July 2019 Issue

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Spondylolisthesis abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Spondylolisthesis. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Spondylolisthesis. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Spondylolisthesis every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.

1:Selective versus multi-segmental decompression and fusion for multi-segment lumbar spinal stenosis with single-segment degenerative spondylolisthesis.
Authors:Sun W, Xue C, Tang XY, Feng H, Yuan F, Guo KJ, Zhao J
Institution:Department of Orthopaedic Surgery, The Affiliated Hospital of Xuzhou Medical University, 99 Huaihai Xi Road, Xuzhou, Jiangsu Province, People's Republic of China.; Department of Orthopaedic Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, 639 Zhizaoju Road, Shanghai, People's Republic of China. 13952260339@139.com.
Journal:J Orthop Surg Res. 2019 Feb 12;14(1):46. doi: 10.1186/s13018-019-1092-2.

2:rhBMP in lumber fusion for lumbar spondylolisthesis: A systematic review and meta-analysis.
Authors:Han PF, Chen TY, Zhang ZL, Li XD, Li PC, Wei L, Lu Z, Wei XC
Institution:Department of Orthopaedic, The Second People's Hospital of Changzhi, Changzhi, Shanxi Province, China; Department of Orthopaedic, The Second Clinical Medical College of Shanxi Medical University, Shanxi Key Laboratory of Bone and Soft Tissue Injury Repair, Taiyuan, Shanxi Province, China.; Department of Orthopaedic, The Second Clinical Medical College of Shanxi Medical University, Shanxi Key Laboratory of Bone and Soft Tissue Injury Repair, Taiyuan, Shanxi Province, China. Electronic address: sdeygksys@163.com.; Department of Orthopaedic, The Second People's Hospital of Changzhi, Changzhi, Shanxi Province, China.
Journal:Chin J Traumatol. 2019 Feb;22(1):51-58. doi: 10.1016/j.cjtee.2018.10.003. Epub 2019 Jan 7.

3:Transpedicular lag screw placement in traumatic cervical spondylolisthesis: Case report and systematic review of the literature.
Authors:Bakhsheshian J, Sizdahkhani S, Ohiorhenuan I, Buchanan IA, Strickland B, Pham MH
Institution:Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States. Electronic address: martinpham@gmail.com.
Journal:J Clin Neurosci. 2019 May;63:256-262. doi: 10.1016/j.jocn.2019.01.036. Epub 2019 Feb 5.

4:Follow-up score, change score or percentage change score for determining clinical important outcome following surgery? An observational study from the Norwegian registry for Spine surgery evaluating patient reported outcome measures in lumbar spinal stenosis and lumbar degenerative spondylolisthesis.
Authors:Austevoll IM, Gjestad R, Grotle M, Solberg T, Brox JI, Hermansen E, Rekeland F, Indrekvam K, Storheim K, Hellum C
Institution:Kysthospitalet in Hagevik, Orthopedic Clinic, Haukeland, University Hospital, Hagaviksbakken 25, 5217 Hagevik, Bergen, Norway. imau@helse-bergen.no.; Department of Clinical Medicine, University of Bergen, Christies gate 6, 5007 Bergen, Bergen, Norway. imau@helse-bergen.no.; The Norwegian Registry for Spine Surgery (NORspine), Northern Norway Regional Health Authority, Postboks 20, 9038 Tromso, Bodo, Norway. imau@helse-bergen.no.; Research Department, Division of Psychiatry, Haukeland University Hospital, Sanviksleitet 1, 5036 Bergen, Bergen, Norway.; Research and Communication Unit for Musculoskeletal Health (FORMI), Oslo University Hospital, PB 4950 Nydalen, 0424, Oslo, Oslo, Norway.
Journal:BMC Musculoskelet Disord. 2019 Jan 18;20(1):31. doi: 10.1186/s12891-018-2386-y.

5:The Effects of Microdecompression on Patients with Lumbar Degenerative Spinal Stenosis with or without Degenerative Spondylolisthesis.
Authors:Ogden M, Yuksel U, Bakar B, Akkaya S, Kamasak K, Dagli AT
Institution:Kirikkale University, Faculty of Medicine, Department of Neurosurgery, Kirikkale, Turkey.
Journal:Turk Neurosurg. 2019;29(2):205-212. doi: 10.5137/1019-5149.JTN.22988-18.2.

6:Does Concomitant Degenerative Spondylolisthesis Influence the Outcome of Decompression Alone in Degenerative Lumbar Spinal Stenosis? A Meta-Analysis of Comparative Studies.
Authors:Wang M, Luo XJ, Ye YJ, Zhang Z
Institution:Department of Orthopedics, Suining Central Hospital, Suining, People's Republic of China. University, Chongqing, People's Republic of China. of China. of China. Electronic address: mrzhang1974@126.com.
Journal:World Neurosurg. 2019 Mar;123:226-238. doi: 10.1016/j.wneu.2018.11.246. Epub 2018 Dec 18.

7:Cervical Spondyloptosis Successfully Treated with Only Posterior Short Segment Fusion Using Cervical Pedicle Screw Fixation.
Authors:Kim MW, Lee SB, Park JH
Institution:Department of Neurological Surgery, Asan Medical Center, University of Ulsan College of Medicine. College of Medicine. College of Medicine.
Journal:Neurol Med Chir (Tokyo). 2019 Jan 15;59(1):33-38. doi: 10.2176/nmc.tn.2018-0213. Epub 2018 Dec 15.

8:To fuse or not to fuse: a survey among members of the German Spine Society (DWG) regarding lumbar degenerative spondylolisthesis and spinal stenosis.
Authors:Strube P, Putzier M, Siewe J, Eicker SO, Dreimann M, Zippelius T
Institution:Orthopedic Department, University Hospital Jena, Campus Waldkliniken Eisenberg, Klosterlausnitzer Str. 81, 07607, Eisenberg, Germany. patrick.strube@uni-jena.de. Charite-Universitaetsmedizin Berlin, Chariteplatz 1, 10117, Berlin, Germany. Koln (AoR), Kerpener Strasse 62, 50937, Cologne, Germany. 52, 20246, Hamburg, Germany. Hamburg Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany. Klosterlausnitzer Str. 81, 07607, Eisenberg, Germany.
Journal:Arch Orthop Trauma Surg. 2019 May;139(5):613-621. doi: 10.1007/s00402-018-3096-5. Epub 2018 Dec 12.

9:Minimally Invasive Versus Traditional Open Transforaminal Lumbar Interbody Fusion for the Treatment of Single-Level Spondylolisthesis Grades 1 and 2: A Systematic Review and Meta-Analysis.
Authors:Qin R, Liu B, Zhou P, Yao Y, Hao J, Yang K, Xu TL, Zhang F, Chen X
Institution:Medical College of Nantong University, Nantong, Jiangsu, China; Department of Orthopedics, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China.; Medical College of Nantong University, Nantong, Jiangsu, China.; Department of Orthopedics, Gaoyou Hospital of Integrated Traditional Chinese and Western Medicine, Gaoyou, Jiangsu, China.; Department of Orthopedics, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China; Jiangsu Clinical Medicine Center of Tissue Engineering and Nerve Injury Repair, Nantong, Jiangsu, China. Electronic address: xq.c@live.com.
Journal:World Neurosurg. 2019 Feb;122:180-189. doi: 10.1016/j.wneu.2018.10.202. Epub 2018 Nov 7.

10:Does minimally invasive fusion technique influence surgical outcomes in isthmic spondylolisthesis?
Authors:Ryu DS, Ahn SS, Kim KH, Park JY, Kuh SU, Chin DK, Kim KS, Cho YE
Institution:a Department of Neurosurgery, College of Medicine , Inha University , Incheon , Korea.; b Department of Neurosurgery, Spine and Spinal Cord Institute , Gangnam Severance Spine Hospital, Yonsei University College of Medicine , Seoul , Korea.
Journal:Minim Invasive Ther Allied Technol. 2019 Feb;28(1):33-40. doi: 10.1080/13645706.2018.1457542. Epub 2018 Sep 28.

11:Natural History of Cervical Degenerative Spondylolisthesis.
Authors:Park MS, Moon SH, Oh JK, Lee HW, Riew KD
Institution:Department of Orthopaedic Surgery, Hallym University Sacred Heart Hospital, Medical College of Hallym University, Gyeonggi-do, Republic of Korea. Republic of Korea. College of Hallym University, Gyeonggi-do, Republic of Korea. Hospital, Medical College of Hallym University, Seoul, Republic of Korea. NY-Presbyterian/Allen Hospital, New York.
Journal:Spine (Phila Pa 1976). 2019 Jan 1;44(1):E7-E12. doi: 10.1097/BRS.0000000000002764.

For a FREE PREVIEW of the Medifocus Guidebook on Spondylolisthesis click here

To purchase a copy of the COMPLETE Medifocus Guidebook on Spondylolisthesis click here

To subscribe to additional FREE Medifocus Digest Alert on other disease/condition areas click here

Get the Medifocus Guidebook on Spondylolisthesis...
at a Special 20% Discount

Medifocus Guidebook on Spondylolisthesis

Updated: July 5, 2019
176 Pages

This one of a kind Guidebook offers:

  • Answers to your critical health questions including the latest treatments, clinical trials, and expert research.
  • High Quality, Professional level information you can trust and understand culled from the latest peer-reviewed journals.
  • Timely, up to date content with free guidebook updates for 1 year.
  • A unique resource to find leading experts, institutions, and support organizations including contact information and hyperlinks.
  • Over 130,000 Guidebooks Sold
  • 100% Risk Free Money Back Guarantee


The Medifocus Guidebook on Spondylolisthesis is available in the following two convenient formats:


Soft-cover book that is available for immediate shipping via either U.S. Priority Mail or International AirMail (outside the U.S.).

  • Regular List Price = $36.95
  • Less 20% Discount = - $7.40
  • Discounted Price = $29.55(excluding shipping & handling)

Order the Printed Guidebook


Available for immediate download as a PDF document.

  • Regular List Price = $27.95
  • Less 20% Discount = - $5.60
  • Discounted Price = $22.35

Order the Digital Guidebook

Order by Phone

Call Toll Free in the U.S.

From Outside the U.S.

You can also receive a 20% discount when you order your Guidebook by phone.

To receive your 20% discount, simply mention the Discount Coupon Code below to the customer service representative taking your order.

Discount Coupon Code for
Phone Orders


Coupon Expires: November 21, 2019

What Our Customers Are Saying...

"The MediFocus Guidebook on Spondylolisthesis provided me with the information I needed to make an informed decision regarding my treatment. The Guidebook clearly explained the various grades of spondylolisthesis and what patients can expect at each stage. The various treatment options are also clearly explained so that you walk away with a much more realistic expectation about what to expect after treatment."
Shereveport, Louisiana

"The MediFocus Guidebook on Spondylolisthesis enabled me to have a more meaningful and serious discussion with my Orthopedic Surgeon about the various treatment options that are available to me. Your very comprehensive and informative Guidebook not only helped me prepare the right questions to ask my surgeon but also helped me better understand the answers he provided."
Plano, Texas

"Your MediFocus Guidebook on Spondylolisthesis helped me to prepare important questions to ask my doctors about the risks and complications associated with the proposed surgical solution to my low back problem. Thank you."
Malvern, Pennsylvania

Medifocus Digest Alert is published by Medifocus, Inc.
3809 Clarks Lane, Suite 100, Baltimore, MD 21215 USA
Copyright © 2019 Medifocus, Inc. All rights reserved.