November 2019 Issue

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Lymphedema abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Lymphedema. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Lymphedema. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Lymphedema every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content, Inc.

1:The effectiveness of lymphedema self-management in the prevention of breast cancer-related lymphedema and quality of life: A randomized controlled trial.
Authors:Temur K, Kapucu S
Institution:Hacettepe University Adult Hospital, Department of General Surgery Wards, Ankara, Turkey. Turkey. Electronic address:
Journal:Eur J Oncol Nurs. 2019 Jun;40:22-35. doi: 10.1016/j.ejon.2019.02.006. Epub 2019 Feb 25.

2:Axillary reverse mapping and lymphaticovenous bypass: Lymphedema prevention through enhanced lymphatic visualization and restoration of flow.
Authors:Schwarz GS, Grobmyer SR, Djohan RS, Cakmakoglu C, Bernard SL, Radford D, Al-Hilli Z, Knackstedt R, Djohan M, Valente SA
Institution:Department of Plastic Surgery, Cleveland Clinic, Cleveland, Ohio. Cleveland, Ohio.
Journal:J Surg Oncol. 2019 Aug;120(2):160-167. doi: 10.1002/jso.25513. Epub 2019 May 29.

3:Fibrosis and secondary lymphedema: chicken or egg?
Authors:Kataru RP, Wiser I, Baik JE, Park HJ, Rehal S, Shin JY, Mehrara BJ
Institution:Department of Surgery, Plastic and Reconstructive Surgery Service, Memorial Sloan Kettering Cancer Center, New York, New York. Electronic address:
Journal:Transl Res. 2019 Jul;209:68-76. doi: 10.1016/j.trsl.2019.04.001. Epub 2019 Apr 4.

4:The social, physical and economic impact of lymphedema and hydrocele: a matched cross-sectional study in rural Nigeria.
Authors:Eneanya OA, Garske T, Donnelly CA
Institution:MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College London, Faculty of Medicine, Norfolk Place, London, W2 1PG, UK.; Department of Statistics, University of Oxford, Oxford, UK.
Journal:BMC Infect Dis. 2019 Apr 23;19(1):332. doi: 10.1186/s12879-019-3959-6.

5:A pilot study of lower extremity lymphedema, lower extremity function, and quality of life in women after minimally invasive endometrial cancer staging surgery.
Authors:Watson CH, Lopez-Acevedo M, Broadwater G, Kim AH, Ehrisman J, Davidson BA, Lee PS, Valea F, Berchuck A, Havrilesky LJ
Institution:Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Duke University, Durham, NC, United States of America. Electronic address:; Department of Obstetrics and Gynecology, George Washington University Hospital, Washington, DC, United States of America.; Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC, United States of America.; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Duke University, Durham, NC, United States of America; Duke Cancer Institute, Durham, NC, United States of America.; Department of Obstetrics and Gynecology Virginia Tech Carilion School of Medicine Roanoke, VA, United States of America.
Journal:Gynecol Oncol. 2019 May;153(2):399-404. doi: 10.1016/j.ygyno.2019.02.021. Epub 2019 Mar 15.

6:Effectiveness of a precast adjustable compression system compared to multilayered compression bandages in the treatment of breast cancer-related lymphoedema: a randomized, single-blind clinical trial.
Authors:Pujol-Blaya V, Salinas-Huertas S, Catasus ML, Pascual T, Belmonte R
Institution:1 Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Journal:Clin Rehabil. 2019 Apr;33(4):631-641. doi: 10.1177/0269215518821785. Epub 2019 Jan 4.

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