November 2019 Issue

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Spondylolisthesis abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Spondylolisthesis. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Spondylolisthesis. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Spondylolisthesis every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.

1:Sex Differences in Opioid Use in Patients With Symptomatic Lumbar Stenosis or Spondylolisthesis Undergoing Lumbar Decompression and Fusion.
Authors:Adogwa O, Davison MA, Vuong V, Desai SA, Lilly DT, Moreno J, Cheng J, Bagley C
Institution:Department of Neurosurgery, Rush University Medical Center, Chicago, Illinois. Dallas, Texas. Ohio. Dallas, Texas.
Journal:Spine (Phila Pa 1976). 2019 Jul 1;44(13):E800-E807. doi: 10.1097/BRS.0000000000002965.

2:Lumbar spondylolisthesis: modern registries and the development of artificial intelligence.
Authors:Ghogawala Z, Dunbar MR, Essa I
Institution:1Alan L. and Jacqueline B. Stuart Spine Research Center, Department of Neurosurgery, Lahey Hospital & Medical Center, Burlington, Massachusetts. Massachusetts; and. Neurosurgery, Lahey Hospital & Medical Center, Burlington, Massachusetts.
Journal:J Neurosurg Spine. 2019 Jun 1;30(6):729-735. doi: 10.3171/2019.2.SPINE18751.

3:Artificial Intelligence for the Treatment of Lumbar Spondylolisthesis.
Authors:Ghogawala Z, Dunbar M, Essa I
Institution:Department of Neurosurgery, Lahey Hospital and Medical Center, 41 Mall Road, Burlington, MA 01805, USA; Department of Neurosurgery, Tufts University School of Medicine, Boston, MA, USA. Electronic address: zoher.ghogawala@lahey.org. Burlington, MA 01805, USA. Northwest, Atlanta, GA 30332-0320, USA.
Journal:Neurosurg Clin N Am. 2019 Jul;30(3):383-389. doi: 10.1016/j.nec.2019.02.012.

4:Summary of Guidelines for the Treatment of Lumbar Spondylolisthesis.
Authors:Chan AK, Sharma V, Robinson LC, Mummaneni PV
Institution:Department of Neurological Surgery, University of California, San Francisco, 505 Parnassus Avenue M779, San Francisco, CA 94143, USA. Electronic address: andrew.chan@ucsf.edu.
Journal:Neurosurg Clin N Am. 2019 Jul;30(3):353-364. doi: 10.1016/j.nec.2019.02.009.

5:Surgical Treatment of Lumbar Spondylolisthesis in the Elderly.
Authors:Chakravarthy V, Patel A, Kemp W, Steinmetz M
Institution:Department of Neurosurgery, Cleveland Clinic Learner College of Medicine of Case Western Reserve University, 9500 Euclid Avenue, Cleveland, OH 44106, USA. Electronic address: steinmm@ccf.org.; University of Arizona School of Medicine, 1501 N Campbell Avenue, Tucson, AZ 85724, USA.
Journal:Neurosurg Clin N Am. 2019 Jul;30(3):341-352. doi: 10.1016/j.nec.2019.02.008. Epub 2019 Apr 19.

6:Surgical Versus Nonsurgical Treatment of Lumbar Spondylolisthesis.
Authors:Karsy M, Bisson EF
Institution:Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, 175 N Medical Drive East, Salt Lake City, UT 84132, USA. Electronic address: neuropub@hsc.utah.edu.
Journal:Neurosurg Clin N Am. 2019 Jul;30(3):333-340. doi: 10.1016/j.nec.2019.02.007. Epub 2019 Apr 19.

7:Rethinking Surgical Treatment of Lumbar Spondylolisthesis: Anatomic Considerations.
Authors:Minamide A, Yoshida M, Yamada H, Simpson AK
Institution:Department of Orthopaedic Surgery, Division of Minimally Invasive Spine Surgery, Wakayama Medical University, 811-1 Kimiidera, Wakayama City, Wakayama 641-8510, Japan. Electronic address: minamide@wakayama-med.ac.jp. Wakayama City, Wakayama 641-8510, Japan. Wakayama City, Wakayama 641-8510, Japan. Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
Journal:Neurosurg Clin N Am. 2019 Jul;30(3):323-331. doi: 10.1016/j.nec.2019.02.006. Epub 2019 Apr 19.

8:Lateral Approaches for the Surgical Treatment of Lumbar Spondylolisthesis.
Authors:McGowan JE, Kanter AS
Institution:Department of Neurosurgery, University of Pittsburgh Medical Center, 200 Lothrop Street, Suite B400, Pittsburgh, PA 15213, USA. Electronic address: mcgowanje@upmc.edu.
Journal:Neurosurg Clin N Am. 2019 Jul;30(3):313-322. doi: 10.1016/j.nec.2019.02.005.

9:Minimally Invasive Approaches for Surgical Treatment of Lumbar Spondylolisthesis.
Authors:Hussain I, Kirnaz S, Wibawa G, Wipplinger C, Hartl R
Institution:Department of Neurological Surgery, Weill Cornell Medical College, New York Presbyterian Hospital, 525 East 68th Street, Box 99, New York, NY 10065, USA. Electronic address: sek2024@med.cornell.edu.
Journal:Neurosurg Clin N Am. 2019 Jul;30(3):305-312. doi: 10.1016/j.nec.2019.02.004. Epub 2019 Apr 19.

10:Degenerative Lumbar Spondylolisthesis: Definition, Natural History, Conservative Management, and Surgical Treatment.
Authors:Bydon M, Alvi MA, Goyal A
Institution:Department of Neurosurgery, Mayo Clinic Neuro-Informatics Lab, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA. Electronic address: Bydon.mohamad@mayo.edu.
Journal:Neurosurg Clin N Am. 2019 Jul;30(3):299-304. doi: 10.1016/j.nec.2019.02.003.

11:High-Grade Lumbar Spondylolisthesis.
Authors:Beck AW, Simpson AK
Institution:Department of Orthopaedic Surgery, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA. Electronic address: asimpson@bwh.harvard.edu.
Journal:Neurosurg Clin N Am. 2019 Jul;30(3):291-298. doi: 10.1016/j.nec.2019.02.002.

12:Isthmic Lumbar Spondylolisthesis.
Authors:Bhalla A, Bono CM
Institution:Spine Trauma, Department of Orthopaedic Surgery, Harbor-UCLA Medical Center, Torrance, CA, USA. Medical School, Orthopaedic Spine Center, 55 Fruit Street, Yawkey Building, Suite 3A, Boston, MA 02114, USA. Electronic address: cmbono@mgh.harvard.edu.
Journal:Neurosurg Clin N Am. 2019 Jul;30(3):283-290. doi: 10.1016/j.nec.2019.02.001. Epub 2019 Apr 19.

13:Accuracy of Robot-Assisted Percutaneous Pedicle Screw Placement for Treatment of Lumbar Spondylolisthesis: A Comparative Cohort Study.
Authors:Yang JS, He B, Tian F, Liu TJ, Liu P, Zhang JN, Liu SC, Tuo Y, Chu L, Hao DJ
Institution:Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China (mainland).; Department of Orthopedics, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China (mainland).
Journal:Med Sci Monit. 2019 Apr 4;25:2479-2487. doi: 10.12659/MSM.913124.

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