Acoustic Neuroma
January 2017 Issue

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Acoustic Neuroma abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Acoustic Neuroma. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Acoustic Neuroma. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Acoustic Neuroma every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content, Inc.

1:Improved Postoperative Facial Nerve and Hearing Function in Retrosigmoid Vestibular Schwannoma Surgery Significantly Associated with Semisitting Position.
Authors:Roessler K, Krawagna M, Bischoff B, Rampp S, Ganslandt O, Iro H, Schmitt H, Buchfelder M
Institution:Department of Neurosurgery, University Hospital Erlangen, Erlangen, Germany. Electronic address:
Journal:World Neurosurg. 2016 Mar;87:290-7. doi: 10.1016/j.wneu.2015.11.089. Epub 2015 Dec 28.

2:Safety and Efficacy of Gamma Knife Radiosurgery for the Management of Koos Grade 4 Vestibular Schwannomas.
Authors:Iorio-Morin C, AlSubaie F, Mathieu D
Institution:*Neurosurgery Division, Universite de Sherbrooke, Centre Hospitalier Universitaire de Sherbrooke, Centre de Recherche du CHUS, Sherbrooke, Quebec, Canada; double daggerSaudi National Neuroscience Institute, Riyadh, Saudi Arabia.
Journal:Neurosurgery. 2016 Apr;78(4):521-30. doi: 10.1227/NEU.0000000000001154.

3:Hearing Outcomes After Stereotactic Radiosurgery for Vestibular Schwannomas : Mechanism of Hearing Loss and How to Preserve Hearing.
Authors:Han JH, Kim DG, Chung HT, Paek SH, Jung HW
Institution:Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea. Gyeonggi-do, Korea. Korea. Korea. Korea. Korea.
Journal:Adv Tech Stand Neurosurg. 2016;(43):3-36. doi: 10.1007/978-3-319-21359-0_1.

4:Retrosigmoid versus translabyrinthine approach to acoustic neuroma resection: A comparative cost-effectiveness analysis.
Authors:Semaan MT, Wick CC, Kinder KJ, Stuyt JG, Chota RL, Megerian CA
Institution:University Hospitals Ear, Nose, and Throat Institute, Department of Otolaryngology-Head and Neck Surgery, University Hospitals Case Medical Center, Cleveland, Ohio, U.S.A.; Case Western University School of Medicine, Cleveland, Ohio, U.S.A.
Journal:Laryngoscope. 2016 Feb;126 Suppl 3:S5-12. doi: 10.1002/lary.25729. Epub 2015 Oct 22.

5:Audiologic evaluation of vestibular schwannoma and other cerebellopontine angle tumors.
Authors:Kim SH, Lee SH, Choi SK, Lim YJ, Na SY, Yeo SG
Institution:a Department of Otorhinolaryngology-Head and Neck Surgery. Korea. Korea. Korea.
Journal:Acta Otolaryngol. 2016;136(2):149-53. doi: 10.3109/00016489.2015.1100326. Epub 2015 Oct 19.

6:Incidence and Risk Factors of Delayed Facial Palsy After Vestibular Schwannoma Resection.
Authors:Carlstrom LP, Copeland WR 3rd, Neff BA, Castner ML, Driscoll CL, Link MJ
Institution:*Medical Scientist Training Program, Mayo Clinic, Rochester, Minnesota; double daggerDepartment of Neurological Surgery, Mayo Clinic, Rochester, Minnesota; section signDepartment of Otorhinolaryngology, Mayo Clinic, Rochester, Minnesota.
Journal:Neurosurgery. 2016 Feb;78(2):251-5. doi: 10.1227/NEU.0000000000001015.

7:Prophylactic nimodipine treatment for cochlear and facial nerve preservation after vestibular schwannoma surgery: a randomized multicenter Phase III trial.
Authors:Scheller C, Wienke A, Tatagiba M, Gharabaghi A, Ramina KF, Ganslandt O, Bischoff B, Zenk J, Engelhorn T, Matthies C, Westermaier T, Antoniadis G, Pedro MT, Rohde V, von Eckardstein K, Kretschmer T, Kornhuber M, Steighardt J, Richter M, Barker FG 2nd, Strauss C
Institution:Departments of 1 Neurosurgery and. Germany; and. (Saale); (Saale); Massachusetts.
Journal:J Neurosurg. 2016 Mar;124(3):657-64. doi: 10.3171/2015.1.JNS142001. Epub 2015 Aug 14.

8:Long-term vestibulocochlear functional outcome following retro-sigmoid approach to resection of vestibular schwannoma.
Authors:Abboud T, Regelsberger J, Matschke J, Jowett N, Westphal M, Dalchow C
Institution:Department of Neurosurgery, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany. Martinistrasse 52, 20246, Hamburg, Germany. Hamburg, Germany. Center Hamburg-Eppendorf, Hamburg, Germany. Harvard Medical School, Boston, MA, USA. Martinistrasse 52, 20246, Hamburg, Germany. Center Hamburg-Eppendorf, Hamburg, Germany.
Journal:Eur Arch Otorhinolaryngol. 2016 Mar;273(3):719-25. doi: 10.1007/s00405-015-3561-5. Epub 2015 Feb 21.

9:Ipsilateral cochlear implantation in patients with sporadic vestibular schwannoma in the only or best hearing ear and in patients with NF2.
Authors:Lassaletta L, Aristegui M, Medina M, Aranguez G, Perez-Mora RM, Falcioni M, Gavilan J, Piazza P, Sanna M
Institution:Department of Otolaryngology, IdiPaz Research Institute, "La Paz" University Hospital, Paseo de La Castellana 261, 28046, Madrid, Spain. Esquerdo 46, 28007, Madrid, Spain. 28933, Mostoles, Madrid, Spain. Esquerdo 46, 28007, Madrid, Spain. Hospital, Paseo de La Castellana 261, 28046, Madrid, Spain. University of Chieti, Chieti. Via Emmanueli 42, 29121, Piacenza, Italy. Hospital, Paseo de La Castellana 261, 28046, Madrid, Spain. University of Chieti, Chieti. Via Emmanueli 42, 29121, Piacenza, Italy.
Journal:Eur Arch Otorhinolaryngol. 2016 Jan;273(1):27-35. doi: 10.1007/s00405-014-3450-3. Epub 2014 Dec 24.

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