October 2020 Issue

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Lymphedema abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Lymphedema. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Lymphedema. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Lymphedema every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content, Inc.

1:Body Mass Index and Lymphedema Morbidity: Comparison of Obese versus Normal-Weight Patients.
Authors:Greene AK, Zurakowski D, Goss JA
Institution:Boston, Mass. From the Department of Plastic and Oral Surgery and the Lymphedema Program, and the Departments of Anesthesiology and Surgery, Boston Children's Hospital, Harvard Medical School.
Journal:Plast Reconstr Surg. 2020 Aug;146(2):402-407. doi: 10.1097/PRS.0000000000007021.

2:Interventions for Breast Cancer-Related Lymphedema: Clinical Practice Guideline From the Academy of Oncologic Physical Therapy of APTA.
Authors:Davies C, Levenhagen K, Ryans K, Perdomo M, Gilchrist L
Institution:C. Davies, PT, PhD, Nursing and Allied Health Research Office, Baptist Health Lexington, 1740 Nicholasville Rd, Lexington, KY 40503 (USA.).
Journal:Phys Ther. 2020 Jul 19;100(7):1163-1179. doi: 10.1093/ptj/pzaa087.

3:Patients who report cording after breast cancer surgery are at higher risk of lymphedema: Results from a large prospective screening cohort.
Authors:Brunelle CL, Roberts SA, Shui AM, Gillespie TC, Daniell KM, Naoum GE, Taghian A
Institution:Department of Physical and Occupational Therapy, Massachusetts General Hospital, Boston, Massachusetts. Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts.
Journal:J Surg Oncol. 2020 Aug;122(2):155-163. doi: 10.1002/jso.25944. Epub 2020 Jun 4.

4:Volumetric Differences in the Suprafascial and Subfascial Compartments of Patients with Secondary Unilateral Lower Limb Lymphedema.
Authors:Chu SY, Wang SC, Chan WH, Wang N, Huang YL, Cheng MH, Cederna PS
Institution:Taoyuan, Taiwan; and Ann Arbor, Mich. From the Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital; Institute for Radiological Research, Chang Gung University; the Section of P
Journal:Plast Reconstr Surg. 2020 Jun;145(6):1528-1537. doi: 10.1097/PRS.0000000000006844.

5:Precision and reliability of tape measurements in the assessment of head and neck lymphedema.
Authors:Chotipanich A, Kongpit N
Institution:Department of Medical Services, Head and Neck Unit, Chonburi Cancer Hospital, Ministry of Public Health, Chonburi, Thailand. Department of Medical Services, Nursing Unit, Chonburi Cancer Hospital, Ministry of Public Health, Chonburi, Thailand.
Journal:PLoS One. 2020 May 18;15(5):e0233395. doi: 10.1371/journal.pone.0233395. eCollection 2020.

6:Resistance exercise and breast cancer-related lymphedema-a systematic review update and meta-analysis.
Authors:Hasenoehrl T, Palma S, Ramazanova D, K├Âlbl H, Dorner TE, Keilani M, Crevenna R
Institution:Department of Physical Medicine, Rehabilitation and Occupational Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Journal:Support Care Cancer. 2020 Aug;28(8):3593-3603. doi: 10.1007/s00520-020-05521-x. Epub 2020 May 15.

7:Effects of Health Belief Model based nursing interventions offered at home visits on lymphedema prevention in women with breast cancer: A randomised controlled trial.
Authors:Cal A, Bahar Z, Gorken I
Institution:Department of Nursing, Ankara Medipol University School of Health Sciences, Ankara, Turkey. Department of Radiation Oncology, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey.
Journal:J Clin Nurs. 2020 Jul;29(13-14):2521-2534. doi: 10.1111/jocn.15271. Epub 2020 Apr 17.

8:Optimizing Quality of Life for Patients with Breast Cancer-Related Lymphedema: A Prospective Study Combining DIEP Flap Breast Reconstruction and Lymphedema Surgery.
Authors:Chang EI, Ibrahim A, Liu J, Robe C, Suami H, Hanasono MM, Nguyen AT
Institution:Houston, Texas From the Department of Plastic Surgery, University of Texas M. D. Anderson Cancer Center.
Journal:Plast Reconstr Surg. 2020 Apr;145(4):676e-685e. doi: 10.1097/PRS.0000000000006634.

9:MRL as one-shot examination for patients suffering from lymphedema.
Authors:Gentili F, Guerrini S, Mazzei FG, Volterrani L, Mazzei MA
Institution:Department of Medicine and Surgery, Section of Radiology, Azienda Ospedaliera Universitaria di Parma, Viale Antonio Gramsci 14, 43126, Parma, Italy. Department of Medical, Surgical and Neuro Sciences, Diagnostic Imaging, University of Siena, Azienda Ospedaliera Universitaria Senese, Viale Bracci 10, 53100, Siena, Italy.
Journal:Radiol Med. 2020 Aug;125(8):798-799. doi: 10.1007/s11547-020-01162-6. Epub 2020 Mar 17.

10:Effect of lymphedema self-management group-based education compared with social network-based education on quality of life and fear of cancer recurrence in women with breast cancer: a randomized controlled clinical trial.
Authors:Omidi Z, Kheirkhah M, Abolghasemi J, Haghighat S
Institution:Department of Reproductive Health and Midwifery, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran. Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran.
Journal:Qual Life Res. 2020 Jul;29(7):1789-1800. doi: 10.1007/s11136-020-02455-z. Epub 2020 Mar 9.

11:Clinical and Scintigraphic Predictors of Primary Lower Limb Lymphedema-Volume Reduction During Complete Decongestive Physical Therapy.
Authors:Vignes S, Simon L, Benoughidane B, Simon M, Fourgeaud C
Institution:Department of Lymphology, Hopital Cognacq-Jay, 15, rue Eugene-Millon, 75015 Paris, France. Department of Lymphology, Hopital Cognacq-Jay.
Journal:Phys Ther. 2020 May 18;100(5):766-772. doi: 10.1093/ptj/pzaa012.

12:Risk factors for lower limb lymphedema in gynecologic cancer patients after initial treatment.
Authors:Kunitake T, Kakuma T, Ushijima K
Institution:Clinical Research Center, Kurume University Hospital, 67 Asahi-machi, Kurume-shi, Fukuoka, 830-0011, Japan. Department of Obstetrics and Gynecology, Kurume University School of Medicine, Kurume, Fukuoka, Japan.
Journal:Int J Clin Oncol. 2020 May;25(5):963-971. doi: 10.1007/s10147-019-01608-6. Epub 2020 Jan 6.

13:Volumetric analysis of Non-contrast Magnetic Resonance Lymphangiography in patients affected by lower extremities primary lymphedema.
Authors:Cellina M, Gibelli D, Floridi C, Oliva G
Institution:Reparto di Radiologia, Ospedale Fatebenefratelli, ASST Fatebenefratelli Sacco, Milano, Piazza Principessa Clotilde 3, 20121, Milan, Italy.
Journal:Radiol Med. 2020 Apr;125(4):432-435. doi: 10.1007/s11547-019-01122-9. Epub 2019 Dec 17.

14:Screening for breast cancer-related lymphoedema: self-assessment of symptoms and signs.
Authors:Svensson BJ, Dylke ES, Ward LC, Black DA, Kilbreath SL
Institution:Faculty of Health Sciences, The University of Sydney, PO Box 170, Lidcombe, NSW, 1825, Australia.
Journal:Support Care Cancer. 2020 Jul;28(7):3073-3080. doi: 10.1007/s00520-019-05083-7. Epub 2019 Oct 22.

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