Acoustic Neuroma
December 2022 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Acoustic Neuroma abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Acoustic Neuroma. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Acoustic Neuroma. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Acoustic Neuroma every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Assessing Surgical Approaches for Acoustic Neuroma Resection: Do Patients Perceive a Difference in Quality-of-Life Outcomes?
Authors:North M, Weishaar J, Nuru M, Anderson D, Leonetti JP
Institution:Department of Otolaryngology-Head and Neck Surgery, Loyola University Medical Center, Maywood IL.
Journal:Otol Neurotol. 2022 Dec 1;43(10):1245-1251. doi: 10.1097/MAO.0000000000003720.

2:Use of a Novel Clinical Decision-Making Tool in Vestibular Schwannoma Treatment.
Authors:La Monte OA, Moshtaghi O, Tang E, Du EY, Swisher AR, Dixon PR, Nemati S, Djalilian HR, Schwartz MS, Friedman RA
Institution:Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of California, San Diego, La Jolla.
Journal:Otol Neurotol. 2022 Dec 1;43(10):e1174-e1179. doi: 10.1097/MAO.0000000000003719. Epub 2022 Oct 14.

3:Stereotactic radiosurgery for Koos grade IV vestibular schwannoma in young patients: a multi-institutional study.
Authors:Dumot C, Pikis S, Mantziaris G, Xu Z, Anand RK, Nabeel AM, Sheehan D, Sheehan K, Reda WA, Tawadros SR, Abdel Karim K, El-Shehaby AMN, Emad Eldin RM, Peker S, Samanci Y, Kaisman-Elbaz T, Speckter H, Hernández W, Isidor J, Tripathi M, Madan R, Zacharia BE, Daggubati LC, Moreno NM, Álvarez RM, Langlois AM, Mathieu D, Deibert CP, Sudhakar VR, Cifarelli CP, Icaza DA, Cifarelli DT, Wei Z, Niranjan A, Barnett GH, Lunsford LD, Bowden GN, Sheehan JP
Institution:Department of Neurological Surgery, University of Virginia Health System, Charlottesville, VA, USA. jsheehan@virginia.edu.
Journal:J Neurooncol. 2022 Oct;160(1):201-208. doi: 10.1007/s11060-022-04134-0. Epub 2022 Sep 27.

4:The Natural History of Primary Inner Ear Schwannomas: Outcomes of Long-Term Follow-Up.
Authors:Khera Z, Kay-Rivest E, Friedmann DR, McMenomey SO, Thomas Roland J Jr, Jethanamest D
Institution:New York University Grossman School of Medicine.; Division of Otology and Neurotology, Department of Otolaryngology-Head and Neck Surgery, New York University Langone Health, New York, New York.
Journal:Otol Neurotol. 2022 Dec 1;43(10):e1168-e1173. doi: 10.1097/MAO.0000000000003698. Epub 2022 Sep 22.

5:Surgical management of skull base meningiomas and vestibular schwannomas.
Authors:Gambacciani C, Grimod G, Sameshima T, Santonocito OS
Institution:Department of Neurosurgery, Ospedali Riuniti Livorno, Italy.
Journal:Curr Opin Oncol. 2022 Nov 1;34(6):713-722. doi: 10.1097/CCO.0000000000000904. Epub 2022 Sep 7.

6:Cochlear Implantation for Patients with a Vestibular Schwannoma: Effect on Tinnitus Handicap.
Authors:West N, Bunne M, Sass H, Cayé-Thomasen P
Institution:Department of Otorhinolaryngology Head and Neck Surgery and Audiology, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark; Department of Clinical Medicine, University of Copenhagen Faculty of Health and Medical Sciences, Copenhagen, Denmark.
Journal:J Int Adv Otol. 2022 Sep;18(5):382-387. doi: 10.5152/iao.2022.21541.

7:Cochlear implantation: an effective modality for hearing restoration following vestibular schwannoma resection.
Authors:Doyle EJ 3rd, Samy RN
Institution:University of Cincinnati School of Medicine, 234 Albert Sabin Way, Cincinnati, Ohio, USA.
Journal:Curr Opin Otolaryngol Head Neck Surg. 2022 Oct 1;30(5):309-313. doi: 10.1097/MOO.0000000000000844.

8:Matched Comparison of Hearing Outcomes in Patients With Vestibular Schwannoma Treated With Stereotactic Radiosurgery or Observation.
Authors:Schnurman Z, Gurewitz J, Smouha E, McMenomey SO, Roland JT Jr, Golfinos JG, Kondziolka D
Institution:Department of Neurosurgery, NYU Langone Health, New York, New York, USA.
Journal:Neurosurgery. 2022 Oct 1;91(4):641-647. doi: 10.1227/neu.0000000000002089. Epub 2022 Aug 22.

9:Modern Hearing Preservation Outcomes After Vestibular Schwannoma Stereotactic Radiosurgery.
Authors:Berger A, Alzate JD, Bernstein K, Mullen R, McMenomey S, Jethanemest D, Friedmann DR, Smouha E, Sulman EP, Silverman JS, Roland JT, Golfinos JG, Kondziolka D
Institution:Department of Neurological Surgery, NYU Langone Health, Grossman School of Medicine, New York University, New York, New York, USA.
Journal:Neurosurgery. 2022 Oct 1;91(4):648-657. doi: 10.1227/neu.0000000000002090. Epub 2022 Aug 18.

10:Audiovestibular symptoms and facial nerve function comparing microsurgery versus SRS for vestibular schwannomas: a systematic review and meta-analysis.
Authors:Yakkala VK, Mammi M, Lamba N, Kandikatla R, Paliwal B, Elshibiny H, Corrales CE, Smith TR, Mekary RA
Institution:School of Pharmacy, Massachusetts College of Pharmacy and Health Sciences (MCPHS) University, Boston, MA, USA. rania.mekary@mcphs.edu.
Journal:Acta Neurochir (Wien). 2022 Dec;164(12):3221-3233. doi: 10.1007/s00701-022-05338-z. Epub 2022 Aug 13.

11:Early Translabyrinthine Surgery for Small- and Medium-Sized Vestibular Schwannomas: Consecutive Cohort Analysis of Outcomes.
Authors:Zanoletti E, Mazzoni A, Chiumenti FA, d'Avella D, Cazzador D
Institution:Otolaryngology Section, Department of Neuroscience DNS, Padova University, Padova.
Journal:Otol Neurotol. 2022 Sep 1;43(8):962-967. doi: 10.1097/MAO.0000000000003608. Epub 2022 Aug 9.

12:Hearing Preservation After Intervention in Vestibular Schwannoma.
Authors:Yancey KL, Barnett SL, Kutz W, Isaacson B, Wardak Z, Mickey B, Hunter JB
Institution:Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center.
Journal:Otol Neurotol. 2022 Sep 1;43(8):e846-e855. doi: 10.1097/MAO.0000000000003618. Epub 2022 Aug 9.

13:Safety and Efficacy of Hypofractionated Stereotactic Radiosurgery in Facial Nerve Schwannoma.
Authors:Fatima N, La Dine AK, Barnard ZR, Ko K, Peng K, Slattery WH, Lekovic GP
Institution:Department of Neurosurgery.
Journal:Otol Neurotol. 2022 Sep 1;43(8):e841-e845. doi: 10.1097/MAO.0000000000003594. Epub 2022 Jul 28.

14:Hearing Rehabilitation After Treatment of Sporadic Vestibular Schwannomas.
Authors:Kumar S, Sahana D, Nair A, Rathore L, Sahu RK, Jain A, Borde P, Tawari M, Madhariya SN, Nair S
Institution:Department of Neurosurgery, DKS Post Graduate Institute and Research Center, Raipur, Chhattisgarh, India.; Department of Neurosurgery, Sree Chitra Tirunal Institute of Medical Sciences and Technology, Trivandrum, Kerala, India.
Journal:Neurol India. 2022 May-Jun;70(3):849-856. doi: 10.4103/0028-3886.349600.

15:Progression of Hearing Loss in Observed Non-Growing Vestibular Schwannoma.
Authors:Luryi AL, Babu S, Bojrab DI, Kveton JF, Schutt CA
Institution:Department of Neurotology, Michigan Ear Institute, Farmington Hills, Michigan.
Journal:Otol Neurotol. 2022 Aug 1;43(7):e767-e772. doi: 10.1097/MAO.0000000000003563. Epub 2022 Jun 29.

16:A Systematic Review of Recent and Ongoing Clinical Trials in Patients With the Neurofibromatoses.
Authors:Acar S, Nieblas-Bedolla E, Armstrong AE, Hirbe AC
Institution:Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri; Koc University School of Medicine, Istanbul, Turkey.; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri. Electronic address: hirbea@wustl.edu.
Journal:Pediatr Neurol. 2022 Sep;134:1-6. doi: 10.1016/j.pediatrneurol.2022.06.003. Epub 2022 Jun 10.

17:Stereotactic radiosurgery ensures an effective and safe long-term control of Koos grade IV vestibular schwannomas: a single-center, retrospective, cohort study.
Authors:Umekawa M, Shinya Y, Hasegawa H, Kawashima M, Shin M, Katano A, Minamitani M, Kashio A, Kondo K, Saito N
Institution:Department of Neurosurgery, The University of Tokyo Hospital, Tokyo, 113-8655, Japan.
Journal:J Neurooncol. 2022 Aug;159(1):201-209. doi: 10.1007/s11060-022-04058-9. Epub 2022 Jun 21.

18:Acoustic neuromas associated with sudden sensorineural hearing loss.
Authors:Takahashi M, Inagaki A, Aihara N, Murakami S
Institution:Department of Otolaryngology-Head and Neck Surgery, Aichi Gakuin University School of Dentistry, Nagoya City, Japan.; Department of Otolaryngology-Head and Neck Surgery, Nagoya City University East Medical Centre, Nagoya City, Japan.
Journal:Acta Otolaryngol. 2022 May;142(5):415-418. doi: 10.1080/00016489.2022.2080862. Epub 2022 Jun 2.

19:A Critical Overview of Targeted Therapies for Vestibular Schwannoma.
Authors:Tamura R, Toda M
Institution:Department of Neurosurgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Journal:Int J Mol Sci. 2022 May 13;23(10):5462. doi: 10.3390/ijms23105462.

20:Efficacy of steroid treatment for sudden sensorineural hearing loss in patients with vestibular schwannoma.
Authors:Lee SA, Kim SY, Lee Y, Lee JD
Institution:Department of Otorhinolaryngology-Head and Neck Surgery, Soonchunhyang University Bucheon Hospital, Soonchunhyang University School of Medicine, Bucheon, Republic of Korea.
Journal:Acta Otolaryngol. 2022 May;142(5):402-405. doi: 10.1080/00016489.2022.2076905. Epub 2022 May 27.

21:Hearing Preservation in Observed Sporadic Vestibular Schwannoma: A Systematic Review.
Authors:Khandalavala KR, Saba ES, Kocharyan A, Daher GS, Lohse CM, Marinelli JP, Carlson ML
Institution:College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska.
Journal:Otol Neurotol. 2022 Jul 1;43(6):604-610. doi: 10.1097/MAO.0000000000003520.

22:Fractionated Proton Radiation Therapy and Hearing Preservation for Vestibular Schwannoma: Preliminary Analysis of a Prospective Phase 2 Clinical Trial.
Authors:Saraf A, Pike LRG, Franck KH, Horick NK, Yeap BY, Fullerton BC, Wang IS, Abazeed ME, McKenna MJ, Mehan WA, Plotkin SR, Loeffler JS, Shih HA
Institution:Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Journal:Neurosurgery. 2022 May 1;90(5):506-514. doi: 10.1227/neu.0000000000001869.

23:Long-term growth patterns of vestibular schwannomas after stereotactic radiotherapy: delayed re-growth.
Authors:Conlan O, Kontorinis G
Institution:School of Medicine, University of Glasgow, Glasgow, UK. gkontorinis@gmail.com.
Journal:Eur Arch Otorhinolaryngol. 2022 Oct;279(10):4825-4830. doi: 10.1007/s00405-022-07281-2. Epub 2022 Feb 7.

24:Hearing Preservation Microsurgery in Vestibular Schwannomas: Worth Attempting in "Larger" Tumors?
Authors:Wallerius KP, Macielak RJ, Lawlor SK, Lohse CM, Neff BA, Van Gompel JJ, Driscoll CLW, Link MJ, Carlson ML
Institution:Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota, U.S.A.
Journal:Laryngoscope. 2022 Aug;132(8):1657-1664. doi: 10.1002/lary.29968. Epub 2021 Dec 2.

25:Growing versus non-growing vestibular schwannomas: assessment of natural history.
Authors:Dardis A, Donghun K, Kontorinis G
Institution:Medical School, University of Glasgow, Glasgow, Scotland, UK.
Journal:J Laryngol Otol. 2022 Oct;136(10):934-938. doi: 10.1017/S0022215121002681. Epub 2021 Oct 1.

26:Outcomes of Salvage Resection and Radiosurgery Following Failed Primary Treatment of Vestibular Schwannomas.
Authors:Kay-Rivest E, Golfinos JG, McMenomey SO, Friedmann DR, Jethanamest D, Kondziolka D, Roland JT Jr
Institution:Department of Otolaryngology-Head and Neck Surgery, Division of Otology and Neurotology, New York University, NYU Langone Medical Center, New York, USA.
Journal:Otolaryngol Head Neck Surg. 2022 May;166(5):957-963. doi: 10.1177/01945998211039786. Epub 2021 Sep 7.

27:Long-term clinical outcomes of stereotactic radiosurgery and hypofractionated stereotactic radiotherapy using the CyberKnife(®) robotic radiosurgery system for vestibular schwannoma.
Authors:Puataweepong P, Dhanachai M, Swangsilpa T, Sitathanee C, Ruangkanchanasetr R, Hansasuta A, Pairat K
Institution:Radiation and Oncology Unit, Department of Radiology, Ramathibodi Hospital, Faculty of Medicine, Mahidol University, Bangkok, Thailand.; Radiosurgery Center, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Journal:Asia Pac J Clin Oncol. 2022 Oct;18(5):e247-e254. doi: 10.1111/ajco.13592. Epub 2021 Jul 26.

28:The impact of vestibular schwannoma and its management on employment.
Authors:Neve OM, Jansen JC, van der Mey AGL, Koot RW, de Ridder M, van Benthem PPG, Stiggelbout AM, Hensen EF
Institution:Department of Otorhinolaryngology and Head and Neck Surgery, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands. e.f.hensen@lumc.nl.
Journal:Eur Arch Otorhinolaryngol. 2022 Jun;279(6):2819-2826. doi: 10.1007/s00405-021-06977-1. Epub 2021 Jul 4.

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