Sjogren's Syndrome
December 2019 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Sjogren's Syndrome abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Sjogren's Syndrome. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Sjogren's Syndrome. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Sjogren's Syndrome every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:B cell depletion with rituximab in the treatment of primary Sjogren's syndrome: what have we learnt?
Authors:Grigoriadou S, Chowdhury F, Pontarini E, Tappuni A, Bowman SJ, Bombardieri M
Institution:Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Queen Mary University of London, UK. m.bombardieri@qmul.ac.uk.; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, and Department of Oral Medicine, Institute of Dentistry, Bart's and The London School of Medicine and Dentistry, Queen Mary University of London, UK.; Rheumatology Research Group, Institute of Inflammation and Ageing, University of Birmingham, and Rheumatology Department, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Journal:Clin Exp Rheumatol. 2019 May-Jun;37 Suppl 118(3):217-224. Epub 2019 Aug 28.

2:The kaleidoscope of neurological manifestations in primary Sjogren's syndrome.
Authors:Alunno A, Carubbi F, Bartoloni E, Cipriani P, Giacomelli R, Gerli R
Institution:Rheumatology Unit, Department of Medicine, University of Perugia, Italy. University of L'Aquila, and Department of Medicine, ASL 1 Avezzano-Sulmona-L'Aquila, Italy. University of L'Aquila, Italy. University of L'Aquila, Italy. roberto.gerli@unipg.it.
Journal:Clin Exp Rheumatol. 2019 May-Jun;37 Suppl 118(3):192-198. Epub 2019 Aug 28.

3:One year in review 2019: Sjogren's syndrome.
Authors:Cafaro G, Croia C, Argyropoulou OD, Leone MC, Orlandi M, Finamore F, Cecchettini A, Ferro F, Baldini C, Bartoloni E
Institution:Rheumatology Unit, Department of Medicine, University of Perugia, Italy. University of Pisa, Italy. University of Athens, Greece. of Florence, Italy. of Pisa, Italy. of Pisa, Italy. chiara.baldini74@gmail.com.
Journal:Clin Exp Rheumatol. 2019 May-Jun;37 Suppl 118(3):3-15. Epub 2019 Jul 16.

4:Sjogren's syndrome is not a risk factor for periodontal disease: a systematic review.
Authors:Maarse F, Jager DHJ, Alterch S, Korfage A, Forouzanfar T, Vissink A, Brand HS
Institution:Department of Maxillofacial Surgery and Oral Pathology, Amsterdam UMC and Academic Centre for Dentistry Amsterdam (ACTA), Vrije Universiteit Amsterdam, The Netherlands. f.maarse@vumc.nl.; Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam (ACTA), Amsterdam, The Netherlands.; Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, The Netherlands.
Journal:Clin Exp Rheumatol. 2019 May-Jun;37 Suppl 118(3):225-233. Epub 2019 Aug 28.

5:Present and novel biologic drugs in primary Sjogren's syndrome.
Authors:Fasano S, Isenberg DA
Institution:Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Campania L. Vanvitelli, Naples, Italy. serena.fasano@unicampania.it.
Journal:Clin Exp Rheumatol. 2019 May-Jun;37 Suppl 118(3):167-174. Epub 2019 Apr 26.

6:The pipeline of targeted therapies under clinical development for primary Sjogren's syndrome: A systematic review of trials.
Authors:Felten R, Scher F, Sibilia J, Gottenberg JE, Arnaud L
Institution:Service de rhumatologie, Hopitaux Universitaires de Strasbourg, F-67000 Strasbourg, France.; Laboratoire d'Immunologie, Immunopathologie et Chimie Therapeutique, Institut de Biologie Moleculaire et Cellulaire (IBMC), CNRS UPR3572, France; RESO : Centre de Reference des Maladies Autoimmunes Systemiques Rares Est Sud-Ouest, France.; Service de Pharmacie-Sterilisation, Hopitaux Universitaires de Strasbourg, France.; Service de rhumatologie, Hopitaux Universitaires de Strasbourg, F-67000 Strasbourg, France.; RESO : Centre de Reference des Maladies Autoimmunes Systemiques Rares Est Sud-Ouest, France; INSERM UMR_S1109, Universite de Strasbourg, F-67000 Strasbourg, France. Electronic address: Laurent.arnaud@chru-strasbourg.fr.
Journal:Autoimmun Rev. 2019 Jun;18(6):576-582. doi: 10.1016/j.autrev.2018.12.008. Epub 2019 Apr 6.

7:Dental implants in patients with Sjogren's syndrome: a case series and a systematic review.
Authors:Chrcanovic BR, Kisch J, Wennerberg A
Institution:Department of Prosthodontics, Faculty of Odontology, Malmo University, Malmo, Sweden. Electronic address: bruno.chrcanovic@mau.se. Sweden. Electronic address: jeno.kisch@mau.se. Goteborg, Sweden. Electronic address: ann.wennerberg@odontologi.gu.se.
Journal:Int J Oral Maxillofac Surg. 2019 Sep;48(9):1250-1259. doi: 10.1016/j.ijom.2019.02.005. Epub 2019 Mar 1.

8:Sjogren's Syndrome: More Than Just Dry Eye.
Authors:Akpek EK, Bunya VY, Saldanha IJ
Institution:The Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, MD. Synthesis in Health, Brown University School of Public Health, Providence, RI.
Journal:Cornea. 2019 May;38(5):658-661. doi: 10.1097/ICO.0000000000001865.

9:Ten-year observation of patients with primary Sjogren's syndrome: Initial presenting characteristics and the associated outcomes.
Authors:Tsukamoto M, Suzuki K, Takeuchi T
Institution:Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan. of Medicine, Tokyo, Japan. of Medicine, Tokyo, Japan.
Journal:Int J Rheum Dis. 2019 May;22(5):929-933. doi: 10.1111/1756-185X.13464. Epub 2018 Dec 26.

10:Phenotypic features and predictors of the clinical severity of keratoconjunctivitis sicca and salivary gland dysfunction in patients with Sjogren's syndrome: a longitudinal analysis of the Korean Initiative of primary Sjogren's Syndrome (KISS) cohort.
Authors:Koh JH, Lee J, Chung SH, Kwok SK, Park SH
Institution:a Division of Rheumatology, Department of Internal Medicine, Pusan National University Hospital , Pusan National University School of Medicine , Busan , Republic of Korea.; b Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine , The Catholic University of Korea , Seoul , Republic of Korea.; c Department of Ophthalmology, Seoul St. Mary's Hospital, College of Medicine , The Catholic University of Korea , Seoul , Republic of Korea.
Journal:Scand J Rheumatol. 2019 May;48(3):198-206. doi: 10.1080/03009742.2018.1504982. Epub 2018 Nov 26.

11:Pulmonary manifestations of Sjogren's syndrome.
Authors:Hatron PY, Tillie-Leblond I, Launay D, Hachulla E, Fauchais AL, Wallaert B
Institution:Service de medecine interne, Centre national de reference des maladies systemiques et auto-immunes rares (sclerodermie), universite Lille2, CHRU de Lille, place de Verdun, 59037 Lille, France. pyhatron@chru-lille.fr
Journal:Presse Med. 2011 Jan;40(1 Pt 2):e49-64. Epub 2010 Dec 30.

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