, Longton GM, Nelson HD, Oster NV, Pepe MS, Elmore JG
Institution:Department of Biomedical Data Science, Department of Epidemiology, The Dartmouth Institute for Health Policy and Clinical Practice and Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA. Electronic address: Tracy.L.Onega@dartmouth.edu. VT, USA. USA. USA. Practice and Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA. OR, USA. of Medical Informatics and Clinical Epidemiology and Department of Medicine, Oregon Health & Science University, Portland, OR, USA. USA. USA.
Journal:Eur J Cancer. 2017 Jul;80:39-47. doi: 10.1016/j.ejca.2017.04.013. Epub 2017 May 20.

7:Quality of Patient Decisions About Breast Reconstruction After Mastectomy.
Authors:Lee CN, Deal AM, Huh R, Ubel PA, Liu YJ, Blizard L, Hunt C, Pignone MP
Institution:Department of Plastic Surgery, College of Medicine, The Ohio State University, Columbus. Cancer Hospital, The Ohio State University, Columbus. Ohio State University, Columbus. North Carolina-Chapel Hill. North Carolina-Chapel Hill. University, Durham, North Carolina. University, Durham, North Carolina. Durham, North Carolina. North Carolina-Chapel Hill. University of North Carolina-Chapel Hill. Austin.
Journal:JAMA Surg. 2017 Aug 1;152(8):741-748. doi: 10.1001/jamasurg.2017.0977.

8:Impact of Preoperative Breast MR Imaging and MR-guided Surgery on Diagnosis and Surgical Outcome of Women with Invasive Breast Cancer with and without DCIS Component.
Authors:Kuhl CK, Strobel K, Bieling H, Wardelmann E, Kuhn W, Maass N, Schrading S
Institution:From the Department of Diagnostic and Interventional Radiology (C.K.K., K.S., S.S.), Section of Bioinformatics, Department of Diagnostic and Interventional Radiology (H.B.), and Department of Gynecology and Gynecologic Oncology (N.M.), University of Aachen, RWTH, Pauwelsstr 30, 52074 Aachen, Germany; Department of Pathology, University of Muenster, Muenster, Germany (E.W.); and Department of Gynecology, University of Bonn, Bonn, Germany (W.K.).
Journal:Radiology. 2017 Sep;284(3):645-655. doi: 10.1148/radiol.2017161449. Epub 2017 Apr 26.

9:Tumor thickness and histological features as predictors of invasive foci within preoperatively diagnosed ductal carcinoma in situ.
Authors:Mori K, Takeda M, Kodama Y, Kiyokawa H, Yasojima H, Mizutani M, Otani Y, Morikawa N, Masuda N, Mano M
Institution:Department of Pathology, National Hospital Organization, Osaka National Hospital, Osaka, 5400006, Japan. Electronic address: kiyoshim@onh.go.jp.; Department of Pathology, Yao Municipal Hospital, Yao, 5810069, Japan. Electronic address: m-takeda@city.yao.osaka.jp.; Department of Pathology and Applied Neurobiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, 6028566, Japan. Electronic address: kodamayo@koto.kpu-m.ac.jp.; Department of Pathology, National Hospital Organization, Osaka National Hospital, Osaka, 5400006, Japan. Electronic address: hkiyo@onh.go.jp.; Department of Surgery, Breast Surgery, National Hospital Organization, Osaka National Hospital, Osaka, 5400006, Japan. Electronic address: h_yasojima@yahoo.co.jp.
Journal:Hum Pathol. 2017 Jun;64:145-155. doi: 10.1016/j.humpath.2017.04.004. Epub 2017 Apr 20.

10:Identifying a subset of patients with DCIS who have a low likelihood of residual disease at surgical excision following a core needle biopsy.
Authors:Murphy BL, Gonzalez AB, Conners AL, Henrichsen TL, Keeney MG, Chen B, Nguyen TT, Harmsen WS, Habermann EB, Shah HN, Jakub JW
Institution:Department of Surgery, Mayo Clinic, Rochester, Minnesota. Delivery, Mayo Clinic, Rochester, Minnesota. Delivery, Mayo Clinic, Rochester, Minnesota.
Journal:J Surg Oncol. 2017 Aug;116(2):213-219. doi: 10.1002/jso.24649. Epub 2017 Apr 18.

11:Association of Radiotherapy Boost for Ductal Carcinoma In Situ With Local Control After Whole-Breast Radiotherapy.
Authors:Moran MS, Zhao Y, Ma S, Kirova Y, Fourquet A, Chen P, Hoffman K, Hunt K, Wong J, Halasz LM, Freedman G, Prosnitz R Jr, Yassa M, Nguyen DHA, Hijal T, Haffty BG, Wai ES, Truong PT
Institution:Smilow Cancer Center, Department of Therapeutic Radiology, Yale School of Medicine, New Haven, Connecticut. Connecticut. Connecticut. Medicine, Royal Oak, Michigan. Houston. Houston. Institute, Boston, Massachusetts. Institute, Boston, Massachusetts. Maisonneuve-Rosemont, Montreal, Quebec, Canada. Maisonneuve-Rosemont, Montreal, Quebec, Canada. Quebec, Canada. Brunswick, New Jersey. British Columbia, Canada. British Columbia, Canada.
Journal:JAMA Oncol. 2017 Aug 1;3(8):1060-1068. doi: 10.1001/jamaoncol.2016.6948.

12:Surgical excision without whole breast irradiation for complete resection of ductal carcinoma in situ identified using strict, unified criteria.
Authors:Sakai T, Iwase T, Teruya N, Kataoka A, Kitagawa D, Nakashima E, Ogiya A, Miyagi Y, Iijima K, Morizono H, Makita M, Gomi N, Oguchi M, Ito Y, Horii R, Akiyama F, Ohno S
Institution:Department of Surgical Oncology, Breast Oncology Center, Cancer Institute Hospital of the Japanese Foundation for Cancer Research, Tokyo, Japan. Electronic address: takehiko.sakai@jfcr.or.jp.; Department of Surgical Oncology, Breast Oncology Center, Cancer Institute Hospital of the Japanese Foundation for Cancer Research, Tokyo, Japan; Department of Breast Surgery, Nippon Medical School Musashi Kosugi Hospital, Kanagawa, Japan.; Department of Diagnostic Radiology, Breast Oncology Center, Cancer Institute Hospital of the Japanese Foundation for Cancer Research, Tokyo, Japan.; Department of Radiation Oncology, Breast Oncology Center, Cancer Institute Hospital of the Japanese Foundation for Cancer Research, Tokyo, Japan.; Department of Medical Oncology, Breast Oncology Center, Cancer Institute Hospital of the Japanese Foundation for Cancer Research, Tokyo, Japan.
Journal:Am J Surg. 2017 Jul;214(1):111-116. doi: 10.1016/j.amjsurg.2016.10.024. Epub 2016 Nov 30.

13:Ductal carcinoma in situ and ductal carcinoma in situ with microinvasion: correlation of FDG uptake with histological and biological prognostic factors.
Authors:Seo YY, Yoo IR, Park SY, Oh JK, Kim SH, Sohn HS
Institution:Department of Nuclear Medicine, Inje University Sanggye Paik Hospital, 1342 Dongil-ro, Nowon-gu, Seoul, 01757, Republic of Korea.; Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul, 06591, Republic of Korea. iryoo@catholic.ac.kr.
Journal:Breast Cancer. 2017 May;24(3):353-361. doi: 10.1007/s12282-016-0710-7. Epub 2016 Jun 16.

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